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  3. NPY

NPY (Neuropeptide Y)

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Summary of NPY

The gene codes for a protein, neuropeptide Y. It exhibits some antimicrobial activity [R].

0 users want this gene increased, 0 users want it decreased

The Function of NPY

NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.

Protein names

Recommended name:

Pro-neuropeptide Y [Cleaved into: Neuropeptide Y

Short name:

NPY

Alternative name(s):

Neuropeptide tyrosine
CPON

NPY SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1468271 (NPY) ??
  2. RS16139 (NPY) ??
  3. RS2521634 (NPY) ??
  4. RS28459952 (NPY) ??
  5. RS5574 (NPY) ??

Top Gene-Substance Interactions

NPY Interacts with These Diseases

Disease Score

Substances That Increase NPY

Substances Interaction Organism Category

Substances That Decrease NPY

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • GR
  • GR-alpha
  • GR-beta
  • Egr-1
  • CREB
  • AP-1
  • c-Jun
  • deltaCREB
  • c-Fos
  • YY1

Tissue specificity:

One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.

Gene Pathways:

  • Signal Transduction
  • Neuroactive ligand-receptor interaction
  • Adipocytokine signaling pathway

Molecular Function:

  • Calcium Channel Regulator Activity
  • G-Protein Coupled Receptor Activity
  • G-Protein Coupled Receptor Binding
  • Neuropeptide Hormone Activity
  • Receptor Binding

Biological Processes:

  • Adult Feeding Behavior
  • Antibacterial Humoral Response
  • Antifungal Humoral Response
  • Behavior
  • Blood Circulation
  • Calcium Ion Transport
  • Cell Proliferation
  • Central Nervous System Neuron Development
  • Cerebral Cortex Development
  • Chemical Synaptic Transmission
  • Defense Response To Gram-Negative Bacterium
  • Defense Response To Gram-Positive Bacterium
  • Digestion
  • Feeding Behavior
  • G-Protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
  • Innate Immune Response
  • Movement Of Cell Or Subcellular Component
  • Neuron Projection Development
  • Neuropeptide Signaling Pathway
  • Positive Regulation Of Appetite
  • Regulation Of Appetite
  • Regulation Of Blood Pressure
  • Response To Yeast
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_12831| AS27_03411| AS28_05459| CB1_000406001| D623_10031705| EGK_13849| GW7_05685| H920_07026| I79_004427| M959_00254| N300_01056| N301_06466| N302_15367| N303_12208| N305_02605| N307_09437| N309_08591| N310_02132| N311_07447| N312_13516| N322_10490| N324_10936| N325_03551| N326_10491| N327_02004| N328_03896| N330_13591| N331_10180| N332_00481| N333_09439| N334_12142| N335_02643| N339_11183| N340_11221| neuropeptide Y2| NPY02| NPY2| npy-a| npy-b| PAL_GLEAN10021834| PANDA_000679| prepro-neuropeptide Y| prepronpy| Pro-neuropeptide Y| pro-neuropeptide Y-like protein| pro-neuropeptide Y preproprotein| pyy4| RATNPY| RATNPY02| TREES_T100013633| xnpy| Y1Q_020388| Y956_04212| Z169_16325| npy

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