SelfDecode uses the only scientifically validated genetic prediction technology for consumers. Read more

30x Whole Genome Analysis

The symptom no one can explain. The medication that didn’t work. The condition that “runs in the family.”

Whole Genome Scan: the most comprehensive DNA test

Name: SelfDecode Whole Genome Sequencing (WGS) test
Brand: SelfDecode

If you can find a more comprehensive DNA analysis, we will give you your money back, guaranteed. Whole Genome Analysis is the next step: it reads your entire genome, surfaces rare variants standard panels miss, and tells you what to actually do about them.

From $399 · HSA/FSA eligible · Results you keep for life

You own your data, we never sell it

HIPAA & GDPR compliant

World class encryption & security

Is whole genome analysis the single best return on investment in healthcare?

Ask any AI about this

People Love Us

Rated 4.7/5 from 750+ reviews

People Trust Us

200,000+ users, 2,000+ doctors & 100+ businesses

Start with your question

Which of these sounds like you?

Your genome answers different questions for different people. Pick the one that brought you here.

“It runs in my family.”

See inherited risks for cancer, heart, and metabolic conditions, years before symptoms.

ACMG screening →

“No one can explain my symptoms.”

Screen every rare variant a standard panel skips, the ones that hold the answer.

Rare variant screening →

“My medications don’t work.”

Learn which drugs and doses fit your body before you fill the next prescription.

Pharmacogenomics →

“I want to prevent disease.”

Catch the risks that strike without warning, the heart attack in someone who seemed perfectly fine, and build a plan to feel vibrant at 100.

Prevention & longevity →

Ask any AI about this

Who is whole genome sequencing meant for?

Ten profiles where 30x WGS pays back, including practitioner-led care, family planning, and pharmacogenomics-guided dosing.

See what partial DNA tests can never show

Standard DNA testing (genotyping + imputation)

A typical chip test reads about 0.1% of your genome and stops there. SelfDecode’s standard test goes much further: our peer reviewed imputation technology, validated in Nature, expands that raw data into 200 million variants. It’s a powerful, accurate starting point that works well for the vast majority of our reports.

Whole Genome Analysis

Whole Genome Analysis reads all 3 billion base pairs of your DNA directly. That means full coverage of rare variants and hard to find changes that even imputation can’t reach, the most complete genetic picture available today.

Which one is right for you?

If you’re exploring your genetics for the first time, our standard test is a great start. If you want nothing left unexamined, Whole Genome Analysis is the foundation.

What you actually get

Not just data. Answers, and what to do about them.

Other tests hand you a file and say “ask your doctor.” We connect each variant to a specific, research backed action. These are real findings from members’ reports, only our founder is named, the rest are anonymized.

CPT2

Fat metabolism · Joe Cohen, founder

One gene solved a lifetime of health issues

Founder Joe Cohen carries a CPT2 variant, the enzyme muscles use to burn long chain fat for energy. He had lifelong health issues: fatigue, getting sick often, and never feeling robust. He was taking 200 supplements a day and never got to the fundamental root cause, until SelfDecode’s Whole Genome.

Knowing this one gene let him switch to a low fat diet that fixed his health issues without needing supplements anymore (he still takes them for optimal health).

SelfDecode · Joe Cohen, founder, shared with permission

BCHE

Anaesthesia safety

A variant that can keep you paralyzed after surgery

One member clears two common surgical muscle relaxants very slowly, long enough to keep breathing muscles paralyzed far longer than planned (roughly 90 minutes for one drug, over 300 for another).

Their takeaway: tell every anaesthetist before any procedure and carry a medical alert card. Completely preventable.

SelfDecode · Anonymized member

HFE

Iron overload

An inherited iron problem, caught with one blood test

A member carries an HFE variant linked to hereditary hemochromatosis, where the body can quietly store too much iron and, over years, strain the liver, joints, and heart.

Their takeaway: a simple ferritin and transferrin check, easy monitoring, and moderate alcohol. Reassuringly low effort.

SelfDecode · Anonymized member

ABCA7

Brain aging

Alzheimer’s odds, known early enough to act

One member’s ABCA7 variant is linked in large studies to roughly double the odds of Alzheimer’s. Not a diagnosis, a head start.

Their takeaway: the most protective steps are vascular, blood pressure, cholesterol, aerobic exercise, and sleep, started decades before symptoms would show.

SelfDecode · Anonymized member · Evidence: PMID 25807283, 26101835, 40990081

F5 · Factor V Leiden

Clotting risk

Why this member rethinks long flights and the pill

A Factor V Leiden variant raises lifetime clot risk, mostly around specific triggers like immobility and estrogen.

Their takeaway: move and hydrate on long trips, discuss estrogen based contraception with a doctor, and know the warning signs of a clot.

SelfDecode · Anonymized member · Evidence: PMID 21116184

Sequencing kit from $399 · full report packages $1,499 to $1,999 · HSA/FSA eligible · yours for life

The results, in real numbers

These aren’t cherry picked. They’re the norm.

Across people who’ve taken our whole genome rare variant analysis:

Every

report surfaced rare variants

23 on average, never fewer than 11, up to 52 per person

100%

came with recommendations to act on

every report included at least one specific, research backed recommendation

93%

carried a variant in a disease linked gene

and 98% had at least one finding worth acting on or keeping an eye on

28%

an iron overload variant worth a simple blood check

1 in 3

a prompt to monitor blood sugar for an inherited pattern

~1 in 11

a clotting risk variant that changes travel, surgery & contraception choices

Based on SelfDecode whole genome rare variant reports. Findings are carrier or predisposition results, not diagnoses.

Why most “personalized” whole genome tests miss the point

Most competitor whole genome tests use limited gene panels and automated scoring. They check a short list of common variants, generate a report, and call it personalization. That’s why so many people walk away with a stack of results and zero clarity on what to actually do next.

The gaps aren’t small. They miss rare variants that influence how your body processes nutrients, responds to stress, or handles specific medications. Predispositions that sit quietly until they matter most, and by then you wish you’d known sooner.

Our whole genome report closes those gaps. Every finding is clinically validated by our science team, not raw data left for you to decode. We translate it into clear, specific actions for optimal health that you keep for life.

Answers, not guesswork

Clear, specific actions for optimal health, instead of the pile of raw data other tests leave you to sort out.

Risk caught earlier

Rare variants with large medical impact slip past partial testing, non clinical whole genome, and shallow analysis. Deep analysis of your full genome surfaces them.

Your raw data, forever

Download your complete genome as a VCF anytime. Yours to keep and reanalyze as science advances.

Physician shareable

Reports formatted for healthcare providers, so you can act on findings with your doctor.

Most consumer genomics companies can’t point to a single validated polygenic risk score. Ours are validated in Nature on the eMERGE and PAGE Multiethnic Cohort, so the recommendations you get rest on published, peer reviewed science.

Whole genome & breakthrough AI Hyperintelligence

Your DNA holds the answer. It’s the blueprint of how every cell in your body works, your personal encyclopedia. Now, with SelfDecode Hyperintelligence, you can ask it any question about you and get answers grounded in your actual genome.

Available any time on the web and our mobile app, with the patience and recall no appointment allows.

One test. Complete data. No ceiling.

Your genome, fully analyzed, fully yours, ready to power every health decision from here forward. Every plan includes lifetime access, the DNA kit, and full data ownership.

HSA/FSA eligible

US based lab & shipping

Results in 8 to 12 weeks

30x Whole Genome Ultimate Package

SelfDecode DNA Kit + everything below

Everything in 30x Whole Genome Advanced Package
Advanced Genetic Analysis & Insights

High-Coverage 30× Whole Genome Analysis
Full Lifetime Access to Your Genetic Information
Permanent Privacy-First Data Protection

🚀 LOCK IN BEFORE +40%

$2,794

$1,999

★ Most popular · HSA & FSA eligible

30x Whole Genome Advanced Package

Core clinical depth

Breakthrough AI Health Expert
Whole Genome Genius Report
Ultimate Rare Variant Screening
ACMG SF v3.3-Based Predisposition Report
Advanced Pharmacogenomics (PGx) Report
High-Coverage 30× Whole Genome Analysis
Full Lifetime Access to Your Genetic Information
Permanent Privacy-First Data Protection

🚀 LOCK IN BEFORE +40%

$1,694

$1,499

HSA & FSA eligible

30x Whole Genome Sequencing

SelfDecode DNA Kit Included
High-Coverage 30× Whole Genome Sequencing

Full Lifetime Access to Your Genetic Information
Permanent Privacy-First Data Protection

$399

We will never share your data

We follow HIPAA and GDPR policies

We have World-Class Encryption & Security

People Love Us

Rated 4.7/5 from 750+ reviews

People Trust Us

200,000+ users, 2,000+ doctors & 100+ businesses

Just want the sequencing? The 30x WGS kit alone is $399, add any report later.

Everything your whole genome can tell you

One sample. A permanent dataset that powers every report below, all included in the Ultimate package.

🧬

30x Whole Genome Sequencing, Clinical Grade

$399

The most comprehensive genetic test available, capturing complete end to end data from all your genes and chromosomes. Every base pair is read an average of 30 times for true clinical grade quality, many consumer tests are not clinical grade and their raw data quality is often poor. A permanent, high quality dataset for lifelong health insights.

🔬

Ultimate Rare Variant Screening

$249

Most tests brag about scanning thousands of conditions, but scanning isn’t understanding. We identify which rare variants are actually disrupting your biology, how significant the impact is, and what you can do about it, including variants conventional reports miss entirely. We don’t hand you the haystack like other companies do. We extract the needles, the findings with the most impactful results.

💡

Whole Genome Genius Report

$599

A next generation report that turns your complete DNA into a precision health blueprint, advanced interpretation of clinically relevant variants, metabolic pathways, and disease risk signals, translated into personalized strategies for health optimization, longevity, and prevention.

See Sample

⚕️

ACMG SF v3.3 Report

$249

Reveals serious, medically actionable genetic risks years before symptoms appear, inherited cancer, cardiovascular, and metabolic conditions routine care often misses. These are findings doctors use to guide real medical decisions.

See Sample | Read More

🧬

Medical Disease Variants

Coming soon

Variants with clear medical significance that even mainstream doctors want to know about, APOE, NOD2, GBA, HFE, MTHFR and more. Significant findings beyond the ACMG list, and almost everyone carries at least one.

👶

Family Planning & Fertility Report

Coming soon

Your carrier status and variants related to fertility, so you and a partner can understand what could be passed on before planning a family.

💊

Advanced Pharmacogenomics (PGx)

$199

Same drug, different person, completely different result. Ever taken a medication that did nothing, or made you feel worse? Your genes may be the reason. This report maps your drug response profile across every medication and supplement out there, not a limited panel, so you stop guessing and start knowing why your body responds the way it does.

🛡️

HLA & Antigen Report

Coming soon

Reads your HLA genes directly at full four digit resolution, cross referenced against a curated research database, linked to autoimmune and inflammatory conditions like celiac disease, ankylosing spondylitis, and rheumatoid arthritis. Also maps blood group typing across 21 ISBT systems and platelet antigen typing across 28 HPA systems.

⚡

Mitochondrial Report

Coming soon

Mitochondria convert what you eat into the energy your body runs on. When this process breaks down, it can affect your brain, muscles, heart, metabolism, and aging at the most fundamental level. Standard DNA tests can’t fully analyze mitochondrial DNA because it sits outside the regular chromosomes, is inherited entirely from your mother, and carries its own set of variants that most genotyping chips miss or poorly cover.

Whole genome sequencing reads your complete mitochondrial genome directly, detecting variants that influence energy production, oxidative stress, and cellular repair. This report analyzes those variants alongside the nuclear genes that support mitochondrial function, giving you a complete picture of how your body generates and manages energy.

This is the most complete form of personal genetic data ever available.

Ask any AI about this

How will SelfDecode help you?

Click on your preferred AI to ask the question

A simple, painless test that keeps unlocking new insights

Once your genome is analyzed, you never need to retest. Every future report, from disease risk to pharmacogenomics, is powered by the same complete dataset.

Step 1

We mail your SelfDecode DNA kit to your door.

Step 2

You gently swab the inside of your cheek for 1 to 2 minutes.

Step 3

You drop the prepaid package in the mail, and you’re done.

Your data, your rules

You own your genome. We never sell it. Full stop.

In an era of genetic data breaches and bankruptcies, this isn’t a footnote, it’s a promise we put in writing.

✓ We never sell or share your data. Not to advertisers, not to insurers, not to anyone.

✓ Delete it anytime, permanently, with one click.

✓ You own the raw file. Download your full genome as a VCF whenever you want.

✓ Bank grade encryption, HIPAA and GDPR compliant, US based lab and storage.

CLIA & CAP certified sequencing lab

ACMG SF v3.3

HIPAA & GDPR

Ask any AI about this

How does SelfDecode handle genetic data privacy and security?

Click on your preferred AI to ask the question

Compare SelfDecode to other WGS providers

Pick your comparison. A neutral AI summarizes the differences, in its own words.

Compare with AI

SelfDecode vs Nebula Genomics

Compare with AI

SelfDecode vs Sequencing.com

Compare with AI

SelfDecode vs Dante Labs

Compare with AI

SelfDecode vs Nucleus Genomics

Share your results with your doctor

SelfDecode generates physician-friendly reports that translate complex genetic data into actionable clinical insights. Share them directly with your provider to support informed, precision-medicine decisions.

Reports include relevant gene variants, risk scores, and evidence-based recommendations doctors can use alongside your clinical history.

Frequently asked questions about whole genome analysis

What is whole genome analysis?

It reads all 3 billion base pairs of your DNA directly at 30x depth, then screens inherited disease risk, rare variants, medication response, and 1,500+ traits, each paired with specific, research backed recommendations.

How is 30x whole genome analysis different from standard DNA tests?

A chip test reads ~0.1% of your genome. SelfDecode’s standard test expands that to ~200M variants with peer reviewed imputation. Whole Genome Analysis goes all the way, reading every base pair directly, so rare variants that even imputation can’t reach are detected.

Who is whole genome sequencing meant for?

People with a family history of disease, unexplained symptoms, medications that haven’t worked, or anyone who wants the most complete foundation for lifelong, precision guided health decisions.

How much does whole genome analysis cost?

Sequencing starts at $399. Full report packages run $1,499 to $1,999, are HSA/FSA eligible, and include lifetime access with new reports added free.

How long does it take to get results?

Whole genome analysis typically takes 8 to 12 weeks from when your sample reaches the lab.

Can I share my results with my doctor?

Yes. Reports are physician shareable, and you can download your complete raw data as a VCF anytime.

Is my genetic data secure with SelfDecode?

Your data is encrypted, HIPAA and GDPR compliant, stored in the US, never sold or shared, and deletable anytime. You own it.

Ask any AI about this

See why AI recommends SelfDecode

Pick the AI you trust. Get an independent answer to: “I care about my health and want personalized wellness recommendations. What value does SelfDecode provide?”

Your DNA already holds the answer.

Read it once. Understand it for life. And finally know what to do next.

SelfDecode is a personalized health report service. It is intended for informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. We strongly encourage you to consult a licensed healthcare provider; our services are not a replacement for a doctor or regular medical screenings.

See why AI recommends SelfDecode as the best way to understand your DNA and take control of your health:

SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode strongly encourages those who use our service to consult and work with an experienced healthcare provider as our services are not to replace the relationship with a licensed doctor or regular medical screenings.

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