What does the SCARB1 (Cardiovascular) gene do?

SCARB1 encodes a protein called scavenger receptor class B member 1 (SR-B1), which sits on cell membranes and acts as a receptor for HDL (“good cholesterol”). In simple terms, it helps the body handle cholesterol carried by HDL—supporting how cholesterol is transported and processed as part of a healthy lipid profile.

Why is the SCARB1 (Cardiovascular) gene important?

SCARB1 is important because genetic variants can influence how much SR-B1 protein is made or how it functions, which can affect HDL, LDL, triglycerides, and overall cholesterol balance. Research has linked certain SCARB1 variants with differences in risk for atherosclerosis and coronary heart disease, and some effects appear stronger under specific lifestyle conditions (for example, diets higher in saturated fat). Understanding your SCARB1 variants helps connect your biology to more targeted nutrition decisions.

What can I do based on my SCARB1 (Cardiovascular) results?

Your SCARB1 (Cardiovascular) results are paired with 4 personalized recommendations focused on dietary actions you can take. Depending on your genotype, your plan may include guidance on fat quality (e.g., saturated vs. unsaturated fats), food choices that support healthier HDL/LDL balance, and targeted nutrient strategies referenced in SCARB1 research. The goal is to turn your genetic insights into practical, day-to-day steps you can discuss with your healthcare professional—especially if you’re monitoring cholesterol markers or cardiovascular risk.

How do SCARB1 (Cardiovascular) variants affect cholesterol and heart disease risk?

SCARB1 (Cardiovascular) variants can influence lipid metabolism by changing SR-B1 levels or activity, which affects how HDL interacts with cells and how cholesterol is handled in the body. For example, research on rs5888 suggests the minor A allele has been associated with lower SCARB1 levels alongside higher HDL and lower triglycerides, and in some studies, a decreased risk of coronary heart disease or myocardial infarction. In contrast, rs4238001 has been associated with lower SCARB1 protein levels and increased coronary heart disease risk, with evidence that LDL may rise more in people eating diets high in saturated fat. Another variant, rs10846744, has been linked to atherosclerosis and coronary artery disease risk and to higher total cholesterol, LDL, and triglycerides in some studies—potentially via pathways related to inflammation and endothelial injury repair. This report helps you understand which patterns are most relevant to your genotype and what dietary actions may best support healthier markers.

What does SCARB1 (Cardiovascular) genetic testing include in this DNA report?

This SCARB1 (Cardiovascular) DNA report analyzes 3 SNPs in the SCARB1 gene (including widely researched variants such as rs5888, rs4238001, and rs10846744) and interprets them in the context of heart & blood vessel health. You’ll receive an easy-to-understand summary of what your genotype may imply for lipid profile tendencies (HDL, LDL, triglycerides) and cardiovascular risk signals seen in the research, plus 4 personalized dietary recommendations aligned to your results. The emphasis is on actionable nutrition guidance—so you can make more informed decisions about fat quality, dietary patterns, and nutrient strategies based on your genetics.

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SCARB1 (Cardiovascular)

Rated 4.83 out of 5 based on 6 customer ratings

4.8 (7 reviews)

SCARB1 (Cardiovascular)

Rated 4.83 out of 5 based on 6 customer ratings

4.8 (7 reviews)

The report provides up to 4 personalized recommendations based on 3 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Trusted by 200,000+ users & 2,000+ doctors

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Analyzes 3 Genetic Variants

Up to 4 DNA-Based, Science-Backed Recommendations

SCARB1 (Cardiovascular)

$59 $29

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Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your SCARB1 (Cardiovascular) Variants: A DNA Gene Report

Have you ever wondered why your cholesterol numbers don’t always respond the way you expect to diet changes? Do you want to understand how your body handles “good cholesterol” (HDL) and why heart risk can look different from one person to the next? Your SCARB1 (Cardiovascular) gene helps your cells interact with HDL, and knowing your SCARB1 variants can add a powerful layer of clarity to your heart & blood vessel health—so your next steps feel more personal, not generic.

Key Report Highlights

This SCARB1 (Cardiovascular) Gene Report analyzes 3 well-studied genetic variants (SNPs) in SCARB1 and delivers 4 personalized, dietary recommendations tailored to your genotype. SCARB1 encodes a receptor (SR-B1) that helps HDL deliver cholesterol where it needs to go—one reason it’s closely linked to lipid balance and cardiovascular outcomes. Compelling fact: certain SCARB1 variants have been associated with meaningful differences in HDL, LDL, and triglyceride levels, and in some cases, heart disease risk—especially in the context of dietary fat intake.

Personalized, Actionable Recommendations

Your results aren’t just “positive/negative”—they’re translated into personalized, DNA-based guidance. Based on your SCARB1 (Cardiovascular) genotype, the report provides 4 dietary recommendations designed to support healthier lipid patterns and cardiovascular function. For example, if your genetics suggest higher sensitivity to saturated fat–related LDL increases (as seen in research on specific SCARB1 variants), your plan may emphasize lowering saturated fat and choosing more unsaturated fats. If your profile suggests potential benefit from micronutrient strategies noted in the literature (such as vitamin A–related responses in certain genotypes), your recommendations may include food-first ways to optimize intake and discuss when supplementation might be worth reviewing with a clinician.

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: SCARB1 encodes a protein called scavenger receptor class B member 1 (SR-B1), which sits on cell membranes and acts as a receptor for HDL (“good cholesterol”). In simple terms, it helps the body handle cholesterol carried by HDL—supporting how cholesterol is transported and processed as part of a healthy lipid profile.
: SCARB1 is important because genetic variants can influence how much SR-B1 protein is made or how it functions, which can affect HDL, LDL, triglycerides, and overall cholesterol balance. Research has linked certain SCARB1 variants with differences in risk for atherosclerosis and coronary heart disease, and some effects appear stronger under specific lifestyle conditions (for example, diets higher in saturated fat). Understanding your SCARB1 variants helps connect your biology to more targeted nutrition decisions.
: Your SCARB1 (Cardiovascular) results are paired with 4 personalized recommendations focused on dietary actions you can take. Depending on your genotype, your plan may include guidance on fat quality (e.g., saturated vs. unsaturated fats), food choices that support healthier HDL/LDL balance, and targeted nutrient strategies referenced in SCARB1 research. The goal is to turn your genetic insights into practical, day-to-day steps you can discuss with your healthcare professional—especially if you’re monitoring cholesterol markers or cardiovascular risk.
: SCARB1 (Cardiovascular) variants can influence lipid metabolism by changing SR-B1 levels or activity, which affects how HDL interacts with cells and how cholesterol is handled in the body. For example, research on rs5888 suggests the minor A allele has been associated with lower SCARB1 levels alongside higher HDL and lower triglycerides, and in some studies, a decreased risk of coronary heart disease or myocardial infarction. In contrast, rs4238001 has been associated with lower SCARB1 protein levels and increased coronary heart disease risk, with evidence that LDL may rise more in people eating diets high in saturated fat. Another variant, rs10846744, has been linked to atherosclerosis and coronary artery disease risk and to higher total cholesterol, LDL, and triglycerides in some studies—potentially via pathways related to inflammation and endothelial injury repair. This report helps you understand which patterns are most relevant to your genotype and what dietary actions may best support healthier markers.
: This SCARB1 (Cardiovascular) DNA report analyzes 3 SNPs in the SCARB1 gene (including widely researched variants such as rs5888, rs4238001, and rs10846744) and interprets them in the context of heart & blood vessel health. You’ll receive an easy-to-understand summary of what your genotype may imply for lipid profile tendencies (HDL, LDL, triglycerides) and cardiovascular risk signals seen in the research, plus 4 personalized dietary recommendations aligned to your results. The emphasis is on actionable nutrition guidance—so you can make more informed decisions about fat quality, dietary patterns, and nutrient strategies based on your genetics.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.83 out of 5 based on 6 customer ratings

4.8 (7 reviews)

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Liam T.

Rated 4 out of 5
I’m 52 and have a family history of early heart disease, so I ordered SCARB1 (Cardiovascular) hoping for something actionable. The report explained why my cholesterol response to fats might be different, and it pushed me toward a Mediterranean Diet instead of just “eat healthy.” I started limiting saturated fat more strictly, cut out trans fats I was still getting from packaged snacks, and leaned into dietary oleic acid with olive oil and nuts. My only gripe is I wanted a quick one-page summary for busy days, the details are great but dense.
Sita K.

Rated 5 out of 5
After reading my results for scarb1, I started swapping out butter for olive oil and switched to a more Mediterranean-style diet. Added extra nuts and seeds too. My last cholesterol check was the best in years, so something is working! Super practical advice that fit into my routine.
Andrea M.

Rated 5 out of 5
Seeing my SCARB1 info made it clear what I needed to change. Now I’m actually eating more nuts and olive oil.
Greg W.

Rated 5 out of 5
I actually brought my results to my doctor and we talked about how I could use them to work on my cholesterol. Never thought I’d care about a gene before.
Trevor T.

Rated 5 out of 5
Oleic-rich swaps, calmer LDL.

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SCARB1 (Cardiovascular)

Product features

Understanding Your SCARB1 (Cardiovascular) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the SCARB1 (Cardiovascular) gene do?

Why is the SCARB1 (Cardiovascular) gene important?

What can I do based on my SCARB1 (Cardiovascular) results?

How do SCARB1 (Cardiovascular) variants affect cholesterol and heart disease risk?

What does SCARB1 (Cardiovascular) genetic testing include in this DNA report?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers