What does the ABCB1 (Chronic Lyme) gene do?

ABCB1 (sometimes called MDR1) provides instructions for making P-glycoprotein (P-gp), a transport protein that acts like a cellular bouncer. Its job is to move certain foreign compounds (including xenobiotics and pathogen-related molecules) out of cells. This transport function can shape how your body handles bacterial components after infections and can also affect how some medications are absorbed, distributed, and cleared.

Why is the ABCB1 (Chronic Lyme) gene important?

ABCB1 (Chronic Lyme) matters because genetic variants can change how active P-glycoprotein is. Research suggests that variants associated with reduced P-gp activity may be linked to a higher likelihood of persistent symptoms after a Borrelia burgdorferi infection (often referred to as chronic Lyme or PTLDS). Separately, ABCB1 variants can influence medication response—some people may require different dosing considerations or may not respond as expected to certain drugs because P-gp can alter how much medication reaches target tissues.

What can I do based on my ABCB1 (Chronic Lyme) results?

Based on your ABCB1 (Chronic Lyme) results, you’ll receive 3 personalized recommendations with actionable next steps. These include dietary and supplement guidance tailored to your genotype, with a focus on supporting immune function, healthy inflammatory balance, and recovery resilience. Your recommendations may include targeted nutrition priorities (e.g., specific food patterns that support inflammatory signaling) and supplement suggestions aligned with your genetic profile and goals. This report is educational and can also help you have more informed conversations with your clinician—especially if you’re navigating persistent symptoms or medication effectiveness concerns.

Can ABCB1 genetic variants increase the risk of chronic Lyme symptoms?

They may contribute to risk in some people. Studies have linked certain ABCB1 genetic variants—particularly those associated with reduced P-glycoprotein (P-gp) activity—to a higher likelihood of persistent symptoms after an acute Borrelia infection (often described as chronic Lyme or post-treatment Lyme disease syndrome, PTLDS). P-gp helps transport certain foreign or pathogen-related compounds out of cells, which may influence how the immune system is exposed to bacterial components and how inflammation is regulated over time. Genetics are only one piece of the puzzle, but knowing your ABCB1 profile can add personalized context to your immune and inflammation tendencies.

What does an ABCB1 (Chronic Lyme) DNA test tell me about medication response?

This report can help explain why medication effects may differ from person to person. ABCB1 influences P-glycoprotein, which can affect how much of certain medications are absorbed and how much reaches specific tissues. Some ABCB1 genetic variants are associated with higher P-gp activity, which may reduce the effective concentration of certain drugs—potentially contributing to weaker response or the need for clinician-guided adjustments. While this report is not a prescription tool, it provides a genetics-informed layer of insight you can use to discuss treatment options, side effects, and response patterns with a qualified healthcare professional.

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ABCB1 (Chronic Lyme)

Rated 5.00 out of 5 based on 8 customer ratings

5.0 (9 reviews)

ABCB1 (Chronic Lyme)

Rated 5.00 out of 5 based on 8 customer ratings

5.0 (9 reviews)

The report provides up to 3 personalized recommendations based on your genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Trusted by 200,000+ users & 2,000+ doctors

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Analyzes Key Genetic Variants

Up to 3 DNA-Based, Science-Backed Recommendations

ABCB1 (Chronic Lyme)

$59 $29

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Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your ABCB1 (Chronic Lyme) Variants: A DNA Gene Report

Have you ever wondered why some people bounce back after Lyme disease while others struggle with lingering fatigue, aches, or “brain fog” for months or even years? Are you curious whether your body may clear bacterial byproducts less efficiently—or whether certain medications might not work as expected for you? Your ABCB1 (Chronic Lyme) gene helps govern a key cellular “pump” involved in moving unwanted compounds out of cells, and understanding your ABCB1 genetic variants can offer valuable, personalized insight into inflammation, immune resilience, and how your body may respond to specific therapies.

Key Report Highlights

This DNA report analyzes genetic variants in the ABCB1 (Chronic Lyme) gene and translates them into clear, practical insights—plus 3 personalized recommendations tailored to your genotype. ABCB1 (also known as MDR1) codes for P-glycoprotein (P-gp), a transport protein that helps move foreign compounds and pathogen-related molecules out of cells. A compelling takeaway: ABCB1 activity can influence both post-infection immune dynamics and medication effectiveness—meaning your genetics may help explain why certain treatments feel “too weak,” “too strong,” or inconsistent for you.

Personalized, Actionable Recommendations

Your results include personalized, DNA-based guidance designed to match how your ABCB1 (Chronic Lyme) genotype may influence detox transport activity and immune-related inflammation. You’ll receive dietary and supplement recommendations focused on supporting healthy immune function and recovery pathways. For example, your plan may highlight food strategies that support balanced inflammatory signaling (such as prioritizing omega-3-rich foods and polyphenol-rich plants) and supplement options commonly used to support immune regulation and cellular stress responses—selected and framed based on your genetic profile.

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: ABCB1 (sometimes called MDR1) provides instructions for making P-glycoprotein (P-gp), a transport protein that acts like a cellular bouncer. Its job is to move certain foreign compounds (including xenobiotics and pathogen-related molecules) out of cells. This transport function can shape how your body handles bacterial components after infections and can also affect how some medications are absorbed, distributed, and cleared.
: ABCB1 (Chronic Lyme) matters because genetic variants can change how active P-glycoprotein is. Research suggests that variants associated with reduced P-gp activity may be linked to a higher likelihood of persistent symptoms after a Borrelia burgdorferi infection (often referred to as chronic Lyme or PTLDS). Separately, ABCB1 variants can influence medication response—some people may require different dosing considerations or may not respond as expected to certain drugs because P-gp can alter how much medication reaches target tissues.
: Based on your ABCB1 (Chronic Lyme) results, you’ll receive 3 personalized recommendations with actionable next steps. These include dietary and supplement guidance tailored to your genotype, with a focus on supporting immune function, healthy inflammatory balance, and recovery resilience. Your recommendations may include targeted nutrition priorities (e.g., specific food patterns that support inflammatory signaling) and supplement suggestions aligned with your genetic profile and goals. This report is educational and can also help you have more informed conversations with your clinician—especially if you’re navigating persistent symptoms or medication effectiveness concerns.
: They may contribute to risk in some people. Studies have linked certain ABCB1 genetic variants—particularly those associated with reduced P-glycoprotein (P-gp) activity—to a higher likelihood of persistent symptoms after an acute Borrelia infection (often described as chronic Lyme or post-treatment Lyme disease syndrome, PTLDS). P-gp helps transport certain foreign or pathogen-related compounds out of cells, which may influence how the immune system is exposed to bacterial components and how inflammation is regulated over time. Genetics are only one piece of the puzzle, but knowing your ABCB1 profile can add personalized context to your immune and inflammation tendencies.
: This report can help explain why medication effects may differ from person to person. ABCB1 influences P-glycoprotein, which can affect how much of certain medications are absorbed and how much reaches specific tissues. Some ABCB1 genetic variants are associated with higher P-gp activity, which may reduce the effective concentration of certain drugs—potentially contributing to weaker response or the need for clinician-guided adjustments. While this report is not a prescription tool, it provides a genetics-informed layer of insight you can use to discuss treatment options, side effects, and response patterns with a qualified healthcare professional.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 5.00 out of 5 based on 8 customer ratings

5.0 (9 reviews)

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Yasmin B.

Rated 5 out of 5
I didn’t expect it to match my symptoms so closely, but it really did.
Maggie K.

Rated 5 out of 5
Seriously, I feel like this was made for what I needed right now.
Melody J.

Rated 5 out of 5
I have dealt with post tick flare ups for years, and the ABCB1 (Chronic Lyme) report was the first thing that connected my inflammation patterns with practical steps. It explained the gene piece in plain language, then gave a focused plan instead of a giant supplement list. I started prioritizing dietary antioxidants daily, and I discussed St. John’s Wort and Cat’s Claw with my clinician before trying them. Within a month my joint stiffness and brain fog were less frequent, and my labs looked calmer. The inflammation and autoimmunity framing made everything click.
Greg R.

Rated 5 out of 5
Achei incrível como o teste identificou detalhes que eu nem imaginava sobre minha saúde. As recomendações para antioxidantes me ajudaram bastante, já estou sentindo diferença!
Jill S.

Rated 5 out of 5
I brought my results to my naturopath and she immediately recognized the genetic markers relating to chronic inflammation. She actually recommended Cat’s Claw as well, so that gave me confidence the advice was solid. It really helped guide my supplement choices in a more personalized way.

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ABCB1 (Chronic Lyme)

Product features

Understanding Your ABCB1 (Chronic Lyme) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the ABCB1 (Chronic Lyme) gene do?

Why is the ABCB1 (Chronic Lyme) gene important?

What can I do based on my ABCB1 (Chronic Lyme) results?

Can ABCB1 genetic variants increase the risk of chronic Lyme symptoms?

What does an ABCB1 (Chronic Lyme) DNA test tell me about medication response?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers