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Medication Check (PGx testing)

Explains how your DNA affects your body’s response to medications. It covers 50 drugs, offering guidance on whether you can follow standard precautions or should exercise extra caution. View sample report.
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Proven track record: 3+ million analyses delivered

Trusted by 200,000+ users & 2,000+ doctors

Proven track record: 3+ million analyses delivered

Demonstrates how gene variants affect drug metabolism
Covers over 50 medications
Insights based on CPIC and FDA guidelines
Dosing and side effect information

Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

 

Are you uncertain about how well standard dosages of certain drugs will work for you? Do you want to know whether you’re more prone to adverse effects from common pain relievers, anticoagulants, or antidepressants? The Medication Check (PGx testing) report provides clarity by analyzing your genetic variants and showing how they may influence your reaction to over 50 medications.

 

Understanding Your Genetic Response to Medications

Unlike a one-size-fits-all approach, this genetic test highlights if you might need a lower dose, an alternative drug, or simply more vigilant monitoring. Each gene-drug interaction is explained in an accessible format, so you’ll see at a glance whether you fall under “Standard Precautions” or “Use With Caution.” If the report flags a potential for adverse events, it indicates where adjustments may be warranted – information you can share with your doctor or pharmacist.

This report analyzes your genetic variants to predict how your body might respond to these 50 medications:

  1. Anesthesiology
      • Anesthetics: Volatile Anesthetics (Desflurane, Enflurane, Halothane, Isoflurane, Methoxyflurane, Sevoflurane)
      • Skeletal Muscle Relaxants: Succinylcholine
  • Cardiovascular
      • Antiplatelets & Anticoagulants: Acenocoumarol, Clopidogrel, Phenprocoumon, Warfarin
      • Statins: Atorvastatin, Fluvastatin, Lovastatin, Pitavastatin, Pravastatin, Rosuvastatin, Simvastatin
  • Gastrointestinal
      • Proton Pump Inhibitors: Dexlansoprazole, Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole
  • Immunology, Rheumatology & Oncology
      • Antihyperuricemic & Antigout Agents: Allopurinol
      • Antimetabolites: Capecitabine, Fluorouracil, Mercaptopurine, Tegafur
      • Immunosuppressants: Azathioprine, Methotrexate, Siponimod, Tacrolimus
  • Infections
      • Antifungals: Voriconazole
      • Antivirals: Efavirenz, Nevirapine, Triple therapy (peginterferon alfa-2a/b & ribavirin)
  • Pain
      • NSAIDs: Celecoxib, Flurbiprofen, Ibuprofen, Lornoxicam, Meloxicam, Piroxicam, Tenoxicam
      • Opioids: Methadone
  • Psychotropic
    • Antidepressants: Amitriptyline, Bupropion, Citalopram, Clomipramine, Doxepin, Escitalopram, Imipramine, Sertraline, Trimipramine
    • Antiepileptics: Phenytoin
    • Antipsychotics: Quetiapine

 

Evidence-Based Insights

By consolidating guidelines from leading pharmacogenomics authorities, the report allows you to see where research-based consensus supports certain dosing adjustments. This evidence-based approach empowers you to collaborate with your healthcare team in tailoring treatments more precisely.

 

Reducing Uncertainty

Even if no major genetic red flags appear, the Drug Check (PGx Test) Report reduces guesswork. You’ll know your baseline risk for things like muscle pain from certain statins or reduced effectiveness of certain proton pump inhibitors (acid reducers), enhancing your confidence in treatment choices.

 

Important Note

This report is for informational purposes only. It does not replace professional medical advice, and you should always consult with a qualified healthcare provider before making medication decisions. Genetics is just one piece of the puzzle – factors like age, body weight, and other medications also play a role in how your body handles drugs.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

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  1. Josh

    I’ve had recurring severe allergies and inconsistent responses to antihistamines and steroids. This report identified relevant HLA gene variants that influence immune response and drug efficacy. The tailored suggestions helped my allergist find the most effective treatment with minimal side effects. It’s detailed yet very approachable, a great resource for allergy sufferers.

  2. Ryan

    Before my doctor prescribes anything new, we review this Pharmacogenomics report together. It highlights my genetic strengths and vulnerabilities, particularly in enzymes like CYP1A2 and CYP2C19. Knowing this upfront has prevented adverse reactions and guided safer medication choices. The clear visuals and prioritized drug lists make it easy to use in clinical discussions.

  3. Paraone

    With Type 2 diabetes, medication management is critical. This report highlighted variants in my SLC22A1 and CYP2C9 genes that affect metformin and sulfonylurea metabolism. My endocrinologist adjusted my prescriptions accordingly, leading to better glucose control and fewer side effects. The report is comprehensive and a fantastic tool for personalized medicine.

  4. Donalee

    I often experienced unexpected drug side effects without knowing why. This report pinpointed my NAT2 slow acetylator genotype, explaining the issues with certain antibiotics and painkillers. The practical advice on avoiding or adjusting dosages has made a huge difference in my quality of life. The blend of science and real world application is exceptional.

  5. Dan

    This Pharmacogenomics report unlocked why I responded poorly to SSRIs and antipsychotics; my CYP2C19 ultra rapid metabolizer status was the key. Switching to medications aligned with my genetic profile has been life transforming. I appreciate the detailed drug gene interaction charts and easy to follow guidance that improved my mental health treatment significantly.

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