Each copy of the major allele ''C'' resulted in a ~8% reduction in TG (triglycerides) (p=4.6E-06) in African americans according to the Jackson heart study [R].

The ''TT'' genotype predicted a much higher TG level than other genotypes in a Han chinese population [R].

 

rs780093

Parent Gene: GCKR

Importance: 5
Less common allele: T = 29%
More common allele: C = 71%
My Genotype: Log In
Risk Allele: A, T, T, T, A, T, T, T, T, T, T, T, C, C, C, C, C, T, T, T

Disease/Trait: Triglyceride Measurement

The A allele of rs780093 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Waist Circumference - Triglycerides (WC-TG).

Disease/Trait: Metabolic Syndrome

The A allele of rs780093 is reported to be associated with Metabolic Syndrome (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Waist Circumference - Triglycerides (WC-TG).

Disease/Trait: Breast Carcinoma

The T allele of rs780093 is reported to be associated with Breast Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Breast size.

Disease/Trait: Breast Size

The T allele of rs780093 is reported to be associated with Breast Size (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Breast size.

Disease/Trait: Calcium Measurement

The T allele of rs780093 is reported to be associated with Calcium Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Calcium levels.

Disease/Trait: Urate Measurement

The T allele of rs780093 is reported to be associated with Urate Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Urate levels (Urate).

Disease/Trait: Triglyceride Measurement

The A allele of rs780093 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglycerides-Blood Pressure (TG-BP).

Disease/Trait: Blood Pressure

The A allele of rs780093 is reported to be associated with Blood Pressure (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglycerides-Blood Pressure (TG-BP).

Disease/Trait: Sex Hormone Globulin Binding Measurement

The T allele of rs780093 is reported to be associated with Sex Hormone Globulin Binding Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Sex hormone-binding globulin levels (Men + Women).

Disease/Trait: Sex Hormone Globulin Binding Measurement

The T allele of rs780093 is reported to be associated with Sex Hormone Globulin Binding Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Sex hormone-binding globulin levels (Men).

Disease/Trait: Sex Hormone Globulin Binding Measurement

The T allele of rs780093 is reported to be associated with Sex Hormone Globulin Binding Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Sex hormone-binding globulin levels (Women).

Disease/Trait: Crohn's Disease

The T allele of rs780093 is reported to be associated with Crohn's Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Crohn's disease.

Disease/Trait: Fatty Acid Measurement

The T allele of rs780093 is reported to be associated with Fatty Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Palmitic acid (16:0) levels.

Disease/Trait: Fatty Acid Measurement

The T allele of rs780093 is reported to be associated with Fatty Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Palmitoleic acid (16:1n-7) levels.

Disease/Trait: Glucose Homeostasis Measurement

rs780093 is associated with Glucose Homeostasis Measurement (R) . It is reported to have a 0.14 unit increase on Glucose homeostasis traits (SG). No specific risk allele was identified in the study.

Disease/Trait: Glucose Effectiveness Measurement

rs780093 is associated with Glucose Effectiveness Measurement (R) . It is reported to have a 0.14 unit increase on Glucose homeostasis traits (SG). No specific risk allele was identified in the study.

Disease/Trait: Triglyceride Measurement

The T allele of rs780093 is reported to be associated with Triglyceride Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Triglycerides (Hispanic).

Disease/Trait: Leptin Measurement

The C allele of rs780093 is reported to be associated with Leptin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with circulating leptin levels.

Disease/Trait: Leptin Measurement

The C allele of rs780093 is reported to be associated with Leptin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with circulating leptin levels (women).

Disease/Trait: Bmi-Adjusted Leptin Measurement

The C allele of rs780093 is reported to be associated with Bmi-adjusted Leptin Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with circulating leptin levels adjusted for BMI.

Disease/Trait: Bmi-Adjusted Leptin Measurement

The C allele of rs780093 is reported to be associated with Bmi-adjusted Leptin Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with circulating leptin levels adjusted for BMI (women).

Disease/Trait: Hypertriglyceridemia

rs780093 is associated with Hypertriglyceridemia (R) . It is reported to increased association with Hypertriglyceridemia. No specific risk allele was identified in the study.

Disease/Trait: Type Ii Diabetes Mellitus

The C allele of rs780093 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (Japanese).

Disease/Trait: Total Cholesterol Measurement

The T allele of rs780093 is reported to be associated with Total Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Total cholesterol levels (Trans-ethnic initial).

Disease/Trait: Palmitoleic Acid Measurement

The T allele of rs780093 is reported to be associated with Palmitoleic Acid Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with Palmitoleic acid (16:1n-7) levels.

Disease/Trait: Serum Creatinine Measurement

The T allele of rs780093 is reported to be associated with Serum Creatinine Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Glomerular filtration rate (creatinine).

Disease/Trait: Glomerular Filtration Rate

The T allele of rs780093 is reported to be associated with Glomerular Filtration Rate (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Glomerular filtration rate (creatinine).