The Function of PRL
Prolactin acts primarily on the mammary gland by promoting lactation.
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Protein names
Recommended name:
ProlactinShort name:
PRL- RS1341239 (PRL) ??
- RS4236016 (PRL) ??
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Top Gene-Substance Interactions
PRL Interacts with These Diseases
| Disease | Score |
Substances That Increase PRL
| Substances | Interaction | Organism | Category |
Substances That Decrease PRL
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
- Prolactin Receptor Binding
- Dna Binding
- Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Dna Binding
- Transcriptional Activator Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
- Transcription Factor Activity, Sequence-Specific Dna Binding
- Transcription Factor Binding
Biological Processes:
- Cell Proliferation
- Cell Surface Receptor Signaling Pathway
- Cellular Protein Metabolic Process
- Female Pregnancy
- Jak-Stat Cascade Involved In Growth Hormone Signaling Pathway
- Lactation
- Positive Regulation Of Jak-Stat Cascade
- Regulation Of Multicellular Organism Growth
- Adrenal Gland Development
- Anterior/Posterior Pattern Specification
- Branching Involved In Ureteric Bud Morphogenesis
- Embryonic Hemopoiesis
- Embryonic Limb Morphogenesis
- Embryonic Skeletal System Development
- Negative Regulation Of Neuron Differentiation
- Negative Regulation Of Sequence-Specific Dna Binding Transcription Factor Activity
- Positive Regulation Of Cell Proliferation
- Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
- Proximal/Distal Pattern Formation
- Regulation Of Ossification
- Sex Differentiation
- Somatic Stem Cell Population Maintenance
- Spleen Development
- Steroid Biosynthetic Process
- Thymus Development