T = increased risk for celiac disease.

In a study of non-HLA SNP associations of 1600 celiac disease patients, this SNP was considered one of the most significant (OR =1.19,  p=1.33x10e-7) [R].

Individuals with the T allele should be cautious about gluten.

rs3184504

Parent Gene: SH2B3

Importance: 5
Less common allele: T = 15%
More common allele: C = 85%
My Genotype: Log In
Risk Allele: T, T, T, T, T, T, T, T, T, T, C, C, C, C, C, T, T, T, C, C, T, T, T

Disease/Trait: Eosinophil Count

The T allele of rs3184504 is reported to be associated with Eosinophil Count (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Eosinophil counts (EA).

Disease/Trait: Systolic Blood Pressure

The T allele of rs3184504 is reported to be associated with Systolic Blood Pressure (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Systolic blood pressure.

Disease/Trait: Diastolic Blood Pressure

The T allele of rs3184504 is reported to be associated with Diastolic Blood Pressure (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Diastolic blood pressure.

Disease/Trait: Type I Diabetes Mellitus

rs3184504 is associated with Type I Diabetes Mellitus (R) . It is reported to association with Type 1 diabetes. No specific risk allele was identified in the study.

Disease/Trait: Diastolic Blood Pressure

The T allele of rs3184504 is reported to be associated with Diastolic Blood Pressure (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Diastolic blood pressure.

Disease/Trait: Coronary Heart Disease

The T allele of rs3184504 is reported to be associated with Coronary Heart Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Coronary heart disease.

Disease/Trait: Hypothyroidism

The T allele of rs3184504 is reported to be associated with Hypothyroidism (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Hypothyroidism.

Disease/Trait: Rheumatoid Arthritis

The T allele of rs3184504 is reported to be associated with Rheumatoid Arthritis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Rheumatoid arthritis.

Disease/Trait: Autoimmune Hepatitis

rs3184504 is associated with Autoimmune Hepatitis . It is reported to increased association with Autoimmune hepatitis type-1. No specific risk allele was identified in the study.

Disease/Trait: Blood Metabolite Measurement

The T allele of rs3184504 is reported to be associated with Blood Metabolite Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Blood metabolite levels (kynurenine).

Disease/Trait: Platelet Count

The T allele of rs3184504 is reported to be associated with Platelet Count (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Platelet count.

Disease/Trait: Hemoglobin Measurement

The T allele of rs3184504 is reported to be associated with Hemoglobin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Red blood cell traits (EA, Hgb).

Disease/Trait: Inflammatory Bowel Disease

rs3184504 is associated with Inflammatory Bowel Disease (R) . It is reported to association with Inflammatory bowel disease (EA). No specific risk allele was identified in the study.

Disease/Trait: Colorectal Cancer

The C allele of rs3184504 is reported to be associated with Colorectal Cancer (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Colorectal cancer (EA).

Disease/Trait: Colorectal Cancer

The C allele of rs3184504 is reported to be associated with Colorectal Cancer (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Colorectal cancer.

Disease/Trait: Beta-2 Microglobulin Measurement

The C allele of rs3184504 is reported to be associated with Beta-2 Microglobulin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Beta-2 microglubulin plasma levels.

Disease/Trait: Platelet Count

The C allele of rs3184504 is reported to be associated with Platelet Count (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Platelet count.

Disease/Trait: Colorectal Cancer

The C allele of rs3184504 is reported to be associated with Colorectal Cancer (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Colorectal or endometrial cancer (same direction).

Disease/Trait: Endometrial Neoplasm

The C allele of rs3184504 is reported to be associated with Endometrial Neoplasm (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Colorectal or endometrial cancer (same direction).

Disease/Trait: Coronary Artery Disease

The T allele of rs3184504 is reported to be associated with Coronary Artery Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Coronary artery disease.

Disease/Trait: Diastolic Blood Pressure

The T allele of rs3184504 is reported to be associated with Diastolic Blood Pressure (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Diastolic blood pressure (EA).

Disease/Trait: Sclerosing Cholangitis

The T allele of rs3184504 is reported to be associated with Sclerosing Cholangitis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Primary sclerosing cholangitis.

Disease/Trait: Lung Carcinoma

The C allele of rs3184504 is reported to be associated with Lung Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Colorectal Cancer

The C allele of rs3184504 is reported to be associated with Colorectal Cancer (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Breast Carcinoma

The C allele of rs3184504 is reported to be associated with Breast Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Prostate Carcinoma

The C allele of rs3184504 is reported to be associated with Prostate Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Ovarian Carcinoma

The C allele of rs3184504 is reported to be associated with Ovarian Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Lung Adenocarcinoma

The C allele of rs3184504 is reported to be associated with Lung Adenocarcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Estrogen-Receptor Negative Breast Cancer

The C allele of rs3184504 is reported to be associated with Estrogen-receptor Negative Breast Cancer (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Ovarian Endometrioid Carcinoma

The C allele of rs3184504 is reported to be associated with Ovarian Endometrioid Carcinoma . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Ovarian Serous Carcinoma

The C allele of rs3184504 is reported to be associated with Ovarian Serous Carcinoma . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Squamous Cell Lung Carcinoma

The C allele of rs3184504 is reported to be associated with Squamous Cell Lung Carcinoma . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer.

Disease/Trait: Lung Carcinoma

The C allele of rs3184504 is reported to be associated with Lung Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Colorectal Cancer

The C allele of rs3184504 is reported to be associated with Colorectal Cancer (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Breast Carcinoma

The C allele of rs3184504 is reported to be associated with Breast Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Prostate Carcinoma

The C allele of rs3184504 is reported to be associated with Prostate Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Ovarian Carcinoma

The C allele of rs3184504 is reported to be associated with Ovarian Carcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Lung Adenocarcinoma

The C allele of rs3184504 is reported to be associated with Lung Adenocarcinoma (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Estrogen-Receptor Negative Breast Cancer

The C allele of rs3184504 is reported to be associated with Estrogen-receptor Negative Breast Cancer (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Ovarian Endometrioid Carcinoma

The C allele of rs3184504 is reported to be associated with Ovarian Endometrioid Carcinoma . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Ovarian Serous Carcinoma

The C allele of rs3184504 is reported to be associated with Ovarian Serous Carcinoma . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Squamous Cell Lung Carcinoma

The C allele of rs3184504 is reported to be associated with Squamous Cell Lung Carcinoma . Your genotype was not identified for this SNP so we are unable to comment on your association with Cancer (pleiotropy) (subset analysis).

Disease/Trait: Coronary Heart Disease

The T allele of rs3184504 is reported to be associated with Coronary Heart Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Coronary artery disease.

Disease/Trait: Tonsillectomy Risk Measurement

rs3184504 is associated with Tonsillectomy Risk Measurement . It is reported to increased association with Tonsillectomy. No specific risk allele was identified in the study.

Disease/Trait: Hemoglobin Measurement

rs3184504 is associated with Hemoglobin Measurement (R) . It is reported to association with Hemoglobin levels. No specific risk allele was identified in the study.

Disease/Trait: Fibrinogen Measurement

rs3184504 is associated with Fibrinogen Measurement (R) . It is reported to have a 0.0066 unit increase on Fibrinogen levels. No specific risk allele was identified in the study.

Disease/Trait: Eosinophil Count

The T allele of rs3184504 is reported to be associated with Eosinophil Count (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with White blood cell count (eosinophil).

Disease/Trait: Type I Diabetes Mellitus

The T allele of rs3184504 is reported to be associated with Type I Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 1 diabetes.