What does the IL13 (Allergies, Lung Function) gene do?

The IL13 (Allergies, Lung Function) gene provides instructions for making interleukin-13 (IL-13), a signaling protein (cytokine) used by your immune system. IL-13 is part of the “type 2” immune response, which helps the body respond to certain outside threats. It can also encourage immune cells to produce IgE antibodies—molecules that play a central role in many allergic reactions. In addition, IL-13 may influence the skin’s outer barrier by affecting filaggrin, a protein that helps keep the skin structured and better protected from allergens and irritants.

Why is the IL13 (Allergies, Lung Function) gene important?

IL13 is important because genetic differences in this gene can shift how strongly IL-13 signals in the body. Certain IL13 variants have been associated in research with higher IL-13 and/or IgE levels and have been linked to allergic and respiratory conditions such as allergic rhinitis (hay fever), asthma, eczema, and—depending on the specific variant and population studied—COPD and other inflammatory outcomes. While genes don’t determine your destiny, IL13 can help explain why some people are more prone to allergy-type immune responses or may be more sensitive to environmental triggers affecting breathing and skin comfort.

What can I do based on my IL13 (Allergies, Lung Function) results?

Based on your IL13 (Allergies, Lung Function) results, you’ll receive 3 personalized lifestyle recommendations aligned to your genotype. These recommendations focus on actionable steps—such as adjusting environmental exposures, building supportive daily routines for respiratory comfort, and reinforcing habits that support the skin barrier and immune balance. Your report is designed to help you prioritize what may matter most for you, based on the specific IL13 variants you carry.

How is the IL13 (Allergies, Lung Function) gene linked to asthma and hay fever?

IL13 influences a type 2 immune pathway that can increase IgE antibody activity, which is a key early step in many allergic reactions. Research on specific IL13 variants (for example, well-studied markers such as rs20541 and rs1800925) has found associations with higher IL-13 and/or IgE levels and increased risk of allergic rhinitis and asthma in certain groups. Because these effects can vary by variant and individual background, a DNA-based IL13 report helps translate the science into a more personalized picture of your potential tendencies—along with lifestyle guidance aimed at reducing trigger burden and supporting respiratory health.

What do IL13 (Allergies, Lung Function) genetic test results tell me about eczema and skin barrier health?

IL13 doesn’t just affect allergy signaling—it may also impact skin barrier function by reducing filaggrin, a protein that helps keep the outer skin layer strong and protective. When the barrier is compromised, allergens and irritants may penetrate more easily and interact with the immune system, potentially contributing to eczema risk or flare tendencies. Your IL13 gene report examines 7 variants and explains what your specific pattern may suggest, then provides personalized lifestyle recommendations that can help you focus on practical steps to support barrier-friendly routines and reduce exposure to common irritants.

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IL13 (Allergies, Lung Function)

Rated 4.67 out of 5 based on 12 customer ratings

4.7 (13 reviews)

IL13 (Allergies, Lung Function)

Rated 4.67 out of 5 based on 12 customer ratings

4.7 (13 reviews)

The report provides up to 3 personalized recommendations based on 7 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Trusted by 200,000+ users & 2,000+ doctors

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Analyzes 7 Genetic Variants

Up to 3 DNA-Based, Science-Backed Recommendations

IL13 (Allergies, Lung Function)

$59 $29

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Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your IL13 (Allergies, Lung Function) Variants: A DNA Gene Report

Do seasonal allergies hit you harder than they seem to for others—or do you deal with wheezing, tight chest, or stubborn congestion that’s hard to explain? Have you ever wondered why your skin reacts to certain triggers, or why asthma and eczema seem to run in families? Your IL13 (Allergies, Lung Function) gene helps regulate a key “type 2” immune pathway that can influence IgE antibody activity and the strength of your skin barrier—so understanding your IL13 variants can offer clearer, more personal insight into your allergy and respiratory tendencies.

Key Report Highlights

This IL13 (Allergies, Lung Function) Gene Report analyzes 7 clinically studied genetic variants (SNPs) and translates your results into 3 personalized, lifestyle-based recommendations. IL13 encodes interleukin-13 (IL-13), an immune signaling protein involved in type 2 (humoral) immunity that can stimulate IgE antibody release—an early step in many allergic reactions. A compelling insight: IL-13 may also reduce filaggrin, a structural protein that helps maintain the skin’s outer barrier, potentially making it easier for allergens to interact with the immune system.

Personalized, Actionable Recommendations

Your recommendations are tailored to your IL13 (Allergies, Lung Function) genotype—because risk and resilience can differ depending on which variants you carry and how they may influence IL-13 activity, IgE signaling, and barrier function. You’ll receive 3 personalized lifestyle recommendations designed to be practical and actionable. Examples of guidance that may be included: strategies to reduce exposure to common airborne triggers (like optimizing indoor air quality during peak pollen periods), and supportive habits for respiratory and skin barrier health (such as routines that help limit irritation and promote consistent recovery from environmental stressors).

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: The IL13 (Allergies, Lung Function) gene provides instructions for making interleukin-13 (IL-13), a signaling protein (cytokine) used by your immune system. IL-13 is part of the “type 2” immune response, which helps the body respond to certain outside threats. It can also encourage immune cells to produce IgE antibodies—molecules that play a central role in many allergic reactions. In addition, IL-13 may influence the skin’s outer barrier by affecting filaggrin, a protein that helps keep the skin structured and better protected from allergens and irritants.
: IL13 is important because genetic differences in this gene can shift how strongly IL-13 signals in the body. Certain IL13 variants have been associated in research with higher IL-13 and/or IgE levels and have been linked to allergic and respiratory conditions such as allergic rhinitis (hay fever), asthma, eczema, and—depending on the specific variant and population studied—COPD and other inflammatory outcomes. While genes don’t determine your destiny, IL13 can help explain why some people are more prone to allergy-type immune responses or may be more sensitive to environmental triggers affecting breathing and skin comfort.
: Based on your IL13 (Allergies, Lung Function) results, you’ll receive 3 personalized lifestyle recommendations aligned to your genotype. These recommendations focus on actionable steps—such as adjusting environmental exposures, building supportive daily routines for respiratory comfort, and reinforcing habits that support the skin barrier and immune balance. Your report is designed to help you prioritize what may matter most for you, based on the specific IL13 variants you carry.
: IL13 influences a type 2 immune pathway that can increase IgE antibody activity, which is a key early step in many allergic reactions. Research on specific IL13 variants (for example, well-studied markers such as rs20541 and rs1800925) has found associations with higher IL-13 and/or IgE levels and increased risk of allergic rhinitis and asthma in certain groups. Because these effects can vary by variant and individual background, a DNA-based IL13 report helps translate the science into a more personalized picture of your potential tendencies—along with lifestyle guidance aimed at reducing trigger burden and supporting respiratory health.
: IL13 doesn’t just affect allergy signaling—it may also impact skin barrier function by reducing filaggrin, a protein that helps keep the outer skin layer strong and protective. When the barrier is compromised, allergens and irritants may penetrate more easily and interact with the immune system, potentially contributing to eczema risk or flare tendencies. Your IL13 gene report examines 7 variants and explains what your specific pattern may suggest, then provides personalized lifestyle recommendations that can help you focus on practical steps to support barrier-friendly routines and reduce exposure to common irritants.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.67 out of 5 based on 12 customer ratings

4.7 (13 reviews)

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Chad P.

Rated 5 out of 5
Been through a few of these DNA insights and the allergies one is probably the most actionable for me so far. I really liked how it called out things I wouldn’t have caught on my own. Always impressed.
Tom G.

Rated 5 out of 5
IL13 explained my pollen cough.
Nolan K.

Rated 4 out of 5
Helpful, but mold tips.
Hazel F.

Rated 4 out of 5
I got the IL13 (Allergies, Lung Function) report because spring allergies always hit my chest, not just my nose. The explanation of how IL13 can relate to airway inflammation made the results feel less random. The lifestyle section was the best part, I added an air purifier in my bedroom and started avoiding outdoor runs on high pollution days. I do wish it included a bit more detail on how to track mold exposure in older apartments, or a simple checklist. Still, it gave me practical steps and I noticed fewer night coughs.
Amanda L.

Rated 5 out of 5
Air purifier, fewer wheezes.

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IL13 (Allergies, Lung Function)

Product features

Understanding Your IL13 (Allergies, Lung Function) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the IL13 (Allergies, Lung Function) gene do?

Why is the IL13 (Allergies, Lung Function) gene important?

What can I do based on my IL13 (Allergies, Lung Function) results?

How is the IL13 (Allergies, Lung Function) gene linked to asthma and hay fever?

What do IL13 (Allergies, Lung Function) genetic test results tell me about eczema and skin barrier health?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers