The Function of AFF3
Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double-stranded DNA.
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Protein names
Recommended name:
AF4/FMR2 family member 3Alternative name(s):
Lymphoid nuclear protein related to AF4Protein LAF-4
- RS10209110 (AFF3) ??
- RS11676922 (AFF3) ??
- RS4851266 (AFF3) ??
- RS6712515 (AFF3) ??
- RS7583877 (AFF3) ??
- RS7601137 (AFF3) ??
- RS9653442 (AFF3) ??
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Top Gene-Substance Interactions
Substances That Increase AFF3
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Substances That Decrease AFF3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Preferentially expressed in lymphoid tissues, highest levels being found in the thymus.
Molecular Function:
Biological Processes:
- Embryonic Hindlimb Morphogenesis
- Regulation Of Transcription, Dna-Templated
- Response To Tumor Necrosis Factor
- Transcription, Dna-Templated