What does the ABCA6 (Cholesterol) gene do?

ABCA6 is a gene in the ABC transporter family, which helps cells move and manage substances across their membranes. In practical terms, ABCA6 appears to be involved in how cells handle fats and cholesterol—acting like part of a cellular transport and “recycling” system. It’s particularly active in the liver, where much of your cholesterol processing and packaging happens, suggesting it may help cells avoid accumulating excessive cholesterol and fatty molecules.

Why is the ABCA6 (Cholesterol) gene important?

ABCA6 matters because differences (genetic variants) in this gene may influence cholesterol-related markers that are closely tied to cardiovascular risk, including total cholesterol, LDL cholesterol, and ApoB. While ABCA6 is not as well-established as some other cholesterol genes, research has linked a rare variant (rs77542162-G) to higher cholesterol markers—and interestingly, to a potentially greater LDL reduction from fish oil supplements. Knowing your ABCA6 profile can help you and your healthcare team personalize prevention strategies for heart and blood vessel health.

What can I do based on my ABCA6 (Cholesterol) results?

Based on your ABCA6 (Cholesterol) results, you’ll receive 6 personalized recommendations across dietary, drug, and supplement categories. These are designed to help you act on your genetic insights—such as nutrition adjustments to better support LDL/ApoB management, supplement guidance (including whether fish oil may be a better fit for your genotype), and medication-related considerations to discuss with your clinician. Your report turns genetic signals into clear next steps tailored to you.

Can ABCA6 genetic variants affect LDL cholesterol and ApoB?

Yes. Research suggests certain ABCA6 genetic variants are associated with differences in cholesterol-related biomarkers, including LDL cholesterol and ApoB. ApoB reflects the number of atherogenic (“plaque-forming”) particles in the blood, so shifts in ApoB can be clinically meaningful for heart and blood vessel risk. The ABCA6 report focuses on how your variants may relate to these markers and provides personalized actions—dietary, supplement, and drug-related considerations—to help you respond more effectively than using one-size-fits-all advice.

Does ABCA6 genetic testing predict fish oil response for cholesterol?

ABCA6 genetic testing may offer clues about fish oil response for some people. A rare ABCA6 variant (rs77542162-G) has been linked not only to higher baseline cholesterol markers, but also to a greater LDL reduction with fish oil supplementation in certain studies. Your report interprets your ABCA6 genotype in the context of available evidence and translates it into supplement guidance—helping you understand whether fish oil is more likely to be beneficial for your LDL strategy, and what to discuss with a healthcare professional.

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ABCA6 (Cholesterol)

Rated 4.70 out of 5 based on 10 customer ratings

4.7 (11 reviews)

ABCA6 (Cholesterol)

Rated 4.70 out of 5 based on 10 customer ratings

4.7 (11 reviews)

The report provides up to 6 personalized recommendations based on your genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Trusted by 200,000+ users & 2,000+ doctors

Proven track record: 3+ million analyses delivered

Analyzes Key Genetic Variants

Up to 6 DNA-Based, Science-Backed Recommendations

ABCA6 (Cholesterol)

$59 $29

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Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your ABCA6 (Cholesterol) Variants: A DNA Gene Report

Have you ever wondered why your cholesterol numbers don’t respond the same way as someone else’s—even when you eat similarly? Curious whether your genes could influence LDL (“bad”) cholesterol, ApoB, or how well fish oil works for you? Your ABCA6 (Cholesterol) gene helps manage how cells handle fats and cholesterol, and understanding your ABCA6 genetic variants can add a personalized layer to protecting your heart and blood vessels.

Key Report Highlights

This ABCA6 (Cholesterol) Gene Report analyzes genetic variants linked to cholesterol-related traits and provides 6 personalized recommendations tailored to your DNA. ABCA6 is part of the ABC transporter family—proteins that help move substances across cell membranes—and it’s especially active in the liver, your body’s cholesterol processing hub. A compelling finding: certain ABCA6 variants have been associated with higher total cholesterol, LDL cholesterol, and ApoB, and may also influence how strongly LDL responds to fish oil supplementation.

Personalized, Actionable Recommendations

Your results translate into practical, genotype-based guidance, with dietary, drug, and supplement recommendations aligned to your ABCA6 (Cholesterol) profile. Depending on your genetic variants, your report may highlight targeted strategies to support healthier LDL and ApoB—such as adjusting the type of fats you prioritize in your diet—or provide supplement guidance, including whether fish oil may be more likely to lower LDL for you. You’ll also see medication-related considerations you can discuss with your clinician, designed to complement (not replace) professional care.

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: ABCA6 is a gene in the ABC transporter family, which helps cells move and manage substances across their membranes. In practical terms, ABCA6 appears to be involved in how cells handle fats and cholesterol—acting like part of a cellular transport and “recycling” system. It’s particularly active in the liver, where much of your cholesterol processing and packaging happens, suggesting it may help cells avoid accumulating excessive cholesterol and fatty molecules.
: ABCA6 matters because differences (genetic variants) in this gene may influence cholesterol-related markers that are closely tied to cardiovascular risk, including total cholesterol, LDL cholesterol, and ApoB. While ABCA6 is not as well-established as some other cholesterol genes, research has linked a rare variant (rs77542162-G) to higher cholesterol markers—and interestingly, to a potentially greater LDL reduction from fish oil supplements. Knowing your ABCA6 profile can help you and your healthcare team personalize prevention strategies for heart and blood vessel health.
: Based on your ABCA6 (Cholesterol) results, you’ll receive 6 personalized recommendations across dietary, drug, and supplement categories. These are designed to help you act on your genetic insights—such as nutrition adjustments to better support LDL/ApoB management, supplement guidance (including whether fish oil may be a better fit for your genotype), and medication-related considerations to discuss with your clinician. Your report turns genetic signals into clear next steps tailored to you.
: Yes. Research suggests certain ABCA6 genetic variants are associated with differences in cholesterol-related biomarkers, including LDL cholesterol and ApoB. ApoB reflects the number of atherogenic (“plaque-forming”) particles in the blood, so shifts in ApoB can be clinically meaningful for heart and blood vessel risk. The ABCA6 report focuses on how your variants may relate to these markers and provides personalized actions—dietary, supplement, and drug-related considerations—to help you respond more effectively than using one-size-fits-all advice.
: ABCA6 genetic testing may offer clues about fish oil response for some people. A rare ABCA6 variant (rs77542162-G) has been linked not only to higher baseline cholesterol markers, but also to a greater LDL reduction with fish oil supplementation in certain studies. Your report interprets your ABCA6 genotype in the context of available evidence and translates it into supplement guidance—helping you understand whether fish oil is more likely to be beneficial for your LDL strategy, and what to discuss with a healthcare professional.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.70 out of 5 based on 10 customer ratings

4.7 (11 reviews)

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Scarlett F.

Rated 5 out of 5
I am 29 and my cholesterol surprised me during a routine check. The ABCA6 (Cholesterol) report made the Heart and Blood Vessels section feel personal, not generic. It spelled out how limiting trans fats could matter more for my profile, and it gave specific, doable ideas to increase dietary oleic acid, like switching cooking oils and choosing certain nuts. I also liked that it listed olive polyphenols as an option and explained what to watch for. I took the summary to my clinician, and our conversation about ezetimibe felt way more productive.
Aurora D.

Rated 3 out of 5
Useful, but too medication focused. I wanted more on olive polyphenols dosing and food examples, not just ezetimibe and bempedoic acid mentions.
Daiki L.

Rated 5 out of 5
Usually when I want health info, I end up lost in endless blogs or confusing search results, but this cut right to what I wanted to know. It gave me actionable advice based on my actual genes which is so much more direct than most sources out there.
Neil U.

Rated 5 out of 5
I’ve purchased several DNA insights from this company and the cholesterol one stands out. I feel like I get actionable steps every time, but this was extra clear for heart health. Love knowing what to focus on personally!
Camille S.

Rated 5 out of 5
Le rapport ABCA6 m’a aidé à cibler mes graisses, plus d’acide oléique, moins de trans, et discussion utile sur l’ézétimibe avec mon médecin.

ABCA6 (Cholesterol)

Product features

Understanding Your ABCA6 (Cholesterol) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the ABCA6 (Cholesterol) gene do?

Why is the ABCA6 (Cholesterol) gene important?

What can I do based on my ABCA6 (Cholesterol) results?

Can ABCA6 genetic variants affect LDL cholesterol and ApoB?

Does ABCA6 genetic testing predict fish oil response for cholesterol?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers