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SLC6A2
SNP Table
| variant | genotype | frequency | risk allele |
|---|---|---|---|
| rs552629380 | |||
| rs11076111 | |||
| rs12232407 | |||
| rs13333066 | |||
| rs1368874679 | |||
| rs17247999 | |||
| rs17307096 | |||
| rs17307291 | |||
| rs17841327 | |||
| rs2242446 | |||
| rs28501300 | |||
| rs28618083 | |||
| rs28665972 | |||
| rs28693487 | |||
| rs3785147 | |||
| rs9937434 | |||
| rs139207409 | |||
| rs147053530 | |||
| rs1532701 | |||
| rs2062723 |
Find on This Page
Summary
This gene encodes a member of the sodium:neurotransmitter symporter family. It is a regulator of norepinephrine homeostasis. Mutations can cause orthostatic intolerance, which causes lightheadedness and fatigue (R).
Protein names
Found in These Blog Articles
GHR Function
Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
More Information
From NCBI Gene:
Orthostatic intolerance
Orthostatic intolerance (OI): Syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. It is associated with postural tachycardia. Plasma norepinephrine concentration is abnormally high.
This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope.
It terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
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