Summary of NPY
The gene codes for a protein, neuropeptide Y. It exhibits some antimicrobial activity [R].
0 users want this gene increased,
0 users want it decreased
The Function of NPY
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Protein names
Recommended name:
Pro-neuropeptide Y [Cleaved into: Neuropeptide YShort name:
NPYAlternative name(s):
Neuropeptide tyrosineCPON
- RS1468271 (NPY) ??
- RS16139 (NPY) ??
- RS2521634 (NPY) ??
- RS28459952 (NPY) ??
- RS5574 (NPY) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
NPY Interacts with These Diseases
| Disease | Score |
Substances That Increase NPY
| Substances | Interaction | Organism | Category |
Substances That Decrease NPY
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.
Gene Pathways:
Molecular Function:
- Calcium Channel Regulator Activity
- G-Protein Coupled Receptor Activity
- G-Protein Coupled Receptor Binding
- Neuropeptide Hormone Activity
- Receptor Binding
Biological Processes:
- Adult Feeding Behavior
- Antibacterial Humoral Response
- Antifungal Humoral Response
- Behavior
- Blood Circulation
- Calcium Ion Transport
- Cell Proliferation
- Central Nervous System Neuron Development
- Cerebral Cortex Development
- Chemical Synaptic Transmission
- Defense Response To Gram-Negative Bacterium
- Defense Response To Gram-Positive Bacterium
- Digestion
- Feeding Behavior
- G-Protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
- Innate Immune Response
- Movement Of Cell Or Subcellular Component
- Neuron Projection Development
- Neuropeptide Signaling Pathway
- Positive Regulation Of Appetite
- Regulation Of Appetite
- Regulation Of Blood Pressure
- Response To Yeast