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  3. GSTA1

GSTA1 (Glutathione S-transferase alpha 1)

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Summary of GSTA1

The gene codes for a protein, glutathione S-transferase alpha 1. It aids with detoxification by conjugation of glutathione to a wide number of drugs and toxins [R].

It's better to have this gene increased most of the time.
0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Glutathione S-transferase A1

Short name:

GTH1

Alternative name(s):

GST HA subunit 1
GST class-alpha member 1
GST-epsilon
GSTA1-1

GSTA1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS3957357 (GSTA1) ??

Top Gene-Substance Interactions

GSTA1 Interacts with These Diseases

Disease Score

Substances That Increase GSTA1

Substances Interaction Organism Category

Substances That Decrease GSTA1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • AP-1
  • c-Jun
  • Sp1
  • c-Fos
  • CAR

Tissue specificity:

Liver.

Gene Pathways:

  • Metabolism
  • Glutathione metabolism
  • Metabolism of xenobiotics by cytochrome P450
  • Drug metabolism - cytochrome P450

Molecular Function:

  • Glutathione Peroxidase Activity
  • Glutathione Transferase Activity

Biological Processes:

  • Epithelial Cell Differentiation
  • Glutathione Derivative Biosynthetic Process
  • Glutathione Metabolic Process
  • Linoleic Acid Metabolic Process
  • Metabolic Process

Drug Bank:

  • Azathioprine
  • Busulfan
  • Glutathione
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

glutathione S-alkyltransferase A1| glutathione S-aryltransferase A1| glutathione S-transferase 2| glutathione S-transferase A1| glutathione S-transferase A3 subunit| glutathione S-transferase A5| glutathione S-transferase, alpha 1 (Ya)| glutathione S-transferase alpha-3| glutathione S-transferase alpha M14| Glutathione-S-transferase alpha type (Ya)| glutathione S-transferase Ha subunit 1| glutathione S-transferase Ya| glutathione S-transferase Ya1| glutathione S-transferase Yc1 subunit| gst2| Gst2-1| GST 2-2| GSTA1-1| Gsta3| GST A3-3| Gsta5| GST AA| GST class-alpha| GST class-alpha member 1| GST-epsilon| GST HA subunit 1| GST Yc1| gth1| OTTMUSG00000031890| S-(hydroxyalkyl)glutathione lyase A1| testicular tissue protein Li 80| Yc1| gsta1

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