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  3. PTHLH

PTHLH (Parathyroid hormone like hormone)

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The Function of PTHLH

Osteostatin is a potent inhibitor of osteoclastic bone resorption.

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Protein names

Recommended name:

Parathyroid hormone-related protein

Short name:

PLP

Alternative name(s):

PTH-rP
PTHrP
Parathyroid hormone-like protein
PTHrP[107-139]

PTHLH SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10771399 (PTHLH) ??
  2. RS10843026 (PTHLH) ??
  3. RS12371778 (PTHLH) ??
  4. RS258401 (PTHLH) ??
  5. RS258415 (PTHLH) ??
  6. RS4420311 (PTHLH) ??
  7. RS7953528 (PTHLH) ??
  8. RS805512 (PTHLH) ??

Top Gene-Substance Interactions

PTHLH Interacts with These Diseases

Disease Score

Substances That Increase PTHLH

Substances Interaction Organism Category

Substances That Decrease PTHLH

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • GR
  • GR-alpha
  • GR-beta
  • CREB
  • AP-1
  • c-Jun
  • deltaCREB
  • Sp1
  • c-Rel
  • AP-2gamma

Tissue specificity:

Ubiquitous. Also expressed in the mammary gland.

Gene Pathways:

  • Signal Transduction

Molecular Function:

  • Hormone Activity
  • Peptide Hormone Receptor Binding

Biological Processes:

  • Adenylate Cyclase-Activating G-Protein Coupled Receptor Signaling Pathway
  • Camp Metabolic Process
  • Cell-Cell Signaling
  • Epidermis Development
  • Female Pregnancy
  • Negative Regulation Of Cell Proliferation
  • Negative Regulation Of Chondrocyte Differentiation
  • Osteoblast Development
  • Positive Regulation Of Camp Biosynthetic Process
  • Positive Regulation Of Cell Proliferation
  • Regulation Of Gene Expression
  • Skeletal System Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| PLP| A306_09998| Anapl_01516| AS27_14165| AS28_13018| BDE2| CB1_002578025| D623_10027363| EGK_03491| H920_07357| HHM| I79_020531| M91_00456| M959_12122| MDA_GLEAN10012582| N301_10157| N302_12173| N303_06027| N306_10717| N307_03082| N308_04014| N309_02143| N310_11975| N311_12331| N312_06240| N320_03110| N321_02093| N322_02149| N324_00932| N325_05673| N327_06850| N328_00636| N330_11141| N332_04034| N333_06884| N334_11375| N335_11304| N336_12627| N339_00956| N340_10067| N341_07886| osteostatin| parathyroid hormone-like hormone| parathyroid hormone-like hormone preproprotein| parathyroid hormone-like peptide| parathyroid hormone-like protein| parathyroid hormone-like related protein| parathyroid hormone-related peptide| parathyroid hormone-related protein| parathyroid hormone-related protein isoform 1 preproprotein| parathyroid-like peptide| PTH-like| PTHR| PTH-related peptide| PTH-related protein| PTH-rP| PTHRP| TREES_T100009622| UY3_04335| Y1Q_021803| Y956_12302| Z169_06964| pthlh

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