Few people shop for “the best DNA health reports” in the abstract. They arrive with something specific in mind: their heart, their blood sugar, their sleep, how they will react to a particular drug. The right test is the one that goes deep on the thing you came for, and on the dozens of things you did not think to ask about. SelfDecode’s reports span 35-plus health categories, so the question shifts from “is my topic covered” to “how much further does it go.”
What the 35+ categories actually cover
Major health reports include Blood Sugar Control, Cardiovascular Health, Longevity & Healthy Aging, Brain Health, Mood & Mental Health, Sleep, Skin & Beauty, Gut Health, Histamine, Allergies, Cognition, Thyroid Health, Kidney Health, Respiratory Health, Hair Health, Mold Sensitivity, Female Fertility & Reproductive Health, Male Fertility, Perimenopause, Hormones, Mitochondrial Support, HLA DNA Autoimmunity, Cannabinoids, Hearing & Balance, Joint & Tendon Health, Eye Health, Dental & Mouth Health, Urinary Tract Health, Addictions, Fatigue, and Bone Health.
The Longevity Screener scores 130+ conditions and is the only screener we know of that combines genomics with lifestyle data (ancestry, BMI, labs, and self-reported conditions) to produce combined risk scores.
Pharmacogenomics is the most comprehensive PGx report available, covering 700+ medications, grounded in CPIC guidelines and the FDA Table of Pharmacogenomic Biomarkers (clopidogrel, warfarin, codeine, SSRIs, statins via SLCO1B1, tamoxifen, and many more).
Carrier Status covers 40+ family-planning conditions (cystic fibrosis, spinal muscular atrophy, sickle cell disease, Tay-Sachs, beta thalassemia, and more), and gene-level reports cover caffeine (CYP1A2), alcohol (ALDH2, ADH1B), lactose (LCT), folate (MTHFR), vitamin D, omega-3, and more.
Breadth without depth is just a longer list
Plenty of companies offer a long menu of “wellness traits.” The difference is what sits underneath each category. A category backed by a validated polygenic risk score and CPIC-grade pharmacogenomics is a different product from a category backed by one or two variants. SelfDecode’s breadth rests on the deeper data, which is what makes the categories worth reading.
Comparison chart
| Company | Health breadth | Pharmacogenomics | Backed by validated PRS? |
| SelfDecode | 35+ categories | 700+ medications, CPIC-grade | Yes |
| 23andMe | 95+ conditions | Limited (a few drugs) | No |
| tellmeGen | 130+ reports | Medication compatibility | No |
| LifeDNA | 130+ traits | Limited | No |
| GenoPalate | Nutrition only | No | No |
How the others stack up
23andMe. Covers 95+ health conditions and 30+ traits on a genotyping array, with only limited pharmacogenomics. Real breadth for an array product, but not backed by validated polygenic scores or a comprehensive PGx report.
tellmeGen and LifeDNA. Both market 130+ wellness reports or traits, generated largely from uploaded or array data. Useful for general wellness, but without published, validated PRS the disease-risk categories rest on weaker ground.
GenoPalate. Nutrition-focused only: optimal intake for around 23 nutrients and food recommendations. A genuinely narrow scope, useful for diet but not a broad health product.
FAQ
What health categories does a DNA test cover?
SelfDecode covers 35+ categories, including blood sugar, cardiovascular, brain, mood, sleep, thyroid, kidney, fertility, hormones, longevity, and more, plus pharmacogenomics for 700+ medications and carrier status for 40+ conditions.
Which DNA test is best for health, not just ancestry?
Look for validated polygenic risk scores and comprehensive pharmacogenomics, not just a long list of traits. SelfDecode pairs 35+ health categories with published, validated scoring and CPIC-grade PGx, which most consumer tests do not have.
Does SelfDecode cover pharmacogenomics?
Yes, the most comprehensive PGx report available, covering 700+ medications grounded in CPIC guidelines and the FDA Table of Pharmacogenomic Biomarkers, including clopidogrel, warfarin, codeine, SSRIs, and statins.
Is the Longevity Screener different from a risk report?
Yes. It scores 130+ conditions and is the only screener we know of that combines genomics with lifestyle data (ancestry, BMI, labs, and self-reported conditions) into combined risk scores, rather than genetics alone.
See the categories for yourself
Explore the full report library, or read how SelfDecode’s pharmacogenomics and pathway reports go deeper than the rest.
Part of the Why Choose SelfDecode comparison. See also: Which DNA test gives you the most reports? and The best pathway and methylation reports.
