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  3. COL5A2

COL5A2 (Collagen type V alpha 2 chain)

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The Function of COL5A2

Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices.

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COL5A2 SNPs

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  1. RS11186 (COL5A2) ??

Top Gene-Substance Interactions

Substances That Increase COL5A2

Substances Interaction Organism Category

Substances That Decrease COL5A2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • c-Myc

Gene Pathways:

  • Signal Transduction
  • Extracellular matrix organization
  • Amoebiasis
  • Protein digestion and absorption

Molecular Function:

  • Extracellular Matrix Structural Constituent
  • Metal Ion Binding

Biological Processes:

  • Cellular Response To Amino Acid Stimulus
  • Collagen Catabolic Process
  • Collagen Fibril Organization
  • Extracellular Matrix Organization
  • Eye Morphogenesis
  • Negative Regulation Of Endodermal Cell Differentiation
  • Ossification
  • Skeletal System Development
  • Skin Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| EDSC| Collagen alpha-2(V) chain| collagen, type V, alpha 2| A306_13700| AB collagen| alpha 2 type V collagen| AS27_08749| AS28_05032| CB1_001183008| collagen alpha-2(V) chain preproprotein| collagen, fetal membrane, A polypeptide| collagen type V alpha 2| D623_10008784| GW7_11684| H920_10640| M91_12673| M959_07764| MDA_GLEAN10023629| N300_13537| N301_02387| N302_09850| N303_01515| N305_02379| N306_03183| N307_05625| N308_05318| N309_09027| N310_01113| N311_03019| N312_03095| N320_11898| N321_04489| N322_13752| N324_01827| N325_03733| N326_02912| N327_10662| N328_06158| N329_12205| N333_09114| N334_05260| N339_02775| N340_13425| PAL_GLEAN10026054| PANDA_007211| procollagen, type V, alpha 2| TREES_T100006552| type II procollagen alpha 1 chain| type V preprocollagen alpha 2 chain| UY3_16678| Y1Q_030055| Y956_03991| Z169_07090| col5a2

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