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  3. CD226

CD226 (CD226 molecule)

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The Function of CD226

Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.

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Protein names

Recommended name:

CD226 antigen

Short name:

DNAM-1

Alternative name(s):

DNAX accessory molecule 1
CD antigen CD226

CD226 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS12969657 (CD226) ??
  2. RS17207042 (CD226) ??
  3. RS2469434 (CD226) ??
  4. RS727088 (CD226) ??
  5. RS763361 (CD226) ??

Top Gene-Substance Interactions

Substances That Increase CD226

Substances Interaction Organism Category

Substances That Decrease CD226

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • AP-1
  • c-Jun
  • Sp1

Tissue specificity:

Expressed by peripheral blood T-lymphocytes.

Gene Pathways:

  • Immune System
  • Cell adhesion molecules (CAMs)

Molecular Function:

  • Cell Adhesion Molecule Binding
  • Integrin Binding
  • Protein Homodimerization Activity
  • Protein Kinase Binding
  • Receptor Activity

Biological Processes:

  • Cell Adhesion
  • Cell Recognition
  • Cytokine Production
  • Heterophilic Cell-Cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
  • Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
  • Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
  • Positive Regulation Of Immunoglobulin Mediated Immune Response
  • Positive Regulation Of Interferon-Gamma Production
  • Positive Regulation Of Mast Cell Activation
  • Positive Regulation Of Natural Killer Cell Cytokine Production
  • Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
  • Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
  • Regulation Of Immune Response
  • Signal Transduction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| adhesion glycoprotein| AS27_10646| AS28_02539| CB1_001792005| CD226 antigen| CD226 antigen-like protein| DNAM1| DNAM-1| DNAX accessory molecule-1| GW7_16007| H920_00157| MDA_GLEAN10025356| N301_13968| N308_11267| N309_13235| N327_07074| N334_03655| N336_00878| PAL_GLEAN10017155| PANDA_004002| platelet and T cell activation antigen 1| PTA1| T lineage-specific activation antigen 1 antigen| TLiSA1| UY3_07187| Y956_00804| Z169_01412| cd226

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