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Dirty Genes:
Decode What’s Holding You Back

Inspired by the work of Dr. Ben Lynch, but created independently by SelfDecode

Discover how your genes may be impacting your health. While this report draws inspiration from Dr. Lynch’s groundbreaking ideas in functional medicine, it is uniquely developed by SelfDecode to help you uncover your personal genetic variations and get tailored insights to support your wellness journey.

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What Are
"Dirty Genes"?

The term “dirty genes,” coined by Dr. Ben Lynch, refers to genetic variations that may not be functioning at their best, causing your detox systems to stall, mood to fluctuate, energy to crash, and hormones to misfire.

These gene variants don’t mean you’re broken. But they can slow down vital pathways like methylation, detoxification, and neurotransmitter balance, especially when pushed by stress, toxins, or the wrong supplements.

The good news? You can clean your genes.

Clean Genes Start With Knowledge

SelfDecode shows you how your genes behave and more importantly, what you can do about it.
Here are a few genes that could be holding you back:

🧠
MTHFR

Involved in converting folate into its active form for detox, mood, and DNA repair. A sluggish MTHFR can result in brain fog, fatigue, irritability, and poor stress tolerance.

COMT

Helps break down dopamine, adrenaline, and estrogen. Too fast or too slow COMT activity? You could feel overly anxious… or unmotivated and flat.

🛡️
GSTT1 & GSTM1

Part of your glutathione system. If these genes are underperforming, your body may struggle to neutralize toxins, increasing oxidative stress.

🧪
CYP450 Family

These enzymes break down medications and chemicals. Variants here affect how you metabolize drugs and toxins, making you more sensitive or resistant.

🌿
MAO-A

Breaks down mood-related neurotransmitters like serotonin and norepinephrine. Variants can influence emotional reactivity and mood balance.

🧬
PEMT

Often overlooked, but critical. It supports liver function and brain clarity by helping make phosphatidylcholine. Dirty PEMT? Think fatigue, sluggish detox, poor memory.

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Your Genes Aren’t Your Destiny.
But They’re a Clue.

You might be doing “everything right”. Eating clean, taking your supplements, exercising and still feeling off. That’s where understanding your “dirty genes” changes everything.

Your genes don’t operate in a vacuum. They’re influenced by:

Diet
Sleep
Stress
Toxins
Lifestyle
Supplements

You can support your underperforming genes with the right tools if you know where to look.

See a sample Dirty Genes report

View our sample report, just one of over 1,250 personalized insights waiting for you. With SelfDecode, you get more than a static PDF; you unlock an AI-powered health coach, tools to analyze your labs and lifestyle, and access to thousands of tailored reports packed with actionable recommendations.

Get the Full Picture with SelfDecode

SelfDecode goes beyond MTHFR and COMT. You’ll get insights into 1,250+ health topics, covering your detox system, hormones, neurotransmitters, and more.

Included with your membership:

Your Genes Don’t Define You. But They Can Guide You.

Ready to take control of your health? Start optimizing your genes today with SelfDecode and unlock personalized insights tailored to your unique genetic profile.

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We will never share your data

We follow HIPAA and GDPR policies

We have World-Class Encryption & Security

People Love Us

Rated 4.7/5 from 750+ reviews

People Trust Us

200,000+ users, 2,000+ doctors & 100+ businesses

About Dr. Ben Lynch

Dr. Ben Lynch is a best-selling author, founder of Seeking Health, and a globally recognized expert in nutrigenomics and functional medicine. His groundbreaking book Dirty Genes has changed the way people think about genetics, focusing on how lifestyle and environment can clean up suboptimal gene expression.

Learn more about Dr. Lynch at www.drbenlynch.com or check out his best-selling book, Dirty Genes.

SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode strongly encourages those who use our service to consult and work with an experienced healthcare provider as our services are not to replace the relationship with a licensed doctor or regular medical screenings.

SelfDecode © 2025. All rights reserved.

Health reports

High Blood Sugar
Anxiety
Gluten Sensitivity
Gut Inflammation
Blood Pressure
IBS
Mood
Insomnia
PTSD
Mood Swings
Overweight
Memory Performance
Sexual Dysfunction
PCOS
Psoriasis
Joint Pain
Attention/ADHD
Chronic Fatigue / Tiredness
Allergies
Asthma
Acne
Tinnitus
Eczema
Food Allergy
Vitamin B6
Vitamin E
Restless Leg Syndrome
Grinding Teeth
Vitamin A
Magnesium
Zinc
Heart Health
Migraines
(High) Cholesterol
Headache
Chronic Pain
Back pain
Shoulder & Neck Pain
Stress
Inflammation
Omega-3 needs
Salt Sensitivity
Endurance
Power performance
Strength
Exercise recovery
Brain Fog
Female Fertility
Longevity
Addiction
Erectile Dysfunction
Male Infertility
MTHFR
Joint Inflammation
GERD
Ulcers
Sleep Apnea
Periodontitis
Varicose Veins
H. pylori
Liver Health
Canker Sores
Gallstones
Kidney Health
Gout
Hair Loss (Male-Pattern Baldness)
Riboflavin
Urticaria
Rosacea
Carpal Tunnel Syndrome
Sinus Congestion
Cavities
Artery Hardening
Vertigo
Vitiligo
Myopia
Indigestion
Excessive Sweating
Testosterone – Males
Yeast infection (Candida)
Endometriosis
Tobacco addiction
Alcohol addiction
Uterine fibroids
Length of menstrual cycle
UTI
OCD
Kidney Stones
Vitamin B12
Vitamin C
Vitamin D
Folate
Iron
Eating Disorders
Bone Health
Hypothyroidism
Hyperthyroidism
Sugar Cravings
Hearing/difficulty problem /Hearing loss
Painful Periods
Palpitations
Hemorrhoids
Hypotension
Bladder Control
Constipation
Appendicitis
Low Blood Sugar
Irregular Periods
Metabolic rate
Visceral fat
Lung Health
Anemia
Calcium
Cognition
Cognitive Decline
Seasonal Low Mood
Vitamin K
Phosphate
HRV
Cluster headaches
Knee Pain
Hip Pain
Selenium
Low back injury
Dyslexia
Cannabis addiction
Histamine Intolerance
Carnitine
Pesticide Sensitivity
Organophosphate Sensitivity
Cadmium
Lead
Melatonin
FSH
T4
T3
High PTH
Potassium
Coenzyme Q10 (CoQ10)
Chromium
Oxalate Sensitivity
Salicylate Sensitivity
Facial Wrinkles
Age Spots
Ligament Rupture (ACL Injury)
Tendon Injury (Tendinopathy)
Omega 6
Omega 6:Omega 3 Ratio
Arachidonic Acid
Oleic Acid
Alpha-Linolenic Acid
EPA
GLA
Linoleic Acid
DHA
Insulin Resistance
Sperm Motility
Homocysteine
C difficile
Pneumonia
EBV Infection
Gastrointestinal Infection
Chronic Bronchitis
Copper
Skin Elasticity
Skin Hydration
Egg allergy
ApoB
GGT
TIBC
Bioavailable Testosterone (Male)
MPV
Chloride
Free T4
Processing Speed
Short-term memory
TMAO
Air pollution sensitivity
Heart Rate
VO2 Max
Flu
Hair graying
Caffeine-Related Sleep Problems
Groin Hernia
Stretch marks
Droopy Eyelids
Strep infection
Dry eyes
Carbohydrate Consumption
Peanut allergy
Heart rate recovery
Muscle recovery
Jaw Disorders
HPV Infection
Acute Bronchitis
Chlamydia
Genital Herpes
Pancreas inflammation
Executive Function
Pyroglutamic acid
Raynaud’s
Liver Scarring
Dandruff
Bioavailable Testosterone (Female)
Shrimp allergy
Haptoglobin
Milk allergy
Beta-Alanine
Taurine
LDL Particle Size
Diarrhea
Snoring
Uric acid
Phenylalanine
Leucine
Glutamine
Valine
Glycine
Alanine
Lysine
Arginine
Histidine
Tyrosine
Cortisol
DHEAS
Insulin
Prolactin
TSH
Lactate
Ketone Bodies
IL-17A (Th17 Dominance)
Creatine Kinase
Neutrophils
Basophils
Eosinophils
Ferritin
ALT
AST
MCV
Hematocrit
RDW
SHBG
Total Protein
Albumin
MCH
Sodium
MCHC
Alkaline Phosphatase
Monocytes
Ghrelin
IL10 (Th2)
IL-6 (Th2 and Th17)
Iodine
Chili Pepper sensitivity
COMT
DRD2 (Dopamine)
Lectin Sensitivity
Thiamine
Biotin
Mold Sensitivity (Foodborne)
Chronic Lyme
BDNF
Glyphosate sensitivity
BPA Sensitivity
Pregnenolone
Luteinizing Hormone (LH)
Growth Hormone
IgA
Molybdenum
Sensitivity to Dairy (IgG Casein)
Telomere Length
Serotonin (5HIAA)
Non-Celiac Gluten Sensitivity (IgG Gliadin)
Manganese
Klotho
Mold Sensitivity (Airborne)
Amylase
Lipase
Low Sperm Count
Tryptophan
Methionine
Glutamate
Proline
Blood Calcium
Hypertriglyceridemia
HDL Cholesterol
HbA1c
Hemoglobin
Total Cholesterol
LDL Cholesterol
IGF1
Fasting Glucose
Bilirubin (total)
White blood cell count
Red blood cell count
Platelets
eGFR
Creatinine
Estradiol
Neuroticism
Sleep Quality
Lactose Intolerance
Saturated fat
Optimal diet
Unsaturated fat
Achilles tendon injury
Deep sleep
Fat
Response to Stress
Leadership
Ankle injury
Creativity
Hoarding
Protein
Optimal Exercise
Knee Injury
Rotator cuff injury
Extraversion
Risk-Taking
Happiness
Daytime Sleepiness
Morningness
Time spent watching TV
Disliking cilantro
Alcohol Sensitivity
Response to Caffeine
Snacking
Weight Regain
Sleep movement
Wearing glasses or contacts
Educational Attainment
Bitter Taste Sensitivity
Agreeableness
Aggression
Conscientiousness
Openness to experience
Physical activity
Caffeine-Related Anxiety
Naps