The Function of TLN1
Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
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Protein names
Recommended name:
Talin-1- RS4879926 (TLN1) ??
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Top Gene-Substance Interactions
TLN1 Interacts with These Diseases
| Disease | Score |
Substances That Increase TLN1
| Substances | Interaction | Organism | Category |
Substances That Decrease TLN1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
- Integrin Binding
- Structural Constituent Of Cytoskeleton
- Vinculin Binding
- Lim Domain Binding
- Cadherin Binding Involved In Cell-Cell Adhesion
Biological Processes:
- Platelet Degranulation
- Movement Of Cell Or Subcellular Component
- Muscle Contraction
- Cytoskeletal Anchoring At Plasma Membrane
- Cell-Cell Junction Assembly
- Cell-Substrate Junction Assembly
- Viral Process
- Cortical Actin Cytoskeleton Organization
- Ire1-Mediated Unfolded Protein Response
- Platelet Aggregation