What does the CYP4F2 (Blood Pressure) gene do?

CYP4F2 is an enzyme in the cytochrome P450 family that helps process (metabolize) fatty acids and inflammatory signaling molecules. One of its key roles is converting arachidonic acid into 20-HETE, a compound that can affect how strongly blood vessels constrict. It also helps inactivate leukotriene B4, an inflammatory mediator. Together, these functions connect CYP4F2 to vascular tone and inflammation—two important factors in blood pressure regulation.

Why is the CYP4F2 (Blood Pressure) gene important?

CYP4F2 is important because genetic variants can change how much of the CYP4F2 enzyme you produce or how it functions, which may alter 20-HETE signaling and related blood vessel responses. Several CYP4F2 variants have been associated with increased risk of hypertension, and research suggests certain variants (such as rs2108622) may also relate to ischemic stroke risk in some populations. These same variants may help explain why some people see less blood pressure improvement from common interventions like weight loss or omega-3 intake.

What can I do based on my CYP4F2 (Blood Pressure) results?

Based on your CYP4F2 (Blood Pressure) results, you’ll receive 2 personalized recommendations focused on dietary and supplement actions. Your report translates your genotype into practical guidance—such as how to approach omega-3 intake if your variant is linked to a different blood pressure response, and which supplement strategies may best align with pathways related to vascular tone and inflammation. The goal is to help you make more targeted, evidence-informed choices rather than relying on trial and error.

Can CYP4F2 gene variants increase the risk of high blood pressure (hypertension)?

Yes. Multiple CYP4F2 variants have been associated in research with higher hypertension risk. For example, rs2108622 (V433M) has been linked to increased risk of hypertension (notably in men in some studies) and has also been studied in relation to ischemic stroke. Other variants such as rs3093100 have been associated with altered CYP4F2 expression and changes in urinary 20-HETE levels, which may relate to blood pressure regulation. This report analyzes key CYP4F2 SNPs to help you understand whether your genetics may be contributing to your blood pressure tendencies.

What do I learn from CYP4F2 (Blood Pressure) genetic testing in a DNA report?

A CYP4F2 (Blood Pressure) DNA report shows which versions of specific CYP4F2 variants you carry and explains what those variants may imply for blood pressure-related biology, including pathways involving 20-HETE and inflammatory mediators. Instead of providing generic tips, the report uses your genotype to generate personalized dietary and supplement recommendations—helping you focus on strategies that better match how your body may process fatty acids and regulate vascular tone.

Save $30

CYP4F2 (Blood Pressure)

Rated 4.75 out of 5 based on 4 customer ratings

4.8 (5 reviews)

CYP4F2 (Blood Pressure)

Rated 4.75 out of 5 based on 4 customer ratings

4.8 (5 reviews)

The report provides up to 2 personalized recommendations based on 3 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

$59

$29

Save $30

Add to cart Added

Trusted by 200,000+ users & 2,000+ doctors

Proven track record: 3+ million analyses delivered

Analyzes 3 Genetic Variants

Up to 2 DNA-Based, Science-Backed Recommendations

CYP4F2 (Blood Pressure)

$59 $29

Add to cart Added

Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your CYP4F2 (Blood Pressure) Variants: A DNA Gene Report

Ever wonder why your blood pressure trends higher than you’d expect—even when you’re trying to eat well and stay active? Do you respond differently to omega-3s, weight loss, or other heart-healthy habits than friends or family? Your CYP4F2 (Blood Pressure) gene helps regulate inflammatory signaling and blood vessel tone, and understanding your personal CYP4F2 variants can reveal genetic factors that may influence your risk for hypertension—so you can make choices that fit your biology.

Key Report Highlights

This CYP4F2 (Blood Pressure) Gene Report analyzes 3 research-backed genetic variants (SNPs) linked to blood pressure regulation and hypertension risk, and delivers 2 personalized recommendations tailored to your genotype. CYP4F2 is part of the cytochrome P450 enzyme family and plays a key role in metabolizing fatty acids and inflammatory molecules, including converting arachidonic acid into 20-HETE—a potent signaling molecule that can promote blood vessel constriction. Because 20-HETE can influence vascular tone, your CYP4F2 genetics may help explain differences in blood pressure tendencies and response to common lifestyle strategies.

Personalized, Actionable Recommendations

Your results include DNA-based guidance designed around how your specific CYP4F2 (Blood Pressure) genotype may affect blood pressure-related pathways. You’ll receive 2 personalized recommendations across dietary and supplement categories, with practical, step-by-step suggestions. For example, your report may highlight how certain carriers of the rs2108622 (V433M) variant can respond differently to omega-3 fatty acids for blood pressure support, or it may provide targeted supplement guidance aligned with inflammation and vascular function—so you can prioritize strategies that are more likely to be effective for you.

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: CYP4F2 is an enzyme in the cytochrome P450 family that helps process (metabolize) fatty acids and inflammatory signaling molecules. One of its key roles is converting arachidonic acid into 20-HETE, a compound that can affect how strongly blood vessels constrict. It also helps inactivate leukotriene B4, an inflammatory mediator. Together, these functions connect CYP4F2 to vascular tone and inflammation—two important factors in blood pressure regulation.
: CYP4F2 is important because genetic variants can change how much of the CYP4F2 enzyme you produce or how it functions, which may alter 20-HETE signaling and related blood vessel responses. Several CYP4F2 variants have been associated with increased risk of hypertension, and research suggests certain variants (such as rs2108622) may also relate to ischemic stroke risk in some populations. These same variants may help explain why some people see less blood pressure improvement from common interventions like weight loss or omega-3 intake.
: Based on your CYP4F2 (Blood Pressure) results, you’ll receive 2 personalized recommendations focused on dietary and supplement actions. Your report translates your genotype into practical guidance—such as how to approach omega-3 intake if your variant is linked to a different blood pressure response, and which supplement strategies may best align with pathways related to vascular tone and inflammation. The goal is to help you make more targeted, evidence-informed choices rather than relying on trial and error.
: Yes. Multiple CYP4F2 variants have been associated in research with higher hypertension risk. For example, rs2108622 (V433M) has been linked to increased risk of hypertension (notably in men in some studies) and has also been studied in relation to ischemic stroke. Other variants such as rs3093100 have been associated with altered CYP4F2 expression and changes in urinary 20-HETE levels, which may relate to blood pressure regulation. This report analyzes key CYP4F2 SNPs to help you understand whether your genetics may be contributing to your blood pressure tendencies.
: A CYP4F2 (Blood Pressure) DNA report shows which versions of specific CYP4F2 variants you carry and explains what those variants may imply for blood pressure-related biology, including pathways involving 20-HETE and inflammatory mediators. Instead of providing generic tips, the report uses your genotype to generate personalized dietary and supplement recommendations—helping you focus on strategies that better match how your body may process fatty acids and regulate vascular tone.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.75 out of 5 based on 4 customer ratings

4.8 (5 reviews)

Share your thoughts

If you've used this product, share your thoughts with other customers

Only customers who purchased this product can leave reviews

Liam T.

Rated 5 out of 5
Salt cut, pressure finally behaved
Felipe J.

Rated 5 out of 5
Based on what I learned, I started cutting back on salty snacks and added a vitamin K1 supplement to my routine. My recent blood pressure readings are a little better already. This gave me actions to take, not just information.
Yuna Z.

Rated 5 out of 5
I was pretty skeptical about DNA health things, but this actually gave me advice that made sense for me. I liked how it explained salt sensitivity and why vitamin K1 could help. Didn’t expect to get anything tangible out of it but I did, so I’m glad I tried.
Iris A.

Rated 4 out of 5
I ordered the cyp4f2 (blood pressure) report after my dad had a hypertension scare, and I wanted something more concrete than generic “eat better” advice. The explanation of how this gene can affect vitamin K handling was easy to follow, and the action list was practical. I started a small vitamin K1 supplement and got serious about limiting salt, especially in sauces and packaged snacks. My home readings look steadier after a few weeks. I am giving 4 stars because I wanted a clearer note on how often to retest blood pressure and what to discuss with a clinician.
Luz L.

Rated 5 out of 5
I never realized my blood pressure could be affected by my genes. This made me look at my diet differently.

CYP4F2 (Blood Pressure)

Product features

Understanding Your CYP4F2 (Blood Pressure) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the CYP4F2 (Blood Pressure) gene do?

Why is the CYP4F2 (Blood Pressure) gene important?

What can I do based on my CYP4F2 (Blood Pressure) results?

Can CYP4F2 gene variants increase the risk of high blood pressure (hypertension)?

What do I learn from CYP4F2 (Blood Pressure) genetic testing in a DNA report?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers