Why do I need this report?

If you’ve had Lyme disease and still feel unwell after treatment, it can be hard to know what to focus on next. While genetics doesn’t appear to strongly influence the chance of getting Lyme (tick exposure is the biggest driver), research suggests genetics may affect how some people experience lingering post-treatment symptoms—especially joint pain and inflammation. This report helps you identify whether variants in immune and inflammation-related pathways (and toxin transport) may be relevant for you, so you can prioritize supportive strategies that match your biology.

Why is this report unique?

Most Lyme resources focus on exposure risk and acute infection. This report is different: it focuses on what your DNA may reveal about post-treatment symptom drivers. It evaluates 5 specific genetic variants across pathways tied to immune response, inflammation, and handling of bacterial byproducts, then turns those findings into 12 personalized recommendations you can use right away—covering dietary, lifestyle, and supplement options.

How is the recommendations list built?

Your recommendations list is built by combining (1) the predicted impact of your specific variants on relevant biological pathways (such as innate immune signaling and inflammatory tone) with (2) the strength and consistency of the supporting scientific evidence. Recommendations are then prioritized so the most genetically relevant, evidence-aligned, and generally safe actions appear first, with additional options provided for deeper personalization. Because research on chronic post-treatment Lyme symptoms is still evolving and sometimes mixed, the report also flags uncertainty where appropriate so you can interpret results responsibly.

Can genetics influence chronic Lyme symptoms after antibiotic treatment?

Genetics doesn’t seem to play a major role in whether you get Lyme disease in the first place—exposure to infected ticks is the primary risk factor. However, studies suggest that in some people, genetic differences may influence immune signaling and inflammatory responses that relate to persistent post-treatment symptoms, particularly joint pain. This report focuses on variants in genes involved in immune response and inflammation (including TLR-related and HLA pathways) as well as transport mechanisms that may affect how the body handles bacterial byproducts. The goal is not to diagnose PTLDS, but to provide personalized insight that can help you choose supportive strategies more intelligently.

What genes are included in a Chronic Lyme DNA report?

The Chronic Lyme DNA Report analyzes 5 variants in genes studied in relation to immune response, inflammation, and the handling of bacterial components and byproducts. These include genes involved in innate immune recognition and inflammatory signaling (such as TLR pathway genes), immune presentation and regulation (such as HLA-related genes), and transport processes (such as ABCB1). Because the science is still emerging and results across studies can be mixed, the report explains what is known, what is uncertain, and how to use your results as one input—alongside symptoms, medical history, and clinician guidance.

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Chronic Lyme

Rated 4.80 out of 5 based on 5 customer ratings

4.8 (6 reviews)

Chronic Lyme

Rated 4.80 out of 5 based on 5 customer ratings

4.8 (6 reviews)

The report provides up to 12 personalized recommendations based on 5 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Trusted by 200,000+ users & 2,000+ doctors

Proven track record: 3+ million analyses delivered

Analyzes 5 Genetic Variants

Up to 12 DNA-Based, Science-Backed Recommendations

Chronic Lyme

$59 $29

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Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your Chronic Lyme Risks: A DNA-Based Report

Still dealing with fatigue, joint aches, or brain fog long after Lyme treatment? Wondering why your symptoms linger while others recover more quickly? Looking for a clearer, more personalized way to support your immune and inflammatory response moving forward? The Chronic Lyme DNA Report is designed to help you understand how your genetics may influence post-treatment symptom patterns—so you can make more targeted, confident health decisions.

Key Report Highlights

This report analyzes 5 research-backed genetic variants connected to immune signaling, inflammation, and the body’s handling of bacterial byproducts—areas that may influence persistent symptoms such as joint pain after treatment. You’ll also receive 12 personalized recommendations to help guide next steps. Notably, a subset of people continue to experience symptoms for months or even years after standard antibiotic therapy—often described as post-treatment Lyme disease syndrome (PTLDS)—highlighting the need for individualized support beyond one-size-fits-all approaches.

Personalized, Actionable Recommendations

Your recommendations are personalized to your genetic findings and organized into practical categories: dietary, lifestyle, and supplement strategies. For example, your plan may include diet guidance that supports a balanced inflammatory response (such as emphasizing omega-3-rich foods and polyphenol-containing plants), lifestyle steps that reinforce recovery and resilience (like sleep optimization and pacing strategies to avoid post-exertional symptom flares), and targeted supplement considerations aligned with your immune-response genetics. Every suggestion is written to be actionable, with clear rationale and safety notes.

User-Friendly Format and Trust

The user-friendly format of this report emphasizes clarity, offering practical, easy-to-follow insights to integrate seamlessly into your lifestyle. Whether you’re a novice or seasoned biohacker, you’ll find the layout accessible and the information straightforward.

This report is grounded in the latest scientific research and trusted by over 150,000 users and 1,000+ doctors worldwide. It’s not only comprehensive but also complies with stringent privacy laws, being HIPAA and GDPR compliant.

Getting Started

Ready to unlock the secrets within your DNA? Purchase a DNA kit for an easy at-home collection process and gain the insights you need for a proactive, personalized approach to wellness. Don’t wait—take the first step to understanding your health today.

Product FAQs

: If you’ve had Lyme disease and still feel unwell after treatment, it can be hard to know what to focus on next. While genetics doesn’t appear to strongly influence the chance of getting Lyme (tick exposure is the biggest driver), research suggests genetics may affect how some people experience lingering post-treatment symptoms—especially joint pain and inflammation. This report helps you identify whether variants in immune and inflammation-related pathways (and toxin transport) may be relevant for you, so you can prioritize supportive strategies that match your biology.
: Most Lyme resources focus on exposure risk and acute infection. This report is different: it focuses on what your DNA may reveal about post-treatment symptom drivers. It evaluates 5 specific genetic variants across pathways tied to immune response, inflammation, and handling of bacterial byproducts, then turns those findings into 12 personalized recommendations you can use right away—covering dietary, lifestyle, and supplement options.
: Your recommendations list is built by combining (1) the predicted impact of your specific variants on relevant biological pathways (such as innate immune signaling and inflammatory tone) with (2) the strength and consistency of the supporting scientific evidence. Recommendations are then prioritized so the most genetically relevant, evidence-aligned, and generally safe actions appear first, with additional options provided for deeper personalization. Because research on chronic post-treatment Lyme symptoms is still evolving and sometimes mixed, the report also flags uncertainty where appropriate so you can interpret results responsibly.
: Genetics doesn’t seem to play a major role in whether you get Lyme disease in the first place—exposure to infected ticks is the primary risk factor. However, studies suggest that in some people, genetic differences may influence immune signaling and inflammatory responses that relate to persistent post-treatment symptoms, particularly joint pain. This report focuses on variants in genes involved in immune response and inflammation (including TLR-related and HLA pathways) as well as transport mechanisms that may affect how the body handles bacterial byproducts. The goal is not to diagnose PTLDS, but to provide personalized insight that can help you choose supportive strategies more intelligently.
: The Chronic Lyme DNA Report analyzes 5 variants in genes studied in relation to immune response, inflammation, and the handling of bacterial components and byproducts. These include genes involved in innate immune recognition and inflammatory signaling (such as TLR pathway genes), immune presentation and regulation (such as HLA-related genes), and transport processes (such as ABCB1). Because the science is still emerging and results across studies can be mixed, the report explains what is known, what is uncertain, and how to use your results as one input—alongside symptoms, medical history, and clinician guidance.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.80 out of 5 based on 5 customer ratings

4.8 (6 reviews)

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Angela L.

Rated 5 out of 5
I never write reviews, but I just had to for this one. Wasn’t expecting to get such specific advice, especially about things like lingonberry and probiotics. Honestly, I feel more prepared to manage my inflammation now.
Emi L.

Rated 5 out of 5
Honestly, I was stuck with what to do for my chronic fatigue, but after following the tips here, I finally feel some relief.
Tyrone A.

Rated 4 out of 5
Lyme inflammation map, almost perfect.
Jack E.

Rated 5 out of 5
Este informe me sorprendió gratamente. Los consejos sobre suplementos y evitar desencadenantes fueron claros y fáciles de seguir. Noté mejoras en mi bienestar general y valoro mucho la personalización según mis necesidades. ¡Muy recomendable!
Priti G.

Rated 5 out of 5
I actually learned something new about which foods to avoid. Didn’t expect that from a DNA test.

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Chronic Lyme

Product features

Understanding Your Chronic Lyme Risks: A DNA-Based Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

Why do I need this report?

Why is this report unique?

How is the recommendations list built?

Can genetics influence chronic Lyme symptoms after antibiotic treatment?

What genes are included in a Chronic Lyme DNA report?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers