The Function of GFRA1
Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
GDNF family receptor alpha-1Alternative name(s):
GDNF receptor alpha-1GDNFR-alpha-1
GFR-alpha-1
RET ligand 1
TGF-beta-related neurotrophic factor receptor 1
- RS12413355 (GFRA1) ??
- RS140018268 (GFRA1) ??
- RS146173241 (GFRA1) ??
- RS2302105 (GFRA1) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
GFRA1 Interacts with These Diseases
| Disease | Score |
Substances That Increase GFRA1
| Substances | Interaction | Organism | Category |
Substances That Decrease GFRA1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Molecular Function:
- Glial Cell-Derived Neurotrophic Factor Receptor Activity
- Ras Guanyl-Nucleotide Exchange Factor Activity
- Receptor Binding