The T (minor) allele is associated with:

  •  Increased risk of developing myelosuppression and diarrhea in colorectal and lung cancer subjects being treated with irinotecan (R). This is because Irinotecan can be toxic to cells if it is not removed properly.

 

rs2622604

Parent Gene: ABCG2

Importance: 2
Less common allele: T = 17%
More common allele: C = 83%
My Genotype: Log In
Risk Allele: T

Disease/Trait: Ldl Peak Particle Diameter Measurement

The T allele of rs2622604 is reported to be associated with Ldl Peak Particle Diameter Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with LDL peak particle diameter (total fat intake interaction).

Disease/Trait: Total Fat Intake Measurement

The T allele of rs2622604 is reported to be associated with Total Fat Intake Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with LDL peak particle diameter (total fat intake interaction).