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L3MBTL3
SNP Table
| variant | genotype | frequency | risk allele |
|---|---|---|---|
| rs9388768 | |||
| rs7451021 | |||
| rs1112847 | |||
| rs11390217 | |||
| rs12530176 | |||
| rs1415700 | |||
| rs1415701 | |||
| rs55941023 | |||
| rs57844651 | |||
| rs59084494 | |||
| rs6569646 | |||
| rs6569648 | |||
| rs6899976 | |||
| rs6926186 | |||
| rs72987384 | |||
| rs7740188 | |||
| rs9375694 | |||
| rs9375695 | |||
| rs9375696 | |||
| rs9388766 |
Find on This Page
Summary
The gene codes for a protein, l(3)mbt-like 3 (Drosophila). It is on chromosome 6. The L3MBTL3 gene suppresses Notch, a crucial pathway for the development of hair follicles. One gene variant correlates with male-pattern baldness, likely due to increased L3MBTL3 activity and altered Notch function. [R].
Protein names
Found in These Blog Articles
More Information
The L3MBTL3 gene suppresses the Notch pathway, a crucial modifier of the cell life cycle. This pathway stimulates stem cell multiplication in the hair follicle and promotes hair growth [R, R, R, R].
So far, scientists have mostly researched the role of the L3MBTL3 gene in cancer development. Its link with hair loss is a relatively new discovery, and we have yet to learn about the underlying mechanisms [R].
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