The Function of COL5A2
Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices.
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- RS11186 (COL5A2) ??
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Top Gene-Substance Interactions
Substances That Increase COL5A2
| Substances | Interaction | Organism | Category |
Substances That Decrease COL5A2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Cellular Response To Amino Acid Stimulus
- Collagen Catabolic Process
- Collagen Fibril Organization
- Extracellular Matrix Organization
- Eye Morphogenesis
- Negative Regulation Of Endodermal Cell Differentiation
- Ossification
- Skeletal System Development
- Skin Development