The Minor "A" allele is associated with:

  • Increased oxidative stress within the body
  • Increased risk for some cancers such as colorectal cancer (AA).
  • Slower metabolizer of drugs
  • Lower levels of MDR1 protein.

The Major "T" allele is associated with:

  • Lower chance of successful antiviral treatment. 

rs1045642

Parent Gene: MDR1

Importance: 3
Less common allele: A = 40%
More common allele: G = 60%
My Genotype: Log In