Summary of IL3
The Function of IL3
This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
Protein names
Recommended name:
Interleukin-3Short name:
IL-3Alternative name(s):
Hematopoietic growth factorMast cell growth factor
MCGF
Multipotential colony-stimulating factor
P-cell-stimulating factor
- RS2073506 (IL3) ??
- RS3091338 (IL3) ??
- RS40401 (IL3) ??
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Top Gene-Substance Interactions
IL3 Interacts with These Diseases
| Disease | Score |
Substances That Increase IL3
| Substances | Interaction | Organism | Category |
Substances That Decrease IL3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Activated T-cells, mast cells, natural killer cells.
Gene Pathways:
Molecular Function:
- Protein Tyrosine Kinase Activity
- Ras Guanyl-Nucleotide Exchange Factor Activity
- Cytokine Activity
- Interleukin-3 Receptor Binding
Biological Processes:
- Mapk Cascade
- Positive Regulation Of Myeloid Leukocyte Differentiation
- Immune Response
- Cell-Cell Signaling
- Nervous System Development
- Positive Regulation Of Cell Proliferation
- Cytokine-Mediated Signaling Pathway
- Embryonic Hemopoiesis
- Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein
- Positive Regulation Of Dna Replication
- Positive Regulation Of Peptidyl-Tyrosine Phosphorylation
- Positive Regulation Of Mast Cell Proliferation