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  3. GFRA1

GFRA1 (GDNF family receptor alpha 1)

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The Function of GFRA1

Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

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Protein names

Recommended name:

GDNF family receptor alpha-1

Alternative name(s):

GDNF receptor alpha-1
GDNFR-alpha-1
GFR-alpha-1
RET ligand 1
TGF-beta-related neurotrophic factor receptor 1

GFRA1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS12413355 (GFRA1) ??
  2. RS140018268 (GFRA1) ??
  3. RS146173241 (GFRA1) ??
  4. RS2302105 (GFRA1) ??

Top Gene-Substance Interactions

GFRA1 Interacts with These Diseases

Disease Score

Substances That Increase GFRA1

Substances Interaction Organism Category

Substances That Decrease GFRA1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Pax-2

Molecular Function:

  • Glial Cell-Derived Neurotrophic Factor Receptor Activity
  • Ras Guanyl-Nucleotide Exchange Factor Activity
  • Receptor Binding

Biological Processes:

  • Cell Surface Receptor Signaling Pathway
  • Mapk Cascade
  • Nervous System Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_06810| Anapl_11523| AS27_02788| AS28_09757| CB1_000678014| D623_10027908| GDNF family receptor alpha-1| GDNF family receptor alpha-1 isoform a preproprotein| GDNF family receptor alpha-1 isoform b preproprotein| GDNFR| gdnfra| GDNFR-alpha| GDNFRALPHA| GDNFR-alpha-1| GDNF receptor alpha| GDNF receptor alpha-1| gfr-alpha-1| GFR alpha-1| glial cell line derived neurotrophic factor family receptor alpha 1| Glial cell line-derived neurotrophic factor receptor alpha| GPI-linked anchor protein| H920_09616| M91_18499| M959_05886| N300_04599| N301_07064| N302_14899| N303_05168| N305_10808| N306_13984| N309_15282| N324_04513| N326_13539| N327_02221| N329_00519| N330_07494| N334_13580| PAL_GLEAN10014159| PANDA_005899| PI-linked cell-surface accessory protein| ret1l| RETL1| RET ligand 1| TGF-beta-related neurotrophic factor receptor 1| TREES_T100020259| trnr1| UY3_03740| Y1Q_013573| Y956_01379| gfra1

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