Summary of NPY
The gene codes for a protein, neuropeptide Y. It exhibits some antimicrobial activity [R].
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The Function of NPY
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Protein names
Recommended name:
Pro-neuropeptide Y [Cleaved into: Neuropeptide YShort name:
NPYAlternative name(s):
Neuropeptide tyrosineCPON
- RS1468271 (NPY) ??
- RS16139 (NPY) ??
- RS2521634 (NPY) ??
- RS28459952 (NPY) ??
- RS5574 (NPY) ??
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Top Gene-Substance Interactions
NPY Interacts with These Diseases
| Disease | Score |
Substances That Increase NPY
| Substances | Interaction | Organism | Category |
Substances That Decrease NPY
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.
Gene Pathways:
Molecular Function:
- G-Protein Coupled Receptor Binding
- G-Protein Coupled Receptor Activity
- Receptor Binding
- Neuropeptide Hormone Activity
- Calcium Channel Regulator Activity
Biological Processes:
- Response To Yeast
- Calcium Ion Transport
- Movement Of Cell Or Subcellular Component
- G-Protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
- Neuropeptide Signaling Pathway
- Chemical Synaptic Transmission
- Digestion
- Behavior
- Feeding Behavior
- Blood Circulation
- Regulation Of Blood Pressure
- Cell Proliferation
- Adult Feeding Behavior
- Antibacterial Humoral Response
- Antifungal Humoral Response
- Central Nervous System Neuron Development
- Cerebral Cortex Development
- Neuron Projection Development
- Regulation Of Appetite
- Positive Regulation Of Appetite
- Innate Immune Response
- Defense Response To Gram-Negative Bacterium
- Defense Response To Gram-Positive Bacterium