What does the ANKRD55 (Autoimmune) gene do?

ANKRD55 encodes a protein called ankyrin repeat domain 55. While its full function isn’t completely understood, it’s abundant in immune-related tissues (like lymph nodes) and has been strongly associated with autoimmune disease risk in genetic studies. Because of these links, ANKRD55 is thought to be involved in inflammatory signaling—how the immune system “turns up” or “turns down” inflammatory responses.

Why is the ANKRD55 (Autoimmune) gene important?

ANKRD55 is important because genetic variants in and around this gene have repeatedly been linked to autoimmune conditions such as multiple sclerosis, Crohn’s disease, and rheumatoid arthritis. Research suggests some ANKRD55 variants may influence inflammatory pathways, including signals involving IL-6 (a cytokine often elevated in rheumatoid arthritis). In studies, certain minor variants in ANKRD55 have been associated with a decreased risk of rheumatoid arthritis, potentially by reducing IL-6 production and other inflammatory signals.

What can I do based on my ANKRD55 (Autoimmune) results?

Based on your ANKRD55 (Autoimmune) results, you’ll receive 4 personalized recommendations designed to be actionable and relevant to your genotype. These include dietary and supplement guidance aimed at supporting healthy inflammatory signaling and immune balance. Your report helps you understand which evidence-informed strategies may be more relevant for you—so you can focus your efforts on the areas most aligned with your DNA results.

How is ANKRD55 linked to rheumatoid arthritis and inflammation?

Genetic studies have repeatedly connected ANKRD55 to autoimmune disease risk, including rheumatoid arthritis. One key inflammatory signal implicated in rheumatoid arthritis is IL-6, which is often elevated in patients and can contribute to joint tissue damage. ANKRD55 sits near IL6ST, a gene involved in cytokine signaling (including IL-6 pathways), and certain ANKRD55 minor variants—such as the ‘A’ allele of rs71624119, rs7731626, and rs10040327, and the ‘T’ allele of rs10065637—have been associated with a decreased risk of rheumatoid arthritis in published research. These variants may reduce IL-6 production and related inflammatory signaling, which could help explain the observed protective association.

What does ANKRD55 genetic testing include in a DNA report?

An ANKRD55-focused DNA report typically analyzes specific single nucleotide polymorphisms (SNPs) that research has linked to inflammation and autoimmunity. This report evaluates 4 ANKRD55 variants and explains what your genotype may suggest about inflammatory signaling patterns, including pathways related to IL-6. It then translates your results into 4 personalized recommendations—centered on dietary and supplement strategies—so you can apply your genetic insights in practical, day-to-day decisions.

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ANKRD55 (Autoimmune)

Rated 4.70 out of 5 based on 10 customer ratings

4.7 (11 reviews)

ANKRD55 (Autoimmune)

Rated 4.70 out of 5 based on 10 customer ratings

4.7 (11 reviews)

The report provides up to 4 personalized recommendations based on 4 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Analyzes 4 Genetic Variants

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ANKRD55 (Autoimmune)

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Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your ANKRD55 (Autoimmune) Variants: A DNA Gene Report

Do you ever wonder why your body seems to “run hot” with inflammation, or why autoimmune conditions show up in some families but not others? Have you been curious whether your genes may influence key immune signals like IL-6—one of the messengers tied to chronic inflammation? The ANKRD55 (Autoimmune) gene is strongly linked to immune activity, and understanding your ANKRD55 variants can help you make more informed, personalized choices to support healthy inflammatory balance.

Key Report Highlights

This ANKRD55 (Autoimmune) Gene Report analyzes 4 research-backed genetic variants (SNPs) and translates your results into 4 personalized recommendations. ANKRD55 is highly active in immune tissues and is believed to play a role in inflammatory signaling—partly through its proximity to IL6ST, a gene involved in how cytokines like IL-6 communicate with cells. A compelling takeaway from the research: certain ANKRD55 minor variants have been associated with a decreased risk of rheumatoid arthritis, potentially by lowering IL-6 and related inflammatory signals.

Personalized, Actionable Recommendations

Your results aren’t presented as generic wellness tips—they’re tailored to your ANKRD55 (Autoimmune) genotype and the specific variants you carry. You’ll receive 4 personalized recommendations focused on dietary and supplement strategies that align with your genetic inflammation profile. For example, your report may highlight diet patterns and food choices commonly used to support healthy inflammatory signaling, and it may suggest supplement options that support immune balance—along with practical guidance on how to prioritize them based on your genetics.

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: ANKRD55 encodes a protein called ankyrin repeat domain 55. While its full function isn’t completely understood, it’s abundant in immune-related tissues (like lymph nodes) and has been strongly associated with autoimmune disease risk in genetic studies. Because of these links, ANKRD55 is thought to be involved in inflammatory signaling—how the immune system “turns up” or “turns down” inflammatory responses.
: ANKRD55 is important because genetic variants in and around this gene have repeatedly been linked to autoimmune conditions such as multiple sclerosis, Crohn’s disease, and rheumatoid arthritis. Research suggests some ANKRD55 variants may influence inflammatory pathways, including signals involving IL-6 (a cytokine often elevated in rheumatoid arthritis). In studies, certain minor variants in ANKRD55 have been associated with a decreased risk of rheumatoid arthritis, potentially by reducing IL-6 production and other inflammatory signals.
: Based on your ANKRD55 (Autoimmune) results, you’ll receive 4 personalized recommendations designed to be actionable and relevant to your genotype. These include dietary and supplement guidance aimed at supporting healthy inflammatory signaling and immune balance. Your report helps you understand which evidence-informed strategies may be more relevant for you—so you can focus your efforts on the areas most aligned with your DNA results.
: Genetic studies have repeatedly connected ANKRD55 to autoimmune disease risk, including rheumatoid arthritis. One key inflammatory signal implicated in rheumatoid arthritis is IL-6, which is often elevated in patients and can contribute to joint tissue damage. ANKRD55 sits near IL6ST, a gene involved in cytokine signaling (including IL-6 pathways), and certain ANKRD55 minor variants—such as the ‘A’ allele of rs71624119, rs7731626, and rs10040327, and the ‘T’ allele of rs10065637—have been associated with a decreased risk of rheumatoid arthritis in published research. These variants may reduce IL-6 production and related inflammatory signaling, which could help explain the observed protective association.
: An ANKRD55-focused DNA report typically analyzes specific single nucleotide polymorphisms (SNPs) that research has linked to inflammation and autoimmunity. This report evaluates 4 ANKRD55 variants and explains what your genotype may suggest about inflammatory signaling patterns, including pathways related to IL-6. It then translates your results into 4 personalized recommendations—centered on dietary and supplement strategies—so you can apply your genetic insights in practical, day-to-day decisions.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
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A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.70 out of 5 based on 10 customer ratings

4.7 (11 reviews)

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Nia D.

Rated 5 out of 5
Arachidonic swap, fewer flares.
Mia F.

Rated 3 out of 5
Useful, but the autoimmune risk language felt a bit alarming, and I wanted more context on how strong ANKRD55 is compared to other factors.
Glenn H.

Rated 5 out of 5
Honestly, I didn’t realize how much my genes could affect inflammation. The food suggestions made me rethink my meals.
Vanessa A.

Rated 5 out of 5
As a runner in my late 20s, I kept blaming training for my recurring tendon irritation, but the ANKRD55 (Autoimmune) report pushed me to look at inflammation differently. It laid out why an autoimmune-leaning profile might respond better to an anti-inflammatory diet, not just more rest days. I followed the “reduce arachidonic acid” guidance by cutting back on processed meats and certain cooking oils, and I added more polyphenol rich foods like berries and extra virgin olive oil. With curcumin added, my post run swelling calmed within a few weeks.
Luis A.

Rated 5 out of 5
There’s a lot of great information here, especially about diet changes and supplements. I liked that it explained why certain foods matter for inflammation. The only thing I wish is that it was a little less technical in some places, I had to Google some terms to fully get it.

ANKRD55 (Autoimmune)

Product features

Understanding Your ANKRD55 (Autoimmune) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the ANKRD55 (Autoimmune) gene do?

Why is the ANKRD55 (Autoimmune) gene important?

What can I do based on my ANKRD55 (Autoimmune) results?

How is ANKRD55 linked to rheumatoid arthritis and inflammation?

What does ANKRD55 genetic testing include in a DNA report?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers