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rs314263

Chromosome : 6 , Position: 104944870
Most conditions are affected by anywhere from hundreds to millions of genetic variants (SNPs). A single SNP usually has a minor contribution to a person’s overall genetic risk for a certain condition. That is why you shouldn't consider or act on a SNP in isolation. Instead, we use SNPs to determine polygenic risk scores (PRSs), which are the basis of most health reports.
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Reference AlleleC
Alternative Alleles:  T

Traits

Trait Variant Impact PMID Author (year)
Height T
Nat Genet Wood AR (2014)
Body fat distribution (trunk fat ratio) [females] T
Nat Commun Rask-Andersen M (2019)
Body fat distribution (trunk fat ratio) T
Nat Commun Rask-Andersen M (2019)
Body fat distribution (leg fat ratio) [females] T
Nat Commun Rask-Andersen M (2019)
Body fat distribution (trunk fat ratio) [males] T
Nat Commun Rask-Andersen M (2019)
Body fat distribution (leg fat ratio) T
Nat Commun Rask-Andersen M (2019)
Body fat distribution (leg fat ratio) [males] T
Nat Commun Rask-Andersen M (2019)

Summary

menarche about six weeks earlier
  • 1.2x accelerated breast development and a faster rate of increase in height and weight.
  • a reduction in adult height of about 0.15 inches.
  • Male
    • 1.26 greater odds of advanced voice breaking at age 15
    • 1.19 times greater odds of advanced pubic hair at age 13
    • faster rate of growth at age 10 and about a tenth of an inch less in adult height.
  • [PMID 20546612] The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.

    More Information

    menarche about six weeks earlier
  • 1.2x accelerated breast development and a faster rate of increase in height and weight.
  • a reduction in adult height of about 0.15 inches.
  • Male
    • 1.26 greater odds of advanced voice breaking at age 15
    • 1.19 times greater odds of advanced pubic hair at age 13
    • faster rate of growth at age 10 and about a tenth of an inch less in adult height.
  • [PMID 20546612] The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.

    Population Alleles Frequency

    ethhicity frequency
    African/African-American 0.6888
    Latino/Admixed American 0.7547
    Ashkenazi Jewish 0.6897
    East Asian 0.6714
    European 0.6728
    Other (population not assigned) 0.6888

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    Health reports

    High Blood Sugar
    Anxiety
    Gluten Sensitivity
    Gut Inflammation
    Blood Pressure
    IBS
    Mood
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    Myopia
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    Testosterone – Males
    Yeast infection (Candida)
    Endometriosis
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    Uterine fibroids
    Length of menstrual cycle
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    Cluster headaches
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    Selenium
    Low back injury
    Dyslexia
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    High PTH
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    Coenzyme Q10 (CoQ10)
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    Salicylate Sensitivity
    Facial Wrinkles
    Age Spots
    Ligament Rupture (ACL Injury)
    Tendon Injury (Tendinopathy)
    Omega 6
    Omega 6:Omega 3 Ratio
    Arachidonic Acid
    Oleic Acid
    Alpha-Linolenic Acid
    EPA
    GLA
    Linoleic Acid
    DHA
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    Sodium
    MCHC
    Alkaline Phosphatase
    Monocytes
    Ghrelin
    IL10 (Th2)
    IL-6 (Th2 and Th17)
    Iodine
    Chili Pepper sensitivity
    COMT
    DRD2 (Dopamine)
    Lectin Sensitivity
    Thiamine
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    Chronic Lyme
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    Glyphosate sensitivity
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    Pregnenolone
    Luteinizing Hormone (LH)
    Growth Hormone
    IgA
    Molybdenum
    Sensitivity to Dairy (IgG Casein)
    Telomere Length
    Serotonin (5HIAA)
    Non-Celiac Gluten Sensitivity (IgG Gliadin)
    Manganese
    Klotho
    Mold Sensitivity (Airborne)
    Amylase
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    Low Sperm Count
    Tryptophan
    Methionine
    Glutamate
    Proline
    Blood Calcium
    Hypertriglyceridemia
    HDL Cholesterol
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    Bilirubin (total)
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    Red blood cell count
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    eGFR
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    Neuroticism
    Sleep Quality
    Lactose Intolerance
    Saturated fat
    Optimal diet
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    Achilles tendon injury
    Deep sleep
    Fat
    Response to Stress
    Leadership
    Ankle injury
    Creativity
    Hoarding
    Protein
    Optimal Exercise
    Knee Injury
    Rotator cuff injury
    Extraversion
    Risk-Taking
    Happiness
    Daytime Sleepiness
    Morningness
    Time spent watching TV
    Disliking cilantro
    Alcohol Sensitivity
    Response to Caffeine
    Snacking
    Weight Regain
    Sleep movement
    Wearing glasses or contacts
    Educational Attainment
    Bitter Taste Sensitivity
    Agreeableness
    Aggression
    Conscientiousness
    Openness to experience
    Physical activity
    Caffeine-Related Anxiety
    Naps