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  3. HBG2

HBG2 (Hemoglobin subunit gamma 2)

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The Function of HBG2

Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.

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Protein names

Recommended name:

Hemoglobin subunit gamma-2

Alternative name(s):

Gamma-2-globin
Hb F Ggamma
Hemoglobin gamma-2 chain
Hemoglobin gamma-G chain

Top Gene-Substance Interactions

HBG2 Interacts with These Diseases

Disease Score

Substances That Increase HBG2

Substances Interaction Organism Category

Substances That Decrease HBG2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • p53
  • IRF-1
  • Meis-1
  • TBP
  • GATA-1
  • FOXF2
  • TFIID
  • Meis-1b
  • c-Myb

Tissue specificity:

Red blood cells.

Gene Pathways:

  • Metabolic pathways
  • Hemostasis
  • Galactose metabolism
  • Starch and sucrose metabolism

Developmental stage:

Expressed until four or five weeks after birth.

Molecular Function:

  • Heme Binding
  • Iron Ion Binding
  • Oxygen Binding
  • Oxygen Transporter Activity

Biological Processes:

  • Blood Coagulation
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| hbb2| HBG1| hemoglobin, gamma A| hemoglobin, gamma G| gamma-1-globin| hemoglobin gamma-1 chain| hemoglobin gamma-2 chain| hemoglobin gamma-G chain| hemoglobin subunit gamma-1| hemoglobin subunit gamma-2| abnormal hemoglobin| adult b2 globin| AGLU4| alpha-glucosidase| alpha glucosidase 4| beta-3 globin| EGK_06584| gamma-2-globin| Gamma-globin| gamma globin 2| GB20070| G-gamma globin| G-gamma globin Paulinia| hb F Ggamma| HBG| HBG2_1| hbg2-a| hbg2-b| HBG-T1| Hemoglobin beta-3| hemoglobin gamma-A chain| Hemoglobin gamma chain| hemoglobin subunit gamma| methemoglobin| TNCY| hbg2

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