What does the NAT1 (Detox) gene do?

The NAT1 (Detox) gene provides instructions for making an enzyme called N-acetyltransferase 1. This enzyme helps your body “tag” certain substances through a process called acetylation, which can make various drugs, environmental chemicals, and potential toxins easier to process and remove. NAT1 is active in detox-related tissues (including the liver) and works alongside NAT2 in handling multiple compounds that come from the environment and diet.

Why is the NAT1 (Detox) gene important?

NAT1 is important because common genetic variants can change NAT1 enzyme activity and shift you toward a slower, intermediate, or faster acetylation pattern. These differences may influence how strongly you’re affected by specific exposures. For instance, certain variants linked to slower acetylation have been associated with higher susceptibility to some cancer risks in particular contexts (such as smoking-related risk), while variants associated with higher activity may relate to increased colorectal cancer risk in people with high intake of cooked or well-done meats. Understanding your NAT1 variants helps put these exposure-related risks into a more personalized, actionable context.

What can I do based on my NAT1 (Detox) results?

Based on your NAT1 (Detox) results, you’ll receive 1 personalized recommendation focused on supplement guidance. This recommendation is tailored to your genotype and is designed to support detox-related pathways connected to NAT1 activity. Depending on your genetic pattern, your report may also highlight practical considerations to discuss with a clinician—such as being more mindful of certain exposures (e.g., smoking or frequent well-done meat intake) and supporting related nutritional pathways that intersect with NAT1 function.

How does the NAT1 (Detox) gene affect detoxification and cancer risk?

NAT1 influences detoxification through acetylation—an enzyme-driven step that can change how certain chemicals are processed in the body. Genetic variants in NAT1 can alter enzyme activity, which may modify how you respond to exposures like cigarette smoke byproducts or compounds formed during high-temperature cooking of meat. Research has linked specific NAT1 alleles to different risk patterns (for example, increased lung cancer risk in smokers for some slow-acetylator variants, and increased colorectal cancer risk in some higher-activity contexts with high cooked-meat intake). A DNA-based NAT1 report helps connect these findings to your personal genotype so you can focus on the exposures and supportive strategies most relevant to you.

What do NAT1 genetic variants (SNPs) tell you in a NAT1 DNA test?

A NAT1 DNA test evaluates specific SNPs that can influence NAT1 expression or enzyme activity, helping classify your acetylation-related tendencies. In this report, 4 NAT1 variants are analyzed to provide a clearer picture of how your NAT1 pathway may function and what that could mean for detox handling of certain compounds. Your results are then translated into a personalized, genotype-based takeaway—including 1 tailored supplement recommendation—so you can move from raw genetics to practical next steps.

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NAT1 (Detox)

Rated 4.90 out of 5 based on 10 customer ratings

4.9 (11 reviews)

NAT1 (Detox)

Rated 4.90 out of 5 based on 10 customer ratings

4.9 (11 reviews)

The report provides up to 1 personalized recommendations based on 4 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Trusted by 200,000+ users & 2,000+ doctors

Proven track record: 3+ million analyses delivered

Analyzes 4 Genetic Variants

Up to 1 DNA-Based, Science-Backed Recommendations

NAT1 (Detox)

$59 $29

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Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your NAT1 (Detox) Variants: A DNA Gene Report

Do you ever wonder why certain medications, smoke exposure, or even well-done meat seem to affect some people more than others? Have you been curious about how your body “processes” everyday chemicals and potential carcinogens? Your NAT1 (Detox) gene helps control how efficiently you acetylate (a key detox step) a wide range of compounds—so understanding your NAT1 genetic variants can offer clearer, more personal insight into detox capacity and cancer-related risk patterns.

Key Report Highlights

This NAT1 (Detox) Gene Report analyzes 4 clinically relevant genetic variants (SNPs) to help characterize your acetylation pattern and what it may mean for detox and cancer-related pathways. You’ll also receive 1 personalized recommendation tailored to your genotype, focused on targeted supplement guidance. NAT1 encodes an enzyme (N-acetyltransferase 1) that helps make certain toxins and drug-like compounds easier to eliminate—an important biological “processing step” that can influence how your body responds to exposures like cigarette smoke and cooked-meat byproducts.

Personalized, Actionable Recommendations

Your results translate your NAT1 (Detox) genotype into practical, personalized guidance—so you’re not left guessing what your DNA means. Based on your acetylation-related variants, the report provides 1 targeted supplement recommendation designed to support your detox pathways in a way that matches your genetics. For example, your guidance may include a supplement strategy that supports healthy acetylation and overall detox capacity, or a recommendation aligned with pathways connected to folate-related metabolism that may interact with NAT1 function.

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: The NAT1 (Detox) gene provides instructions for making an enzyme called N-acetyltransferase 1. This enzyme helps your body “tag” certain substances through a process called acetylation, which can make various drugs, environmental chemicals, and potential toxins easier to process and remove. NAT1 is active in detox-related tissues (including the liver) and works alongside NAT2 in handling multiple compounds that come from the environment and diet.
: NAT1 is important because common genetic variants can change NAT1 enzyme activity and shift you toward a slower, intermediate, or faster acetylation pattern. These differences may influence how strongly you’re affected by specific exposures. For instance, certain variants linked to slower acetylation have been associated with higher susceptibility to some cancer risks in particular contexts (such as smoking-related risk), while variants associated with higher activity may relate to increased colorectal cancer risk in people with high intake of cooked or well-done meats. Understanding your NAT1 variants helps put these exposure-related risks into a more personalized, actionable context.
: Based on your NAT1 (Detox) results, you’ll receive 1 personalized recommendation focused on supplement guidance. This recommendation is tailored to your genotype and is designed to support detox-related pathways connected to NAT1 activity. Depending on your genetic pattern, your report may also highlight practical considerations to discuss with a clinician—such as being more mindful of certain exposures (e.g., smoking or frequent well-done meat intake) and supporting related nutritional pathways that intersect with NAT1 function.
: NAT1 influences detoxification through acetylation—an enzyme-driven step that can change how certain chemicals are processed in the body. Genetic variants in NAT1 can alter enzyme activity, which may modify how you respond to exposures like cigarette smoke byproducts or compounds formed during high-temperature cooking of meat. Research has linked specific NAT1 alleles to different risk patterns (for example, increased lung cancer risk in smokers for some slow-acetylator variants, and increased colorectal cancer risk in some higher-activity contexts with high cooked-meat intake). A DNA-based NAT1 report helps connect these findings to your personal genotype so you can focus on the exposures and supportive strategies most relevant to you.
: A NAT1 DNA test evaluates specific SNPs that can influence NAT1 expression or enzyme activity, helping classify your acetylation-related tendencies. In this report, 4 NAT1 variants are analyzed to provide a clearer picture of how your NAT1 pathway may function and what that could mean for detox handling of certain compounds. Your results are then translated into a personalized, genotype-based takeaway—including 1 tailored supplement recommendation—so you can move from raw genetics to practical next steps.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.90 out of 5 based on 10 customer ratings

4.9 (11 reviews)

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Isla S.

Rated 5 out of 5
I never realized how much detox genetics could affect my energy levels. After making some of the suggested changes, I actually wake up feeling refreshed.
Courtney H.

Rated 5 out of 5
I’m in my early 40s and work around solvents and paints, so I grabbed the NAT1 (Detox) report to see if my genetics could explain why I feel wiped out after certain exposures. The report broke down NAT1 in plain language and helped me connect the dots between detox pathways and my symptoms. I started the suggested N-acetylcysteine (NAC), cleaned up my protein and veggie balance, and got more consistent with sleep. Within a month my “chemical hangover” feeling was noticeably lighter, and I recover faster after long shop days. It gave me a concrete plan instead of guesswork.
Laura S.

Rated 5 out of 5
Compré el informe NAT1 (Detox) porque en mi familia hay antecedentes de sensibilidad a químicos y yo me sentía “cargada” después de tomar alcohol o medicamentos comunes. El reporte explicó de forma clara qué significa mi variante en NAT1 para la fase de detox y por qué ciertos hábitos me podían estar pasando factura. Lo mejor fue que no se quedó en teoría: probé N-acetilcisteína (NAC) según la recomendación, mejoré hidratación y prioricé verduras crucíferas. En pocas semanas noté menos dolor de cabeza y una energía más estable tras días de trabajo intenso.
Hailey L.

Rated 5 out of 5
After reading, I started taking NAC daily and made sure to add more cruciferous veggies like broccoli. Honestly, I feel less sluggish and my skin actually improved too. It motivated me to take detox seriously for once!
Dan C.

Rated 5 out of 5
I’ve bought several of these health genetics things and the nat1 detox was just as clear and actionable as the others. Felt like this one explained the why behind supplement recommendations better. Love what your company is doing, keep it up.

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NAT1 (Detox)

Product features

Understanding Your NAT1 (Detox) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the NAT1 (Detox) gene do?

Why is the NAT1 (Detox) gene important?

What can I do based on my NAT1 (Detox) results?

How does the NAT1 (Detox) gene affect detoxification and cancer risk?

What do NAT1 genetic variants (SNPs) tell you in a NAT1 DNA test?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers