• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. HRH1

HRH1 (Histamine receptor H1)

Loading...

The Function of HRH1

In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Histamine H1 receptor

Short name:

H1R

Alternative name(s):

HH1R

HRH1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS4684059 (HRH1) ??
  2. RS7651620 (HRH1) ??

Top Gene-Substance Interactions

HRH1 Interacts with These Diseases

Disease Score

Substances That Increase HRH1

Substances Interaction Organism Category

Substances That Decrease HRH1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • AhR

Gene Pathways:

  • Signal Transduction
  • Neuroactive ligand-receptor interaction
  • Calcium signaling pathway

Molecular Function:

  • G-Protein Coupled Receptor Activity
  • Histamine Receptor Activity

Biological Processes:

  • Cellular Response To Histamine
  • Eosinophil Chemotaxis
  • G-Protein Coupled Receptor Signaling Pathway
  • Inflammatory Response
  • Inositol Phosphate-Mediated Signaling
  • Memory
  • Modulation Of Synaptic Transmission
  • Phospholipase C-Activating G-Protein Coupled Receptor Signaling Pathway
  • Positive Regulation Of Inositol Trisphosphate Biosynthetic Process
  • Positive Regulation Of Vasoconstriction
  • Regulation Of Synaptic Plasticity
  • Regulation Of Vascular Permeability
  • Regulation Of Vasoconstriction
  • Visual Learning

Drug Bank:

  • Alimemazine
  • Benzatropine
  • Chlorphenamine
  • Dimetindene
  • Mepyramine
  • Alcaftadine
  • Amoxapine
  • Antazoline
  • Aripiprazole
  • Asenapine
  • Astemizole
  • Azelastine
  • Bepotastine
  • Betahistine
  • Brompheniramine
  • Buclizine
  • Butriptyline
  • Carbinoxamine
  • Cariprazine
  • Cetirizine
  • Chlorcyclizine
  • Chloropyramine
  • Chlorpromazine
  • Chlorprothixene
  • Cinnarizine
  • Clemastine
  • Clofedanol
  • Clozapine
  • Cyclizine
  • Desipramine
  • Desloratadine
  • Dexbrompheniramine
  • Dimenhydrinate
  • Diphenhydramine
  • Diphenylpyraline
  • Doxepin
  • Emedastine
  • Epinastine
  • Escitalopram
  • Fexofenadine
  • Flunarizine
  • Hydroxyzine
  • Iloperidone
  • Imipramine
  • Isothipendyl
  • Ketotifen
  • Levocabastine
  • Levocetirizine
  • Loxapine
  • Maprotiline
  • Meclizine
  • Mequitazine
  • Methotrimeprazine
  • Olopatadine
  • Paliperidone
  • Zuclopenthixol
  • Mirtazapine
  • Nortriptyline
  • Olanzapine
  • Phenindamine
  • Pheniramine
  • Promazine
  • Promethazine
  • Propiomazine
  • Quetiapine
  • Risperidone
  • Trazodone
  • Trimipramine
  • Tripelennamine
  • Triprolidine
  • Ziprasidone
  • Aceprometazine
  • Amitriptyline
  • Azatadine
  • Bromodiphenhydramine
  • Citalopram
  • Cyproheptadine
  • Doxylamine
  • Histamine Phosphate
  • Loratadine
  • Methdilazine
  • Mianserin
  • Orphenadrine
  • Tolazoline
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| H1| 7 transmembrane receptor| A306_07842| AS27_00385| AS28_07530| Bordetella pertussis induced histamine sensitization| Bphs| CB1_099732003| GW7_20149| H1R| H1-R| H920_00802| HH1R| Hir| hisH1| Hisr| histamine H1 receptor| histamine receptor H 1| histamine receptor H1-like protein| histamine receptor, subclass H1| histamine receptor subtype H1| M959_11311| MDA_GLEAN10023739| N300_10955| N301_14225| N302_07210| N303_00451| N305_01569| N306_13206| N307_08328| N308_01922| N309_03260| N310_10851| N311_08787| N312_07960| N320_08655| N321_06604| N322_09859| N324_07541| N325_03673| N326_08595| N327_07885| N328_11073| N329_11415| N330_10521| N331_08469| N332_11799| N334_04918| N335_04561| N336_12442| N339_08912| N340_11140| N341_05768| PAL_GLEAN10022295| PANDA_020856| TREES_T100019839| Y1Q_027107| Y956_05367| Z169_12619| hrh1

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved