High Blood Sugar
Anxiety
Gluten Sensitivity
Gut Inflammation
Blood Pressure
IBS
Mood
Insomnia
PTSD
Mood Swings
Overweight
Memory Performance
Sexual Dysfunction
PCOS
Psoriasis
Joint Pain
Attention/ADHD
Chronic Fatigue / Tiredness
Allergies
Asthma
Acne
Tinnitus
Eczema
Food Allergy
Vitamin B6
Vitamin E
Restless Leg Syndrome
Grinding Teeth
Vitamin A
Magnesium
Zinc
Heart Health
Migraines
(High) Cholesterol
Headache
Chronic Pain
Back pain
Shoulder & Neck Pain
Stress
Inflammation
Omega-3 needs
Salt Sensitivity
Endurance
Power performance
Strength
Exercise recovery
Brain Fog
Female Fertility
Longevity
Addiction
Erectile Dysfunction
Male Infertility
MTHFR
Joint Inflammation
GERD
Ulcers
Sleep Apnea
Periodontitis
Varicose Veins
H. pylori
Liver Health
Canker Sores
Gallstones
Kidney Health
Gout
Hair Loss (Male-Pattern Baldness)
Riboflavin
Urticaria
Rosacea
Carpal Tunnel Syndrome
Sinus Congestion
Cavities
Artery Hardening
Vertigo
Vitiligo
Myopia
Indigestion
Excessive Sweating
Testosterone – Males
Yeast infection (Candida)
Endometriosis
Tobacco addiction
Alcohol addiction
Uterine fibroids
Length of menstrual cycle
UTI
OCD
Kidney Stones
Vitamin B12
Vitamin C
Vitamin D
Folate
Iron
Eating Disorders
Bone Health
Hypothyroidism
Hyperthyroidism
Sugar Cravings
Hearing/difficulty problem /Hearing loss
Painful Periods
Palpitations
Hemorrhoids
Hypotension
Bladder Control
Constipation
Appendicitis
Low Blood Sugar
Irregular Periods
Metabolic rate
Visceral fat
Lung Health
Anemia
Calcium
Cognition
Cognitive Decline
Seasonal Low Mood
Vitamin K
Phosphate
HRV
Cluster headaches
Knee Pain
Hip Pain
Selenium
Low back injury
Dyslexia
Cannabis addiction
Histamine Intolerance
Carnitine
Pesticide Sensitivity
Organophosphate Sensitivity
Cadmium
Lead
Melatonin
FSH
T4
T3
High PTH
Potassium
Coenzyme Q10 (CoQ10)
Chromium
Oxalate Sensitivity
Salicylate Sensitivity
Facial Wrinkles
Age Spots
Ligament Rupture (ACL Injury)
Tendon Injury (Tendinopathy)
Omega 6
Omega 6:Omega 3 Ratio
Arachidonic Acid
Oleic Acid
Alpha-Linolenic Acid
EPA
GLA
Linoleic Acid
DHA
Insulin Resistance
Sperm Motility
Homocysteine
C difficile
Pneumonia
EBV Infection
Gastrointestinal Infection
Chronic Bronchitis
Copper
Skin Elasticity
Skin Hydration
Egg allergy
ApoB
GGT
TIBC
Bioavailable Testosterone (Male)
MPV
Chloride
Free T4
Processing Speed
Short-term memory
TMAO
Air pollution sensitivity
Heart Rate
VO2 Max
Flu
Hair graying
Caffeine-Related Sleep Problems
Groin Hernia
Stretch marks
Droopy Eyelids
Strep infection
Dry eyes
Carbohydrate Consumption
Peanut allergy
Heart rate recovery
Muscle recovery
Jaw Disorders
HPV Infection
Acute Bronchitis
Chlamydia
Genital Herpes
Pancreas inflammation
Executive Function
Pyroglutamic acid
Raynaud’s
Liver Scarring
Dandruff
Bioavailable Testosterone (Female)
Shrimp allergy
Haptoglobin
Milk allergy
Beta-Alanine
Taurine
LDL Particle Size
Diarrhea
Snoring
Uric acid
Phenylalanine
Leucine
Glutamine
Valine
Glycine
Alanine
Lysine
Arginine
Histidine
Tyrosine
Cortisol
DHEAS
Insulin
Prolactin
TSH
Lactate
Ketone Bodies
IL-17A (Th17 Dominance)
Creatine Kinase
Neutrophils
Basophils
Eosinophils
Ferritin
ALT
AST
MCV
Hematocrit
RDW
SHBG
Total Protein
Albumin
MCH
Sodium
MCHC
Alkaline Phosphatase
Monocytes
Ghrelin
IL10 (Th2)
IL-6 (Th2 and Th17)
Iodine
Chili Pepper sensitivity
COMT
DRD2 (Dopamine)
Lectin Sensitivity
Thiamine
Biotin
Mold Sensitivity (Foodborne)
Chronic Lyme
BDNF
Glyphosate sensitivity
BPA Sensitivity
Pregnenolone
Luteinizing Hormone (LH)
Growth Hormone
IgA
Molybdenum
Sensitivity to Dairy (IgG Casein)
Telomere Length
Serotonin (5HIAA)
Non-Celiac Gluten Sensitivity (IgG Gliadin)
Manganese
Klotho
Mold Sensitivity (Airborne)
Amylase
Lipase
Low Sperm Count
Tryptophan
Methionine
Glutamate
Proline
Blood Calcium
Hypertriglyceridemia
HDL Cholesterol
HbA1c
Hemoglobin
Total Cholesterol
LDL Cholesterol
IGF1
Fasting Glucose
Bilirubin (total)
White blood cell count
Red blood cell count
Platelets
eGFR
Creatinine
Estradiol
Neuroticism
Sleep Quality
Lactose Intolerance
Saturated fat
Optimal diet
Unsaturated fat
Achilles tendon injury
Deep sleep
Fat
Response to Stress
Leadership
Ankle injury
Creativity
Hoarding
Protein
Optimal Exercise
Knee Injury
Rotator cuff injury
Extraversion
Risk-Taking
Happiness
Daytime Sleepiness
Morningness
Time spent watching TV
Disliking cilantro
Alcohol Sensitivity
Response to Caffeine
Snacking
Weight Regain
Sleep movement
Wearing glasses or contacts
Educational Attainment
Bitter Taste Sensitivity
Agreeableness
Aggression
Conscientiousness
Openness to experience
Physical activity
Caffeine-Related Anxiety
Naps
SelfDecode uses the only scientifically validated genetic prediction technology for consumers. Read more
rs13107325
Chromosome
: 4 , Position: 102267552
Most conditions are affected by anywhere from hundreds to millions of
genetic variants (SNPs). A single SNP usually has a minor contribution to
a person’s overall genetic risk for a certain condition. That is why you
shouldn't consider or act on a SNP in isolation. Instead, we use SNPs to
determine polygenic risk scores (PRSs), which are the basis of most health
reports.
Reference Allele: C
Alternative Alleles:
A, T
Traits
| Trait | Variant | Impact | PMID | Author (year) |
|---|---|---|---|---|
| Alcohol use disorder (consumption score) | T |
|
Nat Commun | Kranzler HR (2019) |
| Alcohol use disorder | T |
|
Nat Neurosci | Zhou H (2020) |
| General cognitive ability | T |
|
Nat Commun | Davies G (2018) |
| Nucleus accumbens volume | T |
|
Nat Genet | Satizabal CL (2019) |
| Alcohol consumption (heavy vs. light/non-drinkers) | T |
|
Sci Adv | Thompson A (2020) |
| Impedance of leg (right) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Impedance of leg (left) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Systolic blood pressure [EA, initial] | T |
|
Hypertension | Wain LV (2017) |
| Diastolic blood pressure [EA, initial] | T |
|
Hypertension | Wain LV (2017) |
| Systolic blood pressure [EA] | T |
|
Nat Genet | Hoffmann TJ (2016) |
| Mean arterial pressure | T |
|
Nat Genet | Liu C (2016) |
| Blood pressure [Mean Arterial Pressure] | T |
|
Nat Genet | Wain LV (2011) |
| Diastolic blood pressure | T |
|
Nat Genet | Ehret GB (2016) |
| Systolic blood pressure | T |
|
Nat Genet | Giri A (2018) |
| Liver fibrosis and steatohepatitis severity (MRI cT1 measure) | T |
|
J Hepatol | Parisinos CA (2020) |
| Diastolic blood pressure [EA] | T |
|
Nat Genet | Hoffmann TJ (2016) |
| Brain imaging measurements [Imaging-derived phenotype IDP_T1_FAST_ROIs_L_putamen] | T |
|
Nature | Elliott LT (2018) |
| Brain imaging measurements [Imaging-derived phenotype IDP_T1_FAST_ROIs_R_putamen] | T |
|
Nature | Elliott LT (2018) |
| Hip circumference | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Arm fat percentage (left) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Arm fat percentage (right) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Brain imaging measurements [Imaging-derived phenotype IDP_T1_FAST_ROIs_L_ventral_striatum] | T |
|
Nature | Elliott LT (2018) |
| Brain imaging measurements [Imaging-derived phenotype IDP_T1_FAST_ROIs_R_ventral_striatum] | T |
|
Nature | Elliott LT (2018) |
| Hand grip strength (right) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Standing height | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Body mass index (bmi) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| NT-proBNP levels in acute coronary syndrome | T |
|
Hum Mol Genet | Johansson A (2016) |
| Leg fat percentage (right) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Leg fat percentage (left) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Fluid intelligence score | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Sitting height | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Spherical equivalent | T |
|
JAMA Ophthalmol | Han X (2020) |
| Haematocrit percentage | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Cognitive aspects of educational attainment | T |
|
Nat Genet | Demange PA (2021) |
| Anterior thalamic nuclei volume | T |
|
Nat Commun | Elvsashagen T (2021) |
| Lateral thalamic nuclei volume | T |
|
Nat Commun | Elvsashagen T (2021) |
| Alcohol use disorder (consumption score) [EA] | T |
|
Nat Commun | Kranzler HR (2019) |
| Childhood body mass index | T |
|
PLoS Genet | Vogelezang S (2020) |
| HDL cholesterol levels | T |
|
PLoS Med | Richardson TG (2020) |
| HDL cholesterol | T |
|
Nat Genet | Klarin D (2018) |
| Metabolic syndrome | T |
|
Metab Syndr Relat Disord | Lind L (2019) |
| Body mass index [EA, men] | T |
|
PLoS Genet | Graff M (2017) |
| Medication use (agents acting on the renin-angiotensin system) | T |
|
Nat Commun | Wu Y (2019) |
| Apolipoprotein A1 levels | T |
|
PLoS Med | Richardson TG (2020) |
| Gastroesophageal reflux disease | T |
|
Gut | Ong JS (2021) |
| Body mass index [men] | T |
|
PLoS Genet | Graff M (2017) |
| High density lipoprotein cholesterol levels | T |
|
Nat Genet | Hoffmann TJ (2018) |
| High density lipoprotein cholesterol levels [EA] | T |
|
Nat Genet | Hoffmann TJ (2018) |
| Monocyte percentage | T |
|
Unknown journal | UKB Neale v2 (2018) |
| BMI (adjusted for smoking behaviour) [men] | T |
|
Nat Commun | Justice AE (2017) |
| Frequency of consuming six or more units of alcohol | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Leg fat mass (right) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Leg fat mass (left) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Total cholesterol levels | T |
|
Nat Genet | Hoffmann TJ (2018) |
| Cognitive performance | T |
|
Nat Genet | Lee JJ (2018) |
| Male-pattern baldness | T |
|
Nat Commun | Yap CX (2018) |
| Body mass index in physically active individuals [EA] | T |
|
PLoS Genet | Graff M (2017) |
| Intelligence | T |
|
Nat Genet | Savage JE (2018) |
| Body mass index in physically active individuals | T |
|
PLoS Genet | Graff M (2017) |
| Body mass index [EA] | T |
|
PLoS Genet | Graff M (2017) |
| Intelligence (MTAG) | T |
|
Mol Psychiatry | Hill WD (2018) |
| Hematocrit | T |
|
Cell | Vuckovic D (2020) |
| Eosinophill percentage | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Amount of alcohol drunk on a typical drinking day | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Hemoglobin | T |
|
Cell | Vuckovic D (2020) |
| Hemoglobin concentration | T |
|
Cell | Astle WJ (2016) |
| Hemoglobin levels | T |
|
Commun Biol | Oskarsson GR (2020) |
| Type 2 diabetes | T |
|
Nat Genet | Vujkovic M (2020) |
| BMI (adjusted for smoking behaviour) | T |
|
Nat Commun | Justice AE (2017) |
| Haemoglobin concentration | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Cognitive performance (MTAG) [MTAG] | T |
|
Nat Genet | Lee JJ (2018) |
| Risk-taking tendency (4-domain principal component model) | T |
|
Nat Genet | Karlsson Linner R (2019) |
| Waist-to-hip ratio adjusted for BMI | T |
|
Hum Mol Genet | Pulit SL (2018) |
| Eosinophil percentage of white cells | T |
|
Cell | Vuckovic D (2020) |
| Adult body size | T |
|
BMJ | Richardson TG (2020) |
| Cheese intake | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Lung function (FVC) | T |
|
Nat Genet | Shrine N (2019) |
| Alcohol consumption (drinks per week) | T |
|
Nat Genet | Liu M (2019) |
| Educational attainment (MTAG) [MTAG] | T |
|
Nat Genet | Lee JJ (2018) |
| Usual walking pace | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Alcohol consumption (drinks per week) (MTAG) | T |
|
Nat Genet | Liu M (2019) |
| Mean corpuscular volume | T |
|
Cell | Chen MH (2020) |
| LDL cholesterol levels | T |
|
PLoS Med | Richardson TG (2020) |
| Walking pace | T |
|
Commun Biol | Timmins IR (2020) |
| Educational attainment (years of education) | T |
|
Nat Genet | Lee JJ (2018) |
| Platelet distribution width | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Plateletcrit | T |
|
Cell | Vuckovic D (2020) |
| Self-reported math ability | T |
|
Nat Genet | Lee JJ (2018) |
| Sleep duration | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Time spent watching television (tv) | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Alcohol consumption | T |
|
Nat Hum Behav | Evangelou E (2019) |
| Facial ageing | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Red blood cell (erythrocyte) count | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Liver enzyme levels (gamma-glutamyl transferase) | T |
|
Nat Commun | Pazoki R (2021) |
| Urate levels | T |
|
Elife | Sinnott-Armstrong N (2021) |
| Hand grip strength | T |
|
Sci Rep | Tikkanen E (2018) |
| Alcohol use disorder [EA] | T |
|
Nat Commun | Kranzler HR (2019) |
| Arthropathy nos | T |
|
Unknown journal | UKB SAIGE (2018) |
| Balding type 1 | T |
|
Am J Hum Genet | Kichaev G (2018) |
| Body fat percentage | T |
|
Am J Med Genet B Neuropsychiatr Genet | Hubel C (2018) |
| Body fat percentage [male] | T |
|
Am J Med Genet B Neuropsychiatr Genet | Hubel C (2018) |
| Body mass index | T |
|
Am J Hum Genet | Kichaev G (2018) |
| Body mass index (joint analysis main effects and physical activity interaction) | T |
|
PLoS Genet | Graff M (2017) |
| Body mass index (joint analysis main effects and physical activity interaction) [EA, men] | T |
|
PLoS Genet | Graff M (2017) |
| Body mass index (joint analysis main effects and physical activity interaction) [EA] | T |
|
PLoS Genet | Graff M (2017) |
| Body mass index (joint analysis main effects and physical activity interaction) [men] | T |
|
PLoS Genet | Graff M (2017) |
| Body mass index (joint analysis main effects and smoking interaction) | T |
|
Nat Commun | Justice AE (2017) |
| Body mass index (joint analysis main effects and smoking interaction) [men] | T |
|
Nat Commun | Justice AE (2017) |
| Body mass index and systole blood pressure (pairwise) | T |
|
Nat Metab | Huang LO (2021) |
| Brain morphology (MOSTest) | T |
|
Nat Commun | van der Meer D (2020) |
| Brain morphology (min-P) | T |
|
Nat Commun | van der Meer D (2020) |
| Brain region volumes [left accumbens area] | T |
|
Nat Genet | Zhao B (2019) |
| Brain region volumes [right accumbens area] | T |
|
Nat Genet | Zhao B (2019) |
| Brain region volumes [white matter] | T |
|
Nat Genet | Zhao B (2019) |
| Cortical surface area (MOSTest) | T |
|
Nat Commun | van der Meer D (2020) |
| Cortical thickness (MOSTest) | T |
|
Nat Commun | van der Meer D (2020) |
| Crohn's disease | T |
|
Nat Genet | de Lange KM (2017) |
| Decaffeinated coffee (any type) | coffee type | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Diastolic blood pressure x alcohol consumption interaction (2df test) [AA, EA] | T |
|
PLoS One | Feitosa MF (2018) |
| Diastolic blood pressure x alcohol consumption interaction (2df test) [EA] | T |
|
PLoS One | Feitosa MF (2018) |
| Eczema | T |
|
Am J Hum Genet | Kichaev G (2018) |
| Height | T |
|
Am J Hum Genet | Kichaev G (2018) |
| Hypertension | T |
|
Genet Epidemiol | German CA (2019) |
| Left-handedness | T |
|
Nat Hum Behav | Cuellar-Partida G (2020) |
| Leisure sedentary behaviour (television watching) | T |
|
Nat Commun | van de Vegte YJ (2020) |
| Low density lipoprotein cholesterol levels | T |
|
Circ Genom Precis Med | Ripatti P (2020) |
| Low hand grip strength (60 years and older) (EWGSOP) | T |
|
Nat Commun | Jones G (2021) |
| Manganese levels | T |
|
Hum Mol Genet | Ng E (2015) |
| Mean arterial pressure x alcohol consumption interaction (2df test) [EA] | T |
|
PLoS One | Feitosa MF (2018) |
| Muesli | cereal type | T |
|
Unknown journal | UKB Neale v2 (2018) |
| None of the above | blood clot, dvt, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor | T |
|
Unknown journal | UKB Neale v2 (2018) |
| None of the above | vascular/heart problems diagnosed by doctor | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Osteoarthritis | T |
|
Nat Genet | Tachmazidou I (2019) |
| Osteoarthritis | non-cancer illness code, self-reported | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Other arthropathies | T |
|
Unknown journal | UKB SAIGE (2018) |
| Pattern 1 | hair/balding pattern | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Peripheral enthesopathies and allied syndromes | T |
|
Unknown journal | UKB SAIGE (2018) |
| Red blood cell count | T |
|
Am J Hum Genet | Kichaev G (2018) |
| Refractive error | T |
|
Nat Genet | Hysi PG (2020) |
| Schizophrenia | T |
|
Am J Med Genet B Neuropsychiatr Genet | Goes FS (2015) |
| Schizophrenia (MTAG) | T |
|
Transl Psychiatry | Wu Y (2020) |
| Shoulder impingement or rotator cuff tear | T |
|
J Shoulder Elbow Surg | Kim SK (2021) |
| Sleep duration (short sleep) | T |
|
Nat Commun | Dashti HS (2019) |
| Strenuous sports | types of physical activity in last 4 weeks | T |
|
Unknown journal | UKB Neale v2 (2018) |
| Subcortical volume (MOSTest) | T |
|
Nat Commun | van der Meer D (2020) |
| Subcortical volume (min-P) | T |
|
Nat Commun | van der Meer D (2020) |
| Systolic blood pressure x alcohol consumption interaction (2df test) [AA, EA] | T |
|
PLoS One | Feitosa MF (2018) |
| Triglyceride levels | T |
|
Circ Genom Precis Med | Ripatti P (2020) |
| Voxel-wise structural brain imaging measurements [left putamen peak voxel] | T |
|
JAMA Psychiatry | Luo Q (2019) |
| Voxel-wise structural brain imaging measurements [right putamen peak voxel] | T |
|
JAMA Psychiatry | Luo Q (2019) |
| Waist circumference adjusted for body mass index | T |
|
J Allergy Clin Immunol | Zhu Z (2019) |
| Waist-hip ratio | T |
|
Am J Hum Genet | Kichaev G (2018) |
| Youthful appearance (self-reported) | T |
|
J Invest Dermatol | Roberts V (2020) |
Summary
[PMID 19503599] The impact of divergence time on the nature of population structure: an example from Iceland.
[PMID 22078303] Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia.
[PMID 23471855] The genetics of childhood obesity and interaction with dietary macronutrients.
[PMID 26006263] Recent Positive Selection Drives the Expansion of a Schizophrenia Risk Nonsynonymous Variant at SLC39A8 in Europeans
[PMID 25184405] Subclinical psychotic experiences in healthy young adults: associations with stress and genetic predisposition
Population Alleles Frequency
|
ethhicity
frequency
|
A | T |
|---|---|---|
| African/African-American | – | 0.0163 |
| Latino/Admixed American | – | 0.0554 |
| Ashkenazi Jewish | – | 0.1379 |
| East Asian | – | – |
| European | – | 0.0656 |
| Other (population not assigned) | – | 0.0515 |
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