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MC3R
SNP Table
| variant | genotype | frequency | risk allele |
|---|---|---|---|
| rs148382606 | |||
| rs1250533532 | |||
| rs143321797 | |||
| rs3827103 | |||
| rs61735256 | |||
| rs61735259 | |||
| rs760789846 | |||
| rs773530462 | |||
| rs145062060 | |||
| rs147084433 | |||
| rs369920230 | |||
| rs41274722 | |||
| rs764841394 | |||
| rs779044626 | |||
| rs141315125 | |||
| rs142214632 | |||
| rs3746619 | |||
| rs144561833 | |||
| rs190606052 | |||
| rs563417943 |
Find on This Page
Summary
The gene codes for a protein, melanocortin 3 receptor. Mutations are linked to a higher chance of obesity in humans [R].
Protein names
Found in These Blog Articles
GHR Function
Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.
More Information
From NCBI Gene: Body mass index quantitative trait locus 9Mycobacterium tuberculosis, susceptibility to
From NCBI Gene: This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008] From UniProt: Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.
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