The Function of SQLE
Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway.
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Protein names
Recommended name:
Squalene monooxygenaseShort name:
SEAlternative name(s):
Squalene epoxidase- RS13268726 (SQLE) ??
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Top Gene-Substance Interactions
SQLE Interacts with These Diseases
| Disease | Score |
Substances That Increase SQLE
| Substances | Interaction | Organism | Category |
Substances That Decrease SQLE
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Cellular Aromatic Compound Metabolic Process
- Cholesterol Biosynthetic Process
- Cholesterol Metabolic Process
- Response To Organic Substance
- Sterol Biosynthetic Process