rs20541 is a G/A polymorphism in the IL13 gene and is associated with IgE levels.
The AA genotype was significantly related to an increased risk of eczema (OR=2.38) [R].
The ''A'' allele was associated with increased odds of allergic rhinitis (AR) in mixed age groups [R].
Compared with the GG genotype, the AA genotype, was significantly positively related to the risk of rhinoconjunctivitis: the adjusted odds ratio was 1.65 [R].
The ''A'' allele was significantly associated with asthma [R].
''A'' allele had a reduced risk of colorectal cancer (CRC) (P(trend) = 0.02) [R].
The ''A'' allele was significantly associated with increased eosinophil count (P < .011) and increased serum total IgE (P < .054) [R].
The ''G'' allele was susceptible to psoriasis, while the A allele was protective [R].
''A'' allele was significantly associated with protection from psoriatic arthritis (PsA) [R].
''A'' allele showed association with development of non-atopic hand eczema (OR = 3.38) [R].
''A'' allele was most strongly associated with susceptibility to Chronic obstructive pulmonary disease (COPD) [R].
The minor allele ''A'' is the risk allele for asthma but the protective allele for psoriasis [R].
GA/AA genotypes were significantly associated with reduced risk for glioma (OR = 0.85, GA/AA vs. GG) [R].
The GA genotype was significantly related to a decreased risk of hepatocellular carcinoma (HCC) (OR = 0.54, 95%) [R].
''G'' allele increased the risk of disease progression to late-stage schistosomiasis (OR = 1.46, p = 0.035), whereas ''A'' allele showed a protective role against development of late-stage schistosomiasis (OR = 0.61, p = 0.002) [R].