rs16891982 is a SNP in the SLC45A2 gene. It is strongly associated with malignant melanoma (MM) (OR, 0.41; P=0.008) [R1, R2].

It was also highly associated with human hair color and skin pigmentation (P = 0.036 for hair color (black to blonde), P = 0.016 for tanning ability, and P = 0.0009 for skin color) [R].

Brown eye color is predicted for the C/C gneotype plus A/A or G/A at rs12913832, green eye color is predcited by C/Cc genotype plus G/G at rs12913832 [R].

The ''C'' allele was strongly associated with melanoma and pigmentation traits (OR 0.51; P = 0.001) [R].

 

rs16891982

Parent Gene: SLC45A2

Importance: 4
Less common allele: G = 28%
More common allele: C = 72%
My Genotype: Log In
Risk Allele: C, C, C, G

Disease/Trait: Eye Color

The C allele of rs16891982 is reported to be associated with Eye Color (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Eye color (eye color).

Disease/Trait: Hair Color

rs16891982 is associated with Hair Color (R) . It is reported to association with Hair color (hair color). No specific risk allele was identified in the study.

Disease/Trait: Skin Pigmentation

The C allele of rs16891982 is reported to be associated with Skin Pigmentation (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Skin pigmentation.

Disease/Trait: Hair Color

rs16891982 is associated with Hair Color (R) . It is reported to increased association with Black vs. non-black hair color. No specific risk allele was identified in the study.

Disease/Trait: Skin Sensitivity To Sun

The C allele of rs16891982 is reported to be associated with Skin Sensitivity To Sun (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Skin sensitivity to sun.

Disease/Trait: Squamous Cell Carcinoma

rs16891982 is associated with Squamous Cell Carcinoma (R) . It is reported to increased association with Squamous cell carcinoma. No specific risk allele was identified in the study.

Disease/Trait: Synophrys Measurement

rs16891982 is associated with Synophrys Measurement . It is reported to have a 0.14800000000000002 unit decrease on Monobrow. No specific risk allele was identified in the study.

Disease/Trait: Melanoma

rs16891982 is associated with Melanoma (R) . It is reported to increased association with Melanoma. No specific risk allele was identified in the study.

Disease/Trait: Skin Pigmentation

The G allele of rs16891982 is reported to be associated with Skin Pigmentation (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Skin pigmentation.