rs780094 (no reported alleles) was significantly associated with gout [R].

Significantly increased fasting serum insulin concentrations was seen in subjects with the ''C'' alleles [R].

The ''T'' allele was associated with higher plasma triglyceride (TG) concentrations [RR2R3R4R5].

The ''C'' allele was associated with a risk for Type 2 diabetes (T2D) and is a marker of reduced eGFR (estimated glomerular filtration rate) [RR1R2]. 

The ''C'' allele was associated with low TG levels [R].

The ''C'' allele was significantly associated with decreased levels of alanine and isoleucine and elevated levels of glutamine [R].

''T'' allele is associated with a lower diabetes risk [RR1].

''T''  allele was associated with increasing fasting triglycerides, and non-alcoholic fatty liver disease (NAFLD) in a han chinese population [RR1R2].

The ''T'' allele was associated with a 1.32-fold increase in odds of carotid plaque in American indians (P = 1.08 × 10−5) [R]. 

rs780094

Parent Gene: GCKR

Importance: 5
Less common allele: T = 30%
More common allele: C = 70%
My Genotype: Log In
Risk Allele: C, G, T, T, A, T, T, T, A, C, C, C, C, C, T, C, C, T, T, T, T, T, T, T, T, T

Disease/Trait: Fasting Blood Insulin Measurement

The C allele of rs780094 is reported to be associated with Fasting Blood Insulin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Fasting insulin-related traits (HOMA-IR).

Disease/Trait: Homa-Ir

The C allele of rs780094 is reported to be associated with Homa-ir (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Fasting insulin-related traits (HOMA-IR).

Disease/Trait: Triglyceride Measurement

The G allele of rs780094 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglycerides.

Disease/Trait: Uric Acid Measurement

The T allele of rs780094 is reported to be associated with Uric Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Uric acid levels.

Disease/Trait: Triglyceride Measurement

The T allele of rs780094 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglycerides.

Disease/Trait: C-Reactive Protein Measurement

The A allele of rs780094 is reported to be associated with C-reactive Protein Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with C-reactive protein.

Disease/Trait: Low Density Lipoprotein Cholesterol Measurement

The T allele of rs780094 is reported to be associated with Low Density Lipoprotein Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with LDL cholesterol.

Disease/Trait: Triglyceride Measurement

The T allele of rs780094 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglycerides.

Disease/Trait: Metabolite Measurement

The T allele of rs780094 is reported to be associated with Metabolite Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Metabolic traits (glucose/mannose + 54 other traits).

Disease/Trait: Metabolic Syndrome

The A allele of rs780094 is reported to be associated with Metabolic Syndrome (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Metabolic syndrome (TG).

Disease/Trait: Body Mass Index

rs780094 is associated with Body Mass Index (R) . It is reported to association with Fasting insulin-related traits (interaction with BMI). No specific risk allele was identified in the study.

Disease/Trait: Fasting Blood Insulin Measurement

rs780094 is associated with Fasting Blood Insulin Measurement (R) . It is reported to association with Fasting insulin-related traits (interaction with BMI). No specific risk allele was identified in the study.

Disease/Trait: Body Mass Index

rs780094 is associated with Body Mass Index (R) . It is reported to association with Fasting glucose-related traits (interaction with BMI). No specific risk allele was identified in the study.

Disease/Trait: Fasting Blood Glucose Measurement

rs780094 is associated with Fasting Blood Glucose Measurement (R) . It is reported to association with Fasting glucose-related traits (interaction with BMI). No specific risk allele was identified in the study.

Disease/Trait: Fasting Blood Glucose Measurement

The C allele of rs780094 is reported to be associated with Fasting Blood Glucose Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Fasting glucose-related traits (FPG).

Disease/Trait: Fasting Blood Insulin Measurement

The C allele of rs780094 is reported to be associated with Fasting Blood Insulin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Fasting insulin-related traits (FI).

Disease/Trait: Fasting Blood Insulin Measurement

The C allele of rs780094 is reported to be associated with Fasting Blood Insulin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Fasting glucose-related traits (FI).

Disease/Trait: Homa-Ir

The C allele of rs780094 is reported to be associated with Homa-ir (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Fasting glucose-related traits (HOMA-IR).

Disease/Trait: Triglyceride Measurement

The C allele of rs780094 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglycerides (Hispanic).

Disease/Trait: Urate Measurement

The T allele of rs780094 is reported to be associated with Urate Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Urate levels.

Disease/Trait: Crohn's Disease

rs780094 is associated with Crohn's Disease (R) . It is reported to association with Crohn's disease (EA). No specific risk allele was identified in the study.

Disease/Trait: Urate Measurement

The C allele of rs780094 is reported to be associated with Urate Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Urate levels in obese individuals.

Disease/Trait: Obese Body Mass Index Status

The C allele of rs780094 is reported to be associated with Obese Body Mass Index Status (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Urate levels in obese individuals.

Disease/Trait: Urate Measurement

The C allele of rs780094 is reported to be associated with Urate Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Urate levels in overweight individuals.

Disease/Trait: Overweight Body Mass Index Status

The C allele of rs780094 is reported to be associated with Overweight Body Mass Index Status (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Urate levels in overweight individuals.

Disease/Trait: Body Height

The T allele of rs780094 is reported to be associated with Body Height (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Height.

Disease/Trait: Calcium Measurement

The T allele of rs780094 is reported to be associated with Calcium Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Calcium levels.

Disease/Trait: Fasting Blood Glucose Measurement

rs780094 is associated with Fasting Blood Glucose Measurement (R) . It is reported to have a 0.052000000000000005 unit increase on Fasting plasma glucose. No specific risk allele was identified in the study.

Disease/Trait: Hypertriglyceridemia

The T allele of rs780094 is reported to be associated with Hypertriglyceridemia (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Hypertriglyceridemia.

Disease/Trait: Alcohol Consumption Measurement

The T allele of rs780094 is reported to be associated with Alcohol Consumption Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with Alcohol consumption.

Disease/Trait: Gout

The T allele of rs780094 is reported to be associated with Gout (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Renal underexcretion gout.

Disease/Trait: Hypertriglyceridemia

rs780094 is associated with Hypertriglyceridemia (R) . It is reported to increased association with Hypertriglyceridemia. No specific risk allele was identified in the study.

Disease/Trait: High Density Lipoprotein Cholesterol Measurement

rs780094 is associated with High Density Lipoprotein Cholesterol Measurement (R) . It is reported to association with Age-related disease endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Triglyceride Measurement

rs780094 is associated with Triglyceride Measurement (R) . It is reported to association with Age-related disease endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Body Mass Index

rs780094 is associated with Body Mass Index (R) . It is reported to association with Age-related disease endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Systolic Blood Pressure

rs780094 is associated with Systolic Blood Pressure (R) . It is reported to association with Age-related disease endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Diastolic Blood Pressure

rs780094 is associated with Diastolic Blood Pressure (R) . It is reported to association with Age-related disease endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Total Cholesterol Measurement

rs780094 is associated with Total Cholesterol Measurement (R) . It is reported to association with Age-related disease endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Glucose Measurement

rs780094 is associated with Glucose Measurement (R) . It is reported to association with Age-related disease endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Hematocrit

rs780094 is associated with Hematocrit (R) . It is reported to association with Age-related disease endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Ventricular Rate Measurement

rs780094 is associated with Ventricular Rate Measurement . It is reported to association with Age-related disease endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Docosapentaenoic Acid Measurement

The T allele of rs780094 is reported to be associated with Docosapentaenoic Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid).

Disease/Trait: Triglyceride Measurement

The T allele of rs780094 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglyceride levels (Asian initial, BMI unadjusted).

Disease/Trait: Gondoic Acid Measurement

The T allele of rs780094 is reported to be associated with Gondoic Acid Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with Gondoic acid (20:1n-9) levels (EA).

Disease/Trait: Gondoic Acid Measurement

The T allele of rs780094 is reported to be associated with Gondoic Acid Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with Gondoic acid (20:1n-9) levels.

Disease/Trait: High Density Lipoprotein Cholesterol Measurement

rs780094 is associated with High Density Lipoprotein Cholesterol Measurement (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Triglyceride Measurement

rs780094 is associated with Triglyceride Measurement (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Body Mass Index

rs780094 is associated with Body Mass Index (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Atrial Fibrillation

rs780094 is associated with Atrial Fibrillation (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Heart Failure

rs780094 is associated with Heart Failure (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Systolic Blood Pressure

rs780094 is associated with Systolic Blood Pressure (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Diastolic Blood Pressure

rs780094 is associated with Diastolic Blood Pressure (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Diabetes Mellitus

rs780094 is associated with Diabetes Mellitus (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Coronary Heart Disease

rs780094 is associated with Coronary Heart Disease (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Stroke

rs780094 is associated with Stroke (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Total Cholesterol Measurement

rs780094 is associated with Total Cholesterol Measurement (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Glucose Measurement

rs780094 is associated with Glucose Measurement (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Hematocrit

rs780094 is associated with Hematocrit (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Mortality

rs780094 is associated with Mortality (R) . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Cancer

rs780094 is associated with Cancer . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.

Disease/Trait: Ventricular Rate Measurement

rs780094 is associated with Ventricular Rate Measurement . It is reported to association with Age-related diseases, mortality and associated endophenotypes. No specific risk allele was identified in the study.