SelfDecode uses the only scientifically validated genetic prediction technology for consumers. Read more

Beyond DNA Tests: 30x Whole Genome Sequencing for Health Intelligence

You Are Missing Critical Genetic Information Right Now. Most DNA tests examine less than 0.1% of your genome. That leaves blind spots where serious medical risk can hide. Whole Genome Sequencing changes that.

SelfDecode’s 30x Whole Genome Sequencing analyzes 100% of your genetic code. Over 3 billion base pairs read directly, not inferred. This is the highest-resolution genetic testing for consumers available. No guessing. No gaps.

This is not a report. This is the data that powers every meaningful genetic insight you will ever receive. If a dangerous variant exists in your genome, this is how it gets found with near 100% accuracy.

We will never share your data

We follow HIPAA and GDPR policies

We have World-Class Encryption & Security

People Love Us

Rated 4.7/5 from 750+ reviews

People Trust Us

200,000+ users, 2,000+ doctors & 100+ businesses

See What Partial DNA Tests Can Never Show

30x Whole Genome Sequencing accurately captures the full genetic picture, not an estimate. We sequence everything once. Then we turn it into insights you can actually use.

Complete Variant Detection

Most DNA tests use genotyping, which analyzes only about 0.1% of your genetic code. By itself that snapshot is limited, but with advanced genetic imputation, like we use, those results expand far beyond the chip, unlocking ~200M of additional variants and much deeper insights while remaining an accessible way to explore your DNA.

Whole Genome Sequencing reads 100% of your DNA or 3 Billion variants, giving you the most complete and clinically actionable view of your genetics. Instead of sampling small sections, it captures your entire genome — helping you spot potential risks earlier, make proactive health decisions.

Medical-Grade Resolution

WGS reads coding and non-coding regions, structural variants, insertions, deletions, and complex mutations that lower-resolution tests miss entirely.

One Genome. Unlimited Insight.

Your sequenced genome can be reanalyzed as science advances. New discoveries do not require a new sample. Your data is already complete.

Why Whole Genome Sequencing Matters

Your health risks are not limited to the small fraction of DNA most tests analyze.

Genotyping looks at only a small part of your genome, so it can miss important genetic changes. Imagine reading a random chapter from a book. You might understand the general story, but you won’t see the exact details or know what the missing pages say. Whole Genome Sequencing (WGS) reads the entire book, giving you a clearer and more complete picture of your DNA instead of relying on guesses from partial information.

No report can recover what was never sequenced. Many rare conditions, medication responses, and inherited health risks are found in parts of your DNA that genotyping doesn’t fully examine. WGS gives you access to these variants and we help you understand what they mean.

Powered by SelfDecode Decody MCP, you gain an elite AI health consultant designed to guide smarter decisions — and redefine what’s possible for your health.

Stop Relying on Genetic Guesswork

Imputation is estimation. Sequencing is measurement.

Detect Risk Earlier and More Accurately

Rare variants with large medical impact are often missed by partial testing and caught by WGS.Rare variants with large medical impact are often missed by partial testing and caught by WGS.

Build a Future-Proof Genetic Foundation

WGS is the backbone for advanced reports including disease predisposition, pharmacogenomics, longevity, and precision prevention.

People love us

Our customers say

Excellent

4.7 out of 5 based on 700+ reviews

The Most Advanced 30x Whole Genome Sequencing Platform in Consumer Genetics

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ACMG SF v3.3 Clinical Predisposition Report

Not just insights — clinically actionable genetics. Powered by full 30x Whole Genome Sequencing and aligned with ACMG medical guidelines, this report screens for serious inherited risks most DNA tests never see. We translate complex clinical genetics into clear, prioritized insights so you can act early, not react later.

See Sample | Read More

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Advanced Pharmacogenomics (PGx)
— The Most Complete Drug Response Report on the Market

Built from your full 30x Whole Genome Sequencing, our PGx analysis covers 800+ medications with clearly ranked levels of scientific evidence. Instead of generic gene panels, we deliver deep variant analysis and physician-ready insights that help reduce trial-and-error prescribing. This is pharmacogenomics at a level typically reserved for advanced clinical settings — redesigned for real people.

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Ultimate Rare Variant Screening
— The Deepest Whole-Genome Analysis Available Today

This is where full-genome sequencing truly stands apart. We analyze thousands of rare conditions across your entire DNA to uncover hidden risks, carrier status, and high-impact variants — then turn them into personalized monitoring plans and actionable guidance. Rather than overwhelming you with raw genetics, we deliver a deeply personalized health intelligence layer built to evolve as new discoveries emerge.

This is the most complete form of personal genetic data ever available.

A simple, painless test that keeps unlocking new insights

Getting your genome sequenced is as easy as brushing your teeth. No blood draw, no clinic visit, no complicated logistics.

Your sample is processed with 30x clinical‑grade whole genome sequencing in our partner labs. Once your genome is sequenced, you never need to retest: every future SelfDecode report, from disease risk and ACMG findings to pharmacogenomics and longevity, is powered by the same complete dataset.

Step 1

We mail your SelfDecode DNA kit to your door.

Step 2

You gently swab the inside of your cheek for 1–2 minutes.

Step 3

You drop the prepaid package in the mail—and you’re done.

Not All 30X Sequencing Is the Same

Many companies advertise “30X Whole Genome Sequencing.”

Very few deliver true 30X coverage.

What “30X” Actually Means

30X refers to how many times, on average, each position in your genome is read. But averages can hide massive gaps.

Some tests sequence shallowly, then use statistical smoothing to fill in missing data, and claim 30X. Others reach 30X only in easy regions while medically important regions receive far fewer reads. This means the headline number may look strong, but the data is still not accurate.

SelfDecode covers your genome end to end — no gaps, no guesswork. You get real whole-genome data, not estimates filled in by algorithms. Your DNA doesn’t change, so you can use your results for life without chasing “upgrades” later.

What True 30X Coverage Delivers

True 30X means your genome is sequenced deeply and evenly, with enough real reads to confidently detect rare and high-impact variants.

SelfDecode’s Whole Genome Sequencing is designed for actual coverage, not marketing math.

High depth across clinically relevant regions

Reduced false negatives from low-read areas

Reliable detection of rare and structural variants

Data suitable for medical-grade downstream analysis

See Everything SelfDecode Has to Offer

Discover our full suite of health reports and features in one comprehensive guide.
Our Reports & Features Summary shows all the DNA results, tools, and insights you can get with SelfDecode.

One Test. The Highest Possible Ceiling.

You can take a cheaper test that gives partial answers. Or you can sequence your genome once and never hit a data wall again.

Whole Genome Sequencing is not an upgrade. It is the correct starting point.

HSA/FSA Eligible

US Based Lab & Shipping

30x Whole Genome Advanced Package

SelfDecode DNA Kit Included

ACMG SF v3.3-Based Predisposition Report
Advanced Pharmacogenomics (PGx) Report
Ultimate Rare Variant Screening
High-Coverage 30× Whole Genome Sequencing
SelfDecode Painless At-Home DNA Collection Kit
Full Lifetime Access to Your Genetic Information
Permanent Privacy-First Data Protection

$1499

SelfDecode user or outside the US?

Order Here

HSA & FSA Eligible

ACMG SF v3.3 Clinical Predisposition Report

SelfDecode DNA Kit Included

ACMG SF v3.3-Based Predisposition Report
High-Coverage 30× Whole Genome Sequencing
SelfDecode Painless At-Home DNA Collection Kit
Full Lifetime Access to Your Genetic Information
Permanent Privacy-First Data Protection

$749

HSA & FSA Eligible

SelfDecode user or outside the US?

Order Here

Advanced Pharmacogenomics (PGx) Report

SelfDecode DNA Kit Included

Advanced Pharmacogenomics (PGx) Report
High-Coverage 30× Whole Genome Sequencing
SelfDecode Painless At-Home DNA Collection Kit
Full Lifetime Access to Your Genetic Information
Permanent Privacy-First Data Protection

$749

HSA & FSA Eligible

SelfDecode user or outside the US?

Order Here

Ultimate Rare Variant Screening

SelfDecode DNA Kit Included

Ultimate Rare Variant Screening
High-Coverage 30× Whole Genome Sequencing
SelfDecode Painless At-Home DNA Collection Kit
Full Lifetime Access to Your Genetic Information
Permanent Privacy-First Data Protection

$999

HSA & FSA Eligible

SelfDecode user or outside the US?

Order Here

We will never share your data

We follow HIPAA and GDPR policies

We have World-Class Encryption & Security

People Love Us

Rated 4.7/5 from 750+ reviews

People Trust Us

200,000+ users, 2,000+ doctors & 100+ businesses

SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode strongly encourages those who use our service to consult and work with an experienced healthcare provider as our services are not to replace the relationship with a licensed doctor or regular medical screenings.

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Beyond DNA Tests: 30x Whole Genome Sequencing for Health Intelligence

See What Partial DNA Tests Can Never Show

Why Whole Genome Sequencing Matters

People love us

The Most Advanced 30x Whole Genome Sequencing Platform in Consumer Genetics

A simple, painless test that keeps unlocking new insights

Not All 30X Sequencing Is the Same

What True 30X Coverage Delivers

See Everything SelfDecode Has to Offer

One Test. The Highest Possible Ceiling.

30x Whole Genome Advanced Package

ACMG SF v3.3 Clinical Predisposition Report

Advanced Pharmacogenomics (PGx) Report

Ultimate Rare Variant Screening

Policies

About

Navigation

Health reports