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  3. BDKRB1

BDKRB1 (Bradykinin receptor B1)

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The Function of BDKRB1

This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

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Protein names

Recommended name:

B1 bradykinin receptor

Short name:

B1R

Alternative name(s):

BK-1 receptor

BDKRB1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS12050217 (BDKRB1) ??

Top Gene-Substance Interactions

BDKRB1 Interacts with These Diseases

Disease Score

Substances That Increase BDKRB1

Substances Interaction Organism Category

Substances That Decrease BDKRB1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • p53
  • Nkx2-5
  • p300

Gene Pathways:

  • Regulation of actin cytoskeleton
  • Signal Transduction
  • Neuroactive ligand-receptor interaction
  • Calcium signaling pathway
  • Complement and coagulation cascades

Molecular Function:

  • Bradykinin Receptor Activity
  • Peptide Binding

Biological Processes:

  • Inflammatory Response
  • Negative Regulation Of Blood Pressure
  • Negative Regulation Of Cell Growth
  • Negative Regulation Of Protein Phosphorylation
  • Positive Regulation Of Cytosolic Calcium Ion Concentration
  • Positive Regulation Of Leukocyte Migration
  • Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
  • Protein Kinase C-Activating G-Protein Coupled Receptor Signaling Pathway
  • Response To Lipopolysaccharide
  • Response To Mechanical Stimulus
  • Sensory Perception Of Pain
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| G-protein coupled receptor| B1BKR| B1 bradykinin receptor| b1 bradykinin receptor-like protein| B1 like bradykinin receptor| B1R| B2 bradykinin receptor| Bdkrb| bdkrb2| BK-1 receptor| BKB1R| BKR| BKR1| BRADYB1| bradykinin B1 receptor| bradykinin receptor 1| bradykinin receptor B2| bradykinin receptor, beta 1| CB1_000726063| GW7_16173| H920_17249| I79_010028| KB1| kinin B1| kinin B1 receptor| M91_16419| MDA_GLEAN10005394| PANDA_020542| bdkrb1

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