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  3. FDFT1

FDFT1 (Farnesyl-diphosphate farnesyltransferase 1)

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Summary of FDFT1

This gene encodes a protein that plays a role in cholesterol biosynthesis (R).

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Squalene synthase

Short name:

SS

Alternative name(s):

SQS
FPP:FPP farnesyltransferase
Farnesyl-diphosphate farnesyltransferase

FDFT1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1296028 (FDFT1) ??
  2. RS2645424 (FDFT1) ??
  3. RS2645430 (FDFT1) ??

Top Gene-Substance Interactions

FDFT1 Interacts with These Diseases

Disease Score

Substances That Increase FDFT1

Substances Interaction Organism Category

Substances That Decrease FDFT1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • ARP-1
  • Sox9
  • Msx-1
  • USF1
  • USF-1

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Steroid biosynthesis

Molecular Function:

  • Farnesyl-Diphosphate Farnesyltransferase Activity
  • Oxidoreductase Activity
  • Squalene Synthase Activity

Biological Processes:

  • Cholesterol Biosynthetic Process
  • Ergosterol Biosynthetic Process
  • Farnesyl Diphosphate Metabolic Process
  • Isoprenoid Biosynthetic Process
  • Steroid Biosynthetic Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| DGPT| AS27_12619| AS28_01617| EGK_18680| ERG9| farnesyl diphosphate farnesyltransferase| farnesyl-diphosphate farnesyltransferase| farnesyl diphosphate farnesyl transferase 1| fdft| FPP:FPP farnesyltransferase| H920_00447| M91_07539| M959_00807| N300_10974| N301_08997| N302_05113| N303_12296| N305_10462| N306_06830| N307_13670| N308_08617| N309_11865| N310_06038| N311_10441| N312_01358| N321_13414| N324_06030| N325_09569| N326_03458| N327_03060| N328_04493| N330_07111| N331_01123| N332_06326| N333_02903| N335_03150| N336_02471| N339_08249| N340_10108| N341_01056| PAL_GLEAN10016647| PANDA_012895| presqualene-di-diphosphate synthase| SQS| Squalene synthase| squalene synthetase| squalene synthetase-like protein| SS| TREES_T100016345| Y956_03763| Z169_07815| fdft1

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