rs401681 is a SNP in the CLPTM1-like CLPTM1 gene.

The following studies span several types of cancer, and over 30,000 cases and 45,000 controls.

deCODE Prostate-Specific Antigen


[PMID 23393597] Replication and Predictive Value of SNPs Associated with Melanoma and Pigmentation Traits in a Southern European Case-Control Study


[PMID 24039754] The impact of polymorphic variations in the 5p15, 6p12, 6p21 and 15q25 Loci on the risk and prognosis of portuguese patients with non-small cell lung cancer


[PMID 24386361] Genetic Variant rs401681 at 5p15.33 Modifies Susceptibility to Lung Cancer but Not Esophageal Squamous Cell Carcinoma


[PMID 24577890] Association between CLPTM1L-TERT rs401681 polymorphism and pancreatic cancer risk among Chinese Han population


[PMID 22893025] Association between TERT-CLPTM1L rs401681[C] allele and NMSC cancer risk: a meta-analysis including 45,184 subjects.


[PMID 23433592] Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer--a case-control study in a Chinese population.


[PMID 23535824] Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.


[PMID 24761905] Genetic Variations in TERT-CLPTM1L Genes and Risk of Lung Cancer in a Chinese Population


[PMID 24861918] Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer: a case-control study in northeast Chinese male population


[PMID 24907075] Association between CLPTM1L polymorphisms (rs402710 and rs401681) and lung cancer susceptibility: evidence from 27 case-control studies


[PMID 25007268] TERT-CLPTM1L Rs401681 C>T Polymorphism Was Associated with a Decreased Risk of Esophageal Cancer in a Chinese Population


[PMID 24615522] Quantitative assessment of common genetic variants on chromosome 5p15 and lung cancer risk


[PMID 25159867] Common variants modify the age of onset for basal cell carcinomas in Gorlin syndrome


[PMID 25457634] Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk


[PMID 25837821] Inherited genetic variants associated with occurrence of multiple primary melanoma


[PMID 26304507] Association of gastrointestinal gland cancer susceptibility loci with esophageal carcinoma among the Chinese Han population: a case-control study


[PMID 26590902] Fine-mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci

rs401681

Parent Gene: CLPTM1L, TERT

Importance: 5
Less common allele: T = 41%
More common allele: C = 59%
My Genotype: Log In
Risk Allele: G, A, C, C, C, T, C, C, C

Disease/Trait: Lung Carcinoma

The G allele of rs401681 is reported to be associated with Lung Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Lung cancer.

Disease/Trait: Melanoma

The A allele of rs401681 is reported to be associated with Melanoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Melanoma.

Disease/Trait: Bladder Carcinoma

The C allele of rs401681 is reported to be associated with Bladder Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Bladder cancer.

Disease/Trait: Prostate Specific Antigen Measurement

The C allele of rs401681 is reported to be associated with Prostate Specific Antigen Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Serum prostate-specific antigen levels.

Disease/Trait: Bladder Carcinoma

The C allele of rs401681 is reported to be associated with Bladder Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Bladder cancer.

Disease/Trait: Pancreatic Carcinoma

The T allele of rs401681 is reported to be associated with Pancreatic Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pancreatic cancer.

Disease/Trait: Basal Cell Carcinoma

The C allele of rs401681 is reported to be associated with Basal Cell Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Basal cell carcinoma.

Disease/Trait: Basal Cell Carcinoma

The C allele of rs401681 is reported to be associated with Basal Cell Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Basal cell carcinoma.

Disease/Trait: Nasopharyngeal Neoplasm

rs401681 is associated with Nasopharyngeal Neoplasm (R) . It is reported to increased association with Nasopharyngeal carcinoma. No specific risk allele was identified in the study.

Disease/Trait: Pancreatic Carcinoma

rs401681 is associated with Pancreatic Carcinoma (R) . It is reported to increased association with Pancreatic cancer. No specific risk allele was identified in the study.

Disease/Trait: Basal Cell Carcinoma

The C allele of rs401681 is reported to be associated with Basal Cell Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Basal cell carcinoma.