SelfDecode uses the only scientifically validated genetic prediction technology for consumers. Read more

#1 Personalized DNA Testing Platform with Health Insights

Take full control of your health with the most advanced DNA analysis available. Unlike other platforms that offer only basic reports, SelfDecode combines your genetics, labs, and lifestyle data to provide you with personalized, actionable recommendations that support your health journey.

We will never share your data

We follow HIPAA and GDPR policies

We have World-Class Encryption & Security

People Love Us

Rated 4.7/5 from 750+ reviews

People Trust Us

200,000+ users, 2,000+ doctors & 80+ businesses

Compare Our Bundles

See what’s included in each bundle and pick the best value for your goals.

EssentialBundle
Essential PlusBundle
UltimateBundle
40x Whole GenomeUltimate Package
SelfDecode DNA KitGet your DNA tested with our easy-to-use, quick & painless cheek swab.
24/7 AI Health CoachYour always-available, intelligent health assistant that answers questions, tracks progress, and guides your wellness journey anytime, day or night.
Health Overview ReportA comprehensive summary of your overall health status, highlighting key areas of strength and areas that may need attention based on your data.
Diet & Nutrition ReportDiscover how your body processes nutrients, which foods work best for you, and how to optimize your diet based on your unique biology.
35+ Health TopicsDeep-dive reports covering 35+ health categories, each with personalized insights and recommendations. Topics include: Mental Health, Cognition, Gut Health, Nutrition, Food Sensitivities, Allergies, Heart & Blood Vessels, Thyroid, Sleep, Inflammation & Autoimmunity, Immunity & Infections, Energy & Fatigue, Weight & Body Fat, Blood Sugar Control, Pain, Nerve Health, Headaches & Migraines, Detox, Longevity, Joint & Tendon Health, Eye Health, Dental & Mouth Health, Bone Health, Injuries, Liver Health, Kidney Health, Sex Hormones, Sexual Health, Reproductive Health, Fitness, Skin & Beauty, Addictions, Urinary Tract Health, Respiratory Health, Hearing & Balance, and Cancer.
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Personalized Diet, Supplement, & Lifestyle RecommendationsReceive science-backed, DNA-driven suggestions tailored to your unique genetic makeup and health goals.
Lifestyle Risk AssessmentsDiscover how your daily habits, in combination with your genes, may increase or decrease your risk for specific health conditions.
Unlimited Access to Labs AnalyzerUpload lab results to get easy-to-understand interpretations, trend analysis, and personalized suggestions to optimize your health.
1500+ Comprehensive DNA Health ReportsUnlock detailed insights across hundreds of health topics, from nutrition to mental wellness, based on your DNA.
160+ Medical ReportsAccess genetic reports that reveal predispositions and potential health risks for a wide range of medical conditions.
25+ Longevity Screener Risk AssessmentsGain insight into your long-term health risks and longevity factors based on cutting-edge genetic screening: Odds ratios to evaluate your risk for 25+ medical conditions; 10-year risk scores to prioritize health conditions; Lifetime risk scores to plan for long-term health.
Detox PathwaysLearn how your genes influence your body's ability to clear toxins, with insight into key detoxification processes including Phase I, Phase II, and glutathione pathways to support personalized health strategies.
Methylation PathwayExplore key detox and cellular health processes by analyzing your DNA's impact on methylation, a critical biochemical pathway.
Histamine PathwayThe Histamine Pathway Report reveals how your genes influence histamine production, breakdown and receptor sensitivity so you can personalize diet, supplements and lifestyle.
Dopamine & Norepinephrine PathwayDiscover how your genetic variants influence dopamine and norepinephrine signaling, affecting motivation, focus, mood, and stress response.
Serotonin & Melatonin PathwayExplore how your DNA shapes serotonin and melatonin production, influencing mood regulation, sleep quality, and overall emotional wellbeing.
Male/Female Hormones PathwayUnderstand how your genes affect the production and metabolism of sex hormones including estrogen, testosterone, and progesterone, impacting reproductive health, mood, and overall vitality.
GABA & Glutamate PathwaySee how your genes shape the balance between your brain's main calming and excitatory signals, affecting anxiety, focus, and sleep.
Weight Control PathwayUnderstand the genetic factors behind appetite, fat storage, metabolism, and how your body responds to different diets and exercise.
Mitochondria PathwayExplore how your genes affect cellular energy production, stamina, and recovery at the level of your mitochondria.
Oxidative Stress PathwayFind out how well your body neutralizes free radicals, and which antioxidant strategies suit your genetics best.
Medication Check (PGx Testing) For 50+ MedicationsLearn how your genes affect your response to medications to support safer, more effective treatment plans (Pharmacogenomics).
DNAmind PGx ReportThe DNAmind PGx Report, inspired by the Genomind PGx Report, reveals how your genetics influence your body's response to medications and supplements. It helps identify how genetic variants impact drug effectiveness and side effect risks. Covers 100+ medications.
40+ Family Planning (Carrier Status) ReportsUnderstand your carrier status for inherited conditions, helping you make informed family planning decisions.
Ancestry CompositionDiscover your ancestral roots and ethnic background based on your DNA.
Deep Ancestry (Mitochondrial)Trace your maternal lineage and explore your deep ancestral origins through mitochondrial DNA analysis.
Whole Genome Analysis Exclusives
High-Coverage 40x Whole Genome AnalysisSequences all 3 billion base pairs of your DNA and reads each one about 40 times over for accuracy, compared to the ~200 million variants covered by the SelfDecode genotyping chip.
Ultimate Rare Variant ScreeningDetects rare and novel variants anywhere in your genome, including ones that no chip-based test can pick up because they aren't on the chip.
American College of Medical Genetics and Genomics (ACMG) ReportScreens the genes the ACMG recommends reporting, covering medically actionable findings for conditions where early detection can change outcomes.
Advanced Pharmacogenomics (PGx)Whole-genome-level drug response analysis, including complex gene regions and rare variants that standard PGx panels miss.
HLA & Antigen ReportYour HLA types and antigen profile, relevant to autoimmune risk, celiac disease, drug hypersensitivity, and immune system function.
Mitochondrial ReportFull sequencing of your mitochondrial genome, covering energy production and variants linked to mitochondrial conditions.
Medical Disease VariantsScreening for known pathogenic and likely pathogenic variants associated with inherited medical conditions.
Family Planning & Fertility ReportExpanded carrier screening plus fertility-related genetic insights to support family planning decisions.
$1199$899
$2,794$1,999
Identify Your Genetic Risks Across 1500+ Health Topics

Discover your unique predispositions to 1500+ health topics, including heart issues, mental health, inflammation, and more.

Get Personalized Diet, Supplement, and Lifestyle Strategies

Receive targeted diet, supplement, and lifestyle recommendations based on your DNA, labs, and goals.

Take Control of Your Health and Future Well-Being

Use your genetic insights to make proactive decisions that support long-term wellness and disease prevention.

More Than a DNA Test — A Full Health Optimization Platform

With SelfDecode, you’re not just getting genetic insights. You’re unlocking an entire platform designed to help you live better, longer:

Personalized Recommendations

Get tailored diet, supplement, and lifestyle suggestions based on your health risks and goals.

1500+ DNA Health Reports

Explore personalized insights into 1500+ health topics using advanced polygenic risk scores, and see high-level results with Health Overview and Medical Overview reports.

Lab Tracking

Optimize 4,000+ lab markers with personalized guidance.

Nutrition Planner

Receive a personalized diet suggestion, custom meal plans, recipes, and shopping lists tailored to your body.

Suggested Labs

Get a personalized list of suggested lab tests based on your DNA & health goals.

SNP & Gene Search Tool

Discover your genotype for any SNP in our database of 200M+ genetic variants.

See Everything SelfDecode Has to Offer

Discover our full suite of health reports and features in one comprehensive guide.
Our Reports & Features Summary shows all the DNA results, tools, and insights you can get with SelfDecode.

Take Charge of Your Health Today

Discover what your DNA says about your health — and what you can do about it.
SelfDecode gives you personalized insights and recommendations based on your genes, labs, and lifestyle, helping you optimize everything from sleep and mood to digestion and disease risk.

Shipping Worldwide

30-Days Money-Back Guarantee*

HSA/FSA Eligible

Essential Bundle

For anyone starting their health improvement journey. Includes 1 Health Topic, personalized recommendations, and all the essential features.

$499
$499

Essential

Bundle

SelfDecode DNA Kit Included

For those looking to dig deeper into long-term health with 1500+ reports across 35 Health topics, longevity, and medical insights.

25% OFF

Ultimate Bundle

SelfDecode DNA Kit Included

For those seeking the most comprehensive view of their health, including detox, methylation, hormones, medication response, family planning, and ancestry.

$1199
$899

28% OFF

40x Whole Genome Ultimate Package

SelfDecode DNA Kit Included

For those who want the deepest possible look at their DNA. Everything in Ultimate, plus whole genome sequencing, rare variant screening, and medical-grade reports.

$2,794
$1,999

* SelfDecode DNA kits are non-refundable. If you choose to cancel your plan within 30 days you will not be refunded the cost of the kit.

We will never share your data

We follow HIPAA and GDPR policies

We have World-Class Encryption & Security

People Love Us

Rated 4.7/5 from 750+ reviews

People Trust Us

200,000+ users, 2,000+ doctors & 80+ businesses

FAQ

What's the difference between the DNA kit bundles and the 40x Whole Genome package?

The Essential, Essential+, and Ultimate bundles use SNP genotyping. Our DNA kit reads hundreds of thousands of pre-selected genetic markers, which powers 1,500+ personalized health reports. The 40x Whole Genome Ultimate Package works differently. It sequences your entire genome at 40x coverage, reading all 3 billion base pairs. That extra depth is what unlocks the Whole Genome Analysis Exclusives: rare-variant screening, the ACMG report, advanced pharmacogenomics, HLA and antigen, mitochondrial, medical disease variants, and the family planning and fertility report.

Do I actually need whole genome sequencing?

For most people optimizing diet, supplements, and lifestyle, the Ultimate Bundle's 1,500+ reports are more than enough. Choose the 40x Whole Genome package if you want the most complete possible picture, including rare and medical-grade variants a standard DNA kit cannot detect, deeper pharmacogenomics, and carrier and fertility insights. Because it reads your whole genome, it also future-proofs your data for new reports as science advances.

Which bundle should I choose?

Essential ($499) is the starting point for core health insights. Essential+ ($799) digs deeper into long-term health. The Ultimate Bundle ($899) is our most comprehensive DNA-kit bundle, covering diet, all pathways, medication response, carrier status, and ancestry. The 40x Whole Genome Ultimate Package ($1,999) is for those who want the most powerful, complete look at their DNA, adding whole genome sequencing and medical-grade reports on top of everything in Ultimate.

How accurate are at-home DNA tests?

Very accurate for what each method reads. Our DNA kit uses clinically validated SNP genotyping, which is highly reliable for the markers it tests. The 40x Whole Genome package goes further, sequencing your whole genome at high coverage to catch rare variants a genotyping kit is not designed to detect. All reports are for informational and wellness purposes and are not a medical diagnosis.

Can I upgrade to a higher bundle after I buy?

Yes. If you start with Essential, Essential+, or Ultimate, you can upgrade anytime and instantly unlock more reports from the DNA data you have already provided, with no new sample needed. To move up to the 40x Whole Genome Ultimate Package, you will need a new test rather than a report unlock, because it sequences your entire genome.

What's included in every SelfDecode DNA bundle?

Every bundle includes a SelfDecode DNA kit, your 24/7 AI Health Coach, the Health Overview and Diet and Nutrition reports, personalized diet, supplement, and lifestyle recommendations, and unlimited access to the Labs Analyzer. Higher tiers add more reports and pathways, and the 40x Whole Genome package adds whole genome sequencing plus its exclusive medical-grade reports.

How does SelfDecode personalize my health recommendations?

SelfDecode combines your DNA, lab results, and lifestyle data to generate personalized recommendations. All suggestions are based on scientific research, and the algorithm weighs the strength of evidence and the proven impact of each recommendation when building your plan.

Can I pay with HSA or FSA?

Yes. HSA and FSA payments are accepted at checkout. You can also pay with Visa, Mastercard, Amex, Discover, PayPal, Apple Pay, Google Pay, Amazon Pay, Klarna, and Afterpay.

See why AI recommends SelfDecode as the best way to understand your DNA and take control of your health:

SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode strongly encourages those who use our service to consult and work with an experienced healthcare provider as our services are not to replace the relationship with a licensed doctor or regular medical screenings.

SelfDecode © 2026. All rights reserved.

Health reports

High Blood Sugar
Anxiety
Gluten Sensitivity
Gut Inflammation
Blood Pressure
IBS
Mood
Insomnia
PTSD
Mood Swings
Overweight
Memory Performance
Sexual Dysfunction
PCOS
Psoriasis
Joint Pain
Attention/ADHD
Chronic Fatigue / Tiredness
Allergies
Asthma
Acne
Tinnitus
Eczema
Food Allergy
Vitamin B6
Vitamin E
Restless Leg Syndrome
Grinding Teeth
Vitamin A
Magnesium
Zinc
Heart Health
Migraines
(High) Cholesterol
Headache
Chronic Pain
Back pain
Shoulder & Neck Pain
Stress
Inflammation
Omega-3 needs
Salt Sensitivity
Endurance
Power performance
Strength
Exercise recovery
Brain Fog
Female Fertility
Longevity
Addiction
Erectile Dysfunction
Male Infertility
MTHFR
Joint Inflammation
GERD
Ulcers
Sleep Apnea
Periodontitis
Varicose Veins
H. pylori
Liver Health
Canker Sores
Gallstones
Kidney Health
Gout
Hair Loss (Male-Pattern Baldness)
Riboflavin
Urticaria
Rosacea
Carpal Tunnel Syndrome
Sinus Congestion
Cavities
Artery Hardening
Vertigo
Vitiligo
Myopia
Indigestion
Excessive Sweating
Testosterone – Males
Yeast infection (Candida)
Endometriosis
Tobacco addiction
Alcohol addiction
Uterine fibroids
Length of menstrual cycle
UTI
OCD
Kidney Stones
Vitamin B12
Vitamin C
Vitamin D
Folate
Iron
Eating Disorders
Bone Health
Hypothyroidism
Hyperthyroidism
Sugar Cravings
Hearing/difficulty problem /Hearing loss
Painful Periods
Palpitations
Hemorrhoids
Hypotension
Bladder Control
Constipation
Appendicitis
Low Blood Sugar
Irregular Periods
Metabolic rate
Visceral fat
Lung Health
Anemia
Calcium
Cognition
Cognitive Decline
Seasonal Low Mood
Vitamin K
Phosphate
HRV
Cluster headaches
Knee Pain
Hip Pain
Selenium
Low back injury
Dyslexia
Cannabis addiction
Histamine Intolerance
Carnitine
Pesticide Sensitivity
Organophosphate Sensitivity
Cadmium
Lead
Melatonin
FSH
T4
T3
High PTH
Potassium
Coenzyme Q10 (CoQ10)
Chromium
Oxalate Sensitivity
Salicylate Sensitivity
Facial Wrinkles
Age Spots
Ligament Rupture (ACL Injury)
Tendon Injury (Tendinopathy)
Omega 6
Omega 6:Omega 3 Ratio
Arachidonic Acid
Oleic Acid
Alpha-Linolenic Acid
EPA
GLA
Linoleic Acid
DHA
Insulin Resistance
Sperm Motility
Homocysteine
C difficile
Pneumonia
EBV Infection
Gastrointestinal Infection
Chronic Bronchitis
Copper
Skin Elasticity
Skin Hydration
Egg allergy
ApoB
GGT
TIBC
Bioavailable Testosterone (Male)
MPV
Chloride
Free T4
Processing Speed
Short-term memory
TMAO
Air pollution sensitivity
Heart Rate
VO2 Max
Flu
Hair graying
Caffeine-Related Sleep Problems
Groin Hernia
Stretch marks
Droopy Eyelids
Strep infection
Dry eyes
Carbohydrate Consumption
Peanut allergy
Heart rate recovery
Muscle recovery
Jaw Disorders
HPV Infection
Acute Bronchitis
Chlamydia
Genital Herpes
Pancreas inflammation
Executive Function
Pyroglutamic acid
Raynaud’s
Liver Scarring
Dandruff
Bioavailable Testosterone (Female)
Shrimp allergy
Haptoglobin
Milk allergy
Beta-Alanine
Taurine
LDL Particle Size
Diarrhea
Snoring
Uric acid
Phenylalanine
Leucine
Glutamine
Valine
Glycine
Alanine
Lysine
Arginine
Histidine
Tyrosine
Cortisol
DHEAS
Insulin
Prolactin
TSH
Lactate
Ketone Bodies
IL-17A (Th17 Dominance)
Creatine Kinase
Neutrophils
Basophils
Eosinophils
Ferritin
ALT
AST
MCV
Hematocrit
RDW
SHBG
Total Protein
Albumin
MCH
Sodium
MCHC
Alkaline Phosphatase
Monocytes
Ghrelin
IL10 (Th2)
IL-6 (Th2 and Th17)
Iodine
Chili Pepper sensitivity
COMT
DRD2 (Dopamine)
Lectin Sensitivity
Thiamine
Biotin
Mold Sensitivity (Foodborne)
Chronic Lyme
BDNF
Glyphosate sensitivity
BPA Sensitivity
Pregnenolone
Luteinizing Hormone (LH)
Growth Hormone
IgA
Molybdenum
Sensitivity to Dairy (IgG Casein)
Telomere Length
Serotonin (5HIAA)
Non-Celiac Gluten Sensitivity (IgG Gliadin)
Manganese
Klotho
Mold Sensitivity (Airborne)
Amylase
Lipase
Low Sperm Count
Tryptophan
Methionine
Glutamate
Proline
Blood Calcium
Hypertriglyceridemia
HDL Cholesterol
HbA1c
Hemoglobin
Total Cholesterol
LDL Cholesterol
IGF1
Fasting Glucose
Bilirubin (total)
White blood cell count
Red blood cell count
Platelets
eGFR
Creatinine
Estradiol
Neuroticism
Sleep Quality
Lactose Intolerance
Saturated fat
Optimal diet
Unsaturated fat
Achilles tendon injury
Deep sleep
Fat
Response to Stress
Leadership
Ankle injury
Creativity
Hoarding
Protein
Optimal Exercise
Knee Injury
Rotator cuff injury
Extraversion
Risk-Taking
Happiness
Daytime Sleepiness
Morningness
Time spent watching TV
Disliking cilantro
Alcohol Sensitivity
Response to Caffeine
Snacking
Weight Regain
Sleep movement
Wearing glasses or contacts
Educational Attainment
Bitter Taste Sensitivity
Agreeableness
Aggression
Conscientiousness
Openness to experience
Physical activity
Caffeine-Related Anxiety
Naps