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LRP1
SNP Table
| variant | genotype | frequency | risk allele |
|---|---|---|---|
| rs113379328 | |||
| rs1282771476 | |||
| rs139292641 | |||
| rs141795284 | |||
| rs141826184 | |||
| rs143564505 | |||
| rs144804370 | |||
| rs148875245 | |||
| rs149869924 | |||
| rs150795346 | |||
| rs199662511 | |||
| rs200073974 | |||
| rs200890734 | |||
| rs201359830 | |||
| rs34577247 | |||
| rs35890409 | |||
| rs36112771 | |||
| rs369821399 | |||
| rs745453126 | |||
| rs747084009 |
Find on This Page
Summary
The gene codes for a protein, LDL receptor related protein 1. It is processed by furin to form the mature receptor. The protein is responsible for amyloid plaques in Alzheimer patients. Expression decreases with age. It has been found to be of lower levels in brain tissue from Alzheimer patients [R].
Protein names
Found in These Blog Articles
GHR Function
Functions as a receptor for Pseudomonas aeruginosa exotoxin A.
Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.
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