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NFKBIL1
SNP Table
| variant | genotype | frequency | risk allele |
|---|---|---|---|
| rs74367810 | |||
| rs113695302 | |||
| rs115225594 | |||
| rs72847222 | |||
| rs2255798 | |||
| rs1309487857 | |||
| rs1435233936 | |||
| rs149963082 | |||
| rs184070214 | |||
| rs201523402 | |||
| rs2516486 | |||
| rs3130062 | |||
| rs372327185 | |||
| rs533781175 | |||
| rs72847218 | |||
| rs9380261 | |||
| rs9469021 | |||
| rs77192564 | |||
| rs114060326 | |||
| rs11796 |
Find on This Page
Summary
The gene codes for a protein, NFKB inhibitor like 1. Function has not yet been determined [R].
Protein names
Found in These Blog Articles
GHR Function
Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli.
More Information
From NCBI Gene: Rheumatoid arthritisFrom UniProt: Rheumatoid arthritis (RA): An inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. [MIM:180300]
From NCBI Gene: This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009] From UniProt: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli.
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