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  3. TLN1

TLN1 (Talin 1)

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The Function of TLN1

Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.

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Protein names

Recommended name:

Talin-1

TLN1 SNPs

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  1. RS4879926 (TLN1) ??

Top Gene-Substance Interactions

TLN1 Interacts with These Diseases

Disease Score

Substances That Increase TLN1

Substances Interaction Organism Category

Substances That Decrease TLN1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

Gene Pathways:

  • Signal Transduction
  • Metabolism of proteins
  • Hemostasis
  • Muscle contraction

Molecular Function:

  • Cadherin Binding Involved In Cell-Cell Adhesion
  • Integrin Binding
  • Lim Domain Binding
  • Structural Constituent Of Cytoskeleton
  • Vinculin Binding

Biological Processes:

  • Cell-Cell Junction Assembly
  • Cell-Substrate Junction Assembly
  • Cortical Actin Cytoskeleton Organization
  • Cytoskeletal Anchoring At Plasma Membrane
  • Ire1-Mediated Unfolded Protein Response
  • Movement Of Cell Or Subcellular Component
  • Muscle Contraction
  • Platelet Aggregation
  • Platelet Degranulation
  • Viral Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| ILWEQ| AS27_01166| AS28_00462| bile acid beta-glucosidase| CB1_001041021| D623_10017874| EGK_07566| GBA2| glucosidase, beta (bile acid) 2| H920_03246| M91_01540| MDA_GLEAN10021602| N302_02970| N303_11228| N305_06074| N307_02209| N308_09828| N310_10271| N320_08903| N334_05796| N339_04911| non-lysosomal glucosylceramidase| PAL_GLEAN10008234| PANDA_007476| talin| talin-1| Talin-2| TLN| TREES_T100010552| UY3_18033| tln1

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