What does the LHCGR (Sex Hormones) gene do?

The LHCGR (Sex Hormones) gene provides instructions for building the luteinizing hormone/chorionic gonadotropin receptor. This receptor sits on certain cells and helps your body respond to luteinizing hormone (LH) and human chorionic gonadotropin (hCG). In women, LH signaling is central to ovulation and menstrual cycle regulation. In men, LH signaling supports testosterone production, which is important for sperm production and reproductive function.

Why is the LHCGR (Sex Hormones) gene important?

LHCGR is important because it helps translate major reproductive hormone signals into real biological actions—like ovulation in women and testosterone production in men. Research has linked specific LHCGR variants (including rs13405728 and rs2293275) to differences in PCOS risk and related hormone patterns (such as higher testosterone in some groups), and to variation in reproductive outcomes in certain assisted reproductive technology contexts. Knowing your genotype can help you understand whether you may have inherited genetic patterns associated with altered sex-hormone signaling.

What can I do based on my LHCGR (Sex Hormones) results?

Based on your LHCGR results, you’ll receive 3 personalized recommendations focused on actionable support—primarily lifestyle and supplement guidance. These recommendations are tailored to your genotype and may include steps to support healthy metabolic markers often discussed alongside hormone balance (such as triglycerides and LDL cholesterol in PCOS-related research), as well as supplement options that align with your reported genetic patterns. Your report is designed to help you make more informed, personalized choices and to identify topics you may want to discuss with a clinician, especially if you’re managing PCOS symptoms or fertility planning.

Is the LHCGR gene linked to PCOS and high testosterone?

Studies have associated several LHCGR variants with PCOS risk and related hormone patterns. For example, the major “A” allele of rs13405728 has been linked in multiple studies to increased PCOS risk, and some research reports higher testosterone and less favorable lipid markers (like triglycerides and LDL cholesterol) in certain carriers with PCOS. Another widely studied variant, rs2293275, has been associated with PCOS risk and progression, with reports of higher testosterone and differences in LH-related measures in women with PCOS. A DNA report can’t diagnose PCOS, but it can clarify whether you carry genetic variants that research has associated with PCOS-related hormone signaling patterns.

What can LHCGR genetic testing tell me about fertility and response to fertility treatment?

LHCGR genetic testing can provide insight into inherited differences in how the body may respond to LH and hCG signaling—pathways that influence ovulation, ovarian response, and testosterone production. Research has linked certain LHCGR variants (such as rs2293275 and rs13405728) to differences in ovarian aging, ovarian hyperstimulation risk, and outcomes in assisted reproductive technology in some populations, as well as differing reproductive risks and protections reported in men for specific outcomes. Your report summarizes the evidence for the variants tested and pairs your genotype with personalized lifestyle and supplement recommendations to support reproductive and hormone health, while emphasizing that clinical decisions should be made with a qualified healthcare professional.

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LHCGR (Sex Hormones)

Rated 4.83 out of 5 based on 6 customer ratings

4.8 (7 reviews)

LHCGR (Sex Hormones)

Rated 4.83 out of 5 based on 6 customer ratings

4.8 (7 reviews)

The report provides up to 3 personalized recommendations based on 5 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Trusted by 200,000+ users & 2,000+ doctors

Proven track record: 3+ million analyses delivered

Analyzes 5 Genetic Variants

Up to 3 DNA-Based, Science-Backed Recommendations

LHCGR (Sex Hormones)

$59 $29

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Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your LHCGR (Sex Hormones) Variants: A DNA Gene Report

Do your hormones feel like a moving target—irregular cycles, signs of high androgens, or unexplained fertility challenges? Have you ever wondered why two people can follow the same lifestyle plan yet see very different results in ovulation, testosterone, or response to fertility treatments? Your LHCGR (Sex Hormones) gene helps your body “hear” key reproductive signals (LH and hCG), and understanding your LHCGR variants can reveal personalized clues about hormone balance, PCOS-related risk patterns, and reproductive health.

Key Report Highlights

This LHCGR (Sex Hormones) Gene Report analyzes 5 well-studied variants (SNPs) tied to sex-hormone signaling and reproductive outcomes, then delivers 3 personalized recommendations tailored to your genotype. LHCGR encodes the luteinizing hormone/chorionic gonadotropin receptor—an essential switch that helps regulate ovulation and menstrual cycle timing in women and testosterone production in men. A compelling takeaway: differences in LHCGR signaling have been associated in research with PCOS risk and hormone-related biomarkers such as testosterone and lipid levels in certain carriers.

Personalized, Actionable Recommendations

Your results aren’t generic—they’re based on your specific LHCGR genotype across the tested variants, translating genetic findings into practical, personalized next steps. You’ll receive a set of 3 targeted recommendations spanning lifestyle and supplement guidance, designed to support healthy sex-hormone signaling and related metabolic factors. Examples of the kind of advice you may see include lifestyle strategies that support insulin sensitivity and lipid balance (often relevant in PCOS patterns), and supplement suggestions selected to complement hormone and metabolic goals—always tailored to your genetic findings and presented as supportive, not diagnostic, guidance.

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: The LHCGR (Sex Hormones) gene provides instructions for building the luteinizing hormone/chorionic gonadotropin receptor. This receptor sits on certain cells and helps your body respond to luteinizing hormone (LH) and human chorionic gonadotropin (hCG). In women, LH signaling is central to ovulation and menstrual cycle regulation. In men, LH signaling supports testosterone production, which is important for sperm production and reproductive function.
: LHCGR is important because it helps translate major reproductive hormone signals into real biological actions—like ovulation in women and testosterone production in men. Research has linked specific LHCGR variants (including rs13405728 and rs2293275) to differences in PCOS risk and related hormone patterns (such as higher testosterone in some groups), and to variation in reproductive outcomes in certain assisted reproductive technology contexts. Knowing your genotype can help you understand whether you may have inherited genetic patterns associated with altered sex-hormone signaling.
: Based on your LHCGR results, you’ll receive 3 personalized recommendations focused on actionable support—primarily lifestyle and supplement guidance. These recommendations are tailored to your genotype and may include steps to support healthy metabolic markers often discussed alongside hormone balance (such as triglycerides and LDL cholesterol in PCOS-related research), as well as supplement options that align with your reported genetic patterns. Your report is designed to help you make more informed, personalized choices and to identify topics you may want to discuss with a clinician, especially if you’re managing PCOS symptoms or fertility planning.
: Studies have associated several LHCGR variants with PCOS risk and related hormone patterns. For example, the major “A” allele of rs13405728 has been linked in multiple studies to increased PCOS risk, and some research reports higher testosterone and less favorable lipid markers (like triglycerides and LDL cholesterol) in certain carriers with PCOS. Another widely studied variant, rs2293275, has been associated with PCOS risk and progression, with reports of higher testosterone and differences in LH-related measures in women with PCOS. A DNA report can’t diagnose PCOS, but it can clarify whether you carry genetic variants that research has associated with PCOS-related hormone signaling patterns.
: LHCGR genetic testing can provide insight into inherited differences in how the body may respond to LH and hCG signaling—pathways that influence ovulation, ovarian response, and testosterone production. Research has linked certain LHCGR variants (such as rs2293275 and rs13405728) to differences in ovarian aging, ovarian hyperstimulation risk, and outcomes in assisted reproductive technology in some populations, as well as differing reproductive risks and protections reported in men for specific outcomes. Your report summarizes the evidence for the variants tested and pairs your genotype with personalized lifestyle and supplement recommendations to support reproductive and hormone health, while emphasizing that clinical decisions should be made with a qualified healthcare professional.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.83 out of 5 based on 6 customer ratings

4.8 (7 reviews)

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Ellis T.

Rated 5 out of 5
I’m 38 and started the LHCGR (Sex Hormones) report because my testosterone and libido were all over the place after a stressful year. The section on avoiding endocrine disruptors made it practical, I swapped out fragranced products, stopped microwaving in plastic, and checked labels more carefully. The note about avoiding organochlorine pesticide exposure pushed me to prioritize certain produce choices and wash routines. I also added indole-3-carbinol and tracked how I felt for a month. My energy and mood feel steadier, and I’m not guessing anymore, I have a clear, gene-based checklist.
Sarah F.

Rated 5 out of 5
Ich habe den LHCGR (Sex Hormones) Bericht gekauft, weil in meiner Familie PCOS und Zyklusprobleme häufig sind und ich selbst mit Stimmungsschwankungen vor der Periode kämpfe. Besonders hilfreich war die klare Erklärung, wie Umweltfaktoren wie endokrine Disruptoren das Hormonsystem zusätzlich belasten können. Ich habe Parfüm und Weichmacher im Haushalt reduziert und achte gezielt auf mögliche organochlorierte Pestizide, z.B. bei bestimmten Lebensmitteln. Außerdem habe ich Indol-3-Carbinol ausprobiert, wie empfohlen. Nach einigen Wochen fühlten sich meine PMS-Tage weniger heftig an und ich hatte das Gefühl, endlich einen konkreten Plan zu haben.
Ian M.

Rated 5 out of 5
Honestly, I was skeptical about these DNA health things, but the sex hormones one actually helped. The advice to avoid certain pesticides and try indole-3-carbinol made sense, and when I implemented them, I noticed some subtle improvements. Definitely more useful than I expected.
Jaxon K.

Rated 4 out of 5
Useful LHCGR insights on endocrine disruptors, but I wanted a bit more guidance on indole-3-carbinol timing and typical dose ranges.
Adrian C.

Rated 5 out of 5
Phthalate purge, calmer libido.

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LHCGR (Sex Hormones)

Product features

Understanding Your LHCGR (Sex Hormones) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the LHCGR (Sex Hormones) gene do?

Why is the LHCGR (Sex Hormones) gene important?

What can I do based on my LHCGR (Sex Hormones) results?

Is the LHCGR gene linked to PCOS and high testosterone?

What can LHCGR genetic testing tell me about fertility and response to fertility treatment?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers