What does the NAF1 (Longevity & Heart Health) gene do?

NAF1 (Nuclear Assembly Factor 1) helps cells properly process genetic information so they can build and maintain key proteins. Importantly, it also plays a role in telomere maintenance by interacting with telomerase-related proteins (including TERT). Telomeres are protective caps on chromosomes that tend to shorten over time, so genes involved in telomere regulation can influence how cells age and recover from stress.

Why is the NAF1 (Longevity & Heart Health) gene important?

NAF1 is important because certain genetic variants have been associated with shorter telomeres and, in research, with higher likelihood of health issues involving the heart, blood vessels, and brain. The commonly studied variant rs7675998—particularly the “A” allele—has been linked to shorter telomeres and associations with high blood pressure, heart disease, stroke, and Alzheimer’s disease in published findings. While genetics don’t determine your destiny, understanding your NAF1 variants can clarify where you may benefit from more targeted prevention and lifestyle support.

How is the NAF1 gene linked to telomere length and longevity?

NAF1 supports cellular machinery involved in assembling and maintaining components that help regulate telomerase activity, including interactions with telomerase-related proteins such as TERT. Because telomerase helps maintain telomeres, variants in genes like NAF1 have been associated in studies with differences in telomere length. Shorter telomeres are often considered a marker of cellular aging and have been linked in research to cardiometabolic and neurodegenerative outcomes. This report helps you understand whether your NAF1 genetic variants suggest a tendency toward shorter telomeres and what personalized steps may support long-term heart and healthy-aging goals.

What can NAF1 genetic testing tell me about heart and brain health risks?

NAF1 genetic testing can highlight whether you carry variants that research has associated with telomere shortening and related health outcomes. The best-studied NAF1 variant (rs7675998) has been linked to shorter telomeres and associations with high blood pressure, heart disease, stroke, and Alzheimer’s disease in published evidence. Your report doesn’t diagnose disease, but it can help you personalize prevention—using DNA-informed dietary and supplement recommendations to support vascular function, healthy aging pathways, and risk-aware lifestyle choices.

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NAF1 (Longevity & Heart Health)

Rated 4.91 out of 5 based on 11 customer ratings

4.9 (12 reviews)

NAF1 (Longevity & Heart Health)

Rated 4.91 out of 5 based on 11 customer ratings

4.9 (12 reviews)

The report provides up to 5 personalized recommendations based on your genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Trusted by 200,000+ users & 2,000+ doctors

Proven track record: 3+ million analyses delivered

Analyzes Key Genetic Variants

Up to 5 DNA-Based, Science-Backed Recommendations

NAF1 (Longevity & Heart Health)

$59 $29

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Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your NAF1 (Longevity & Heart Health) Variants: A DNA Gene Report

Have you ever wondered why some people seem to stay healthier for longer—or why heart and blood vessel issues can run in families even when lifestyles look similar? What if part of the answer sits in your DNA, in a gene that helps regulate telomere length—one of the body’s key markers of cellular aging? Your NAF1 (Longevity & Heart Health) gene report helps you understand how your genetic variants may influence long-term cardiovascular resilience and healthy aging, so you can make more informed choices with a plan that fits you.

Key Report Highlights

This DNA report analyzes genetic variants in the NAF1 (Longevity & Heart Health) gene and translates your results into 5 personalized recommendations. NAF1 (Nuclear Assembly Factor 1) supports essential cellular processes and helps maintain telomere length by working with proteins involved in telomerase activity (including TERT). A compelling takeaway: NAF1-related differences have been linked in research to telomere shortening, which may connect to downstream risks in heart and brain health—making this gene a meaningful lens for understanding longevity-focused prevention.

Personalized, Actionable Recommendations

Your recommendations are tailored to your NAF1 (Longevity & Heart Health) genotype, turning genetic insights into practical next steps. You’ll receive dietary and supplement recommendations designed to support cardiovascular function and healthy aging pathways associated with telomere biology. For example, your plan may include food-pattern guidance that emphasizes heart-supportive nutrients and inflammation-aware choices, plus supplement suggestions aligned with your genetics and goals (such as targeted support for vascular health and antioxidant defenses).

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: NAF1 (Nuclear Assembly Factor 1) helps cells properly process genetic information so they can build and maintain key proteins. Importantly, it also plays a role in telomere maintenance by interacting with telomerase-related proteins (including TERT). Telomeres are protective caps on chromosomes that tend to shorten over time, so genes involved in telomere regulation can influence how cells age and recover from stress.
: NAF1 is important because certain genetic variants have been associated with shorter telomeres and, in research, with higher likelihood of health issues involving the heart, blood vessels, and brain. The commonly studied variant rs7675998—particularly the “A” allele—has been linked to shorter telomeres and associations with high blood pressure, heart disease, stroke, and Alzheimer’s disease in published findings. While genetics don’t determine your destiny, understanding your NAF1 variants can clarify where you may benefit from more targeted prevention and lifestyle support.
: Based on your NAF1 (Longevity & Heart Health) results, you’ll receive 5 personalized recommendations that translate your genotype into actionable guidance. These include dietary and supplement recommendations to help support cardiovascular function and healthy aging strategies connected to telomere biology. Your plan is designed to be practical—helping you prioritize what to focus on, what to monitor over time, and which supportive habits may be most relevant for your genetic profile.
: NAF1 supports cellular machinery involved in assembling and maintaining components that help regulate telomerase activity, including interactions with telomerase-related proteins such as TERT. Because telomerase helps maintain telomeres, variants in genes like NAF1 have been associated in studies with differences in telomere length. Shorter telomeres are often considered a marker of cellular aging and have been linked in research to cardiometabolic and neurodegenerative outcomes. This report helps you understand whether your NAF1 genetic variants suggest a tendency toward shorter telomeres and what personalized steps may support long-term heart and healthy-aging goals.
: NAF1 genetic testing can highlight whether you carry variants that research has associated with telomere shortening and related health outcomes. The best-studied NAF1 variant (rs7675998) has been linked to shorter telomeres and associations with high blood pressure, heart disease, stroke, and Alzheimer’s disease in published evidence. Your report doesn’t diagnose disease, but it can help you personalize prevention—using DNA-informed dietary and supplement recommendations to support vascular function, healthy aging pathways, and risk-aware lifestyle choices.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.91 out of 5 based on 11 customer ratings

4.9 (12 reviews)

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Hassan U.

Rated 5 out of 5
Just what I needed for my heart, definitely sharing this with my dad too.
Arjun Z.

Rated 5 out of 5
Somehow this nailed exactly what I needed to hear about my heart health.
Elijah W.

Rated 5 out of 5
Polyphenols plan, calmer pulse.
Luca M.

Rated 5 out of 5
Wasn’t planning to review but wow, this was helpful. Honestly didn’t expect to actually change my diet but here I am eating more polyphenols!
Zara P.

Rated 4 out of 5
I got the NAF1 (Longevity & Heart Health) report because heart disease runs in my family and I wanted something more structured than generic “eat better” advice. The recommendations were practical, especially the focus on dietary polyphenols, dietary antioxidants, and limiting trans fats. It also helped me commit to omega-3 fish oil consistently instead of randomly. I’m giving 4 stars because I would have liked clearer guidance on how to prioritize the actions, plus a brief section on what to recheck with labs over time. Still, it felt actionable.

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NAF1 (Longevity & Heart Health)

Product features

Understanding Your NAF1 (Longevity & Heart Health) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the NAF1 (Longevity & Heart Health) gene do?

Why is the NAF1 (Longevity & Heart Health) gene important?

What can I do based on my NAF1 (Longevity & Heart Health) results?

How is the NAF1 gene linked to telomere length and longevity?

What can NAF1 genetic testing tell me about heart and brain health risks?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers