Mechanism:

  • Decreased or non-functioning CYP2D6 protein (AA)
  • Somewhat decreased CYP2D6 protein (AG)
  • Normal CYP2D6 protein (GG)

rs1065852

Parent Gene: CYP2D6

Importance: 3
Less common allele: A = 24%
More common allele: G = 76%
My Genotype: Log In
Risk Allele:

Disease/Trait: Unipolar Depression

rs1065852 is associated with Unipolar Depression (R) . It is reported to association with Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) (S-DDCT concentration). No specific risk allele was identified in the study.

Disease/Trait: Response To Selective Serotonin Reuptake Inhibitor

rs1065852 is associated with Response To Selective Serotonin Reuptake Inhibitor (R) . It is reported to association with Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) (S-DDCT concentration). No specific risk allele was identified in the study.

Disease/Trait: Unipolar Depression

rs1065852 is associated with Unipolar Depression (R) . It is reported to association with Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) (S-DDCT/S-DCT ratio). No specific risk allele was identified in the study.

Disease/Trait: Response To Selective Serotonin Reuptake Inhibitor

rs1065852 is associated with Response To Selective Serotonin Reuptake Inhibitor (R) . It is reported to association with Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) (S-DDCT/S-DCT ratio). No specific risk allele was identified in the study.