What does the CYP4A11 (Blood Pressure) gene do?

CYP4A11 is a gene that codes for an enzyme in the cytochrome P450 family. In simple terms, it helps your body process certain fatty acids—especially arachidonic acid—into signaling molecules. One of the most important products is 20-HETE, which can affect how tightly blood vessels constrict. Because vessel constriction is a key factor in blood pressure, CYP4A11 plays a meaningful role in cardiovascular regulation.

Why is the CYP4A11 (Blood Pressure) gene important?

CYP4A11 is important because certain genetic variants can change how well the enzyme works, which may alter 20-HETE signaling and, in turn, influence blood vessel tone and blood pressure risk. Research has linked specific variants (including well-studied changes such as rs1126742 and variants often inherited alongside it) with increased odds of hypertension in multiple populations. Some evidence also suggests the risk impact may be stronger in people exposed to additional triggers, such as high-salt diets or smoking, and certain variants have been associated with kidney-related complications in hypertensive individuals.

What can I do based on my CYP4A11 (Blood Pressure) results?

Based on your CYP4A11 (Blood Pressure) results, you’ll receive 4 personalized recommendations that focus on actionable dietary and supplement guidance. These recommendations are tailored to your genotype and may include steps such as optimizing sodium intake, emphasizing dietary patterns that support vascular function, and targeted supplement options aligned with blood pressure support. Your report is designed to help you prioritize what’s most relevant for your genetics rather than relying on one-size-fits-all advice.

Which CYP4A11 variants are associated with hypertension risk?

Multiple CYP4A11 variants have been associated with hypertension risk in genetic studies. The best-characterized is rs1126742 (often referenced as T8590C), where the minor allele has been linked to reduced enzyme catalytic activity and a higher risk of hypertension across several groups. Additional variants reported in the literature include rs4660980 (often inherited alongside rs1126742), rs3890011, rs9332982, and rs9333025, which have been associated with hypertension and, in some studies, progression of kidney disease in hypertensive individuals. This report analyzes 5 SNPs to provide a consolidated, personalized interpretation of your CYP4A11-related risk signals.

What do I get from a CYP4A11 (Blood Pressure) genetic test report?

A CYP4A11 (Blood Pressure) genetic test report goes beyond raw DNA data by translating your genotype into health-relevant insights. You receive analysis of 5 CYP4A11 variants linked to blood pressure regulation and vascular signaling, plus 4 personalized recommendations focused on dietary and supplement strategies. The goal is to highlight how your genetics may influence blood vessel constriction pathways (including arachidonic acid metabolism and 20-HETE signaling) and to provide practical, individualized actions you can discuss with your healthcare provider and apply to your daily routine.

Save $30

CYP4A11 (Blood Pressure)

Rated 4.75 out of 5 based on 4 customer ratings

4.8 (5 reviews)

CYP4A11 (Blood Pressure)

Rated 4.75 out of 5 based on 4 customer ratings

4.8 (5 reviews)

The report provides up to 4 personalized recommendations based on 5 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

$59

$29

Save $30

Add to cart Added

Trusted by 200,000+ users & 2,000+ doctors

Proven track record: 3+ million analyses delivered

Analyzes 5 Genetic Variants

Up to 4 DNA-Based, Science-Backed Recommendations

CYP4A11 (Blood Pressure)

$59 $29

Add to cart Added

Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your CYP4A11 (Blood Pressure) Variants: A DNA Gene Report

Do you ever wonder why your blood pressure seems sensitive to salt, stress, or lifestyle changes that don’t affect other people the same way? Are you curious whether your body tends to produce stronger “blood vessel tightening” signals—making it harder to keep numbers in a healthy range? The CYP4A11 (Blood Pressure) gene helps regulate how your body processes certain fats into signaling molecules that influence vessel tone, so understanding your CYP4A11 variants can reveal a personal genetic layer behind hypertension risk and guide more targeted next steps.

Key Report Highlights

This CYP4A11 (Blood Pressure) DNA report analyzes 5 key genetic variants (SNPs) linked to blood pressure and vascular function and delivers 4 personalized recommendations tailored to your genotype. CYP4A11 encodes a cytochrome P450 enzyme that metabolizes arachidonic acid into 20-HETE—an important signaling molecule known to promote blood vessel constriction. A compelling takeaway: changes in CYP4A11 activity can shift 20-HETE signaling, which may influence how strongly your blood vessels constrict and how your body responds to common blood pressure triggers like high salt intake or smoking.

Personalized, Actionable Recommendations

Your results translate into 4 personalized, DNA-based recommendations designed around how your CYP4A11 (Blood Pressure) genotype may influence blood pressure regulation. Recommendations focus on practical dietary and supplement strategies, prioritized to match your variant pattern and risk signals. For example, your plan may include guidance to tighten sodium targets and emphasize potassium-rich whole foods if your variants are associated with higher salt sensitivity, along with supplement considerations that support vascular health and healthy blood pressure signaling (when appropriate for your profile).

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: CYP4A11 is a gene that codes for an enzyme in the cytochrome P450 family. In simple terms, it helps your body process certain fatty acids—especially arachidonic acid—into signaling molecules. One of the most important products is 20-HETE, which can affect how tightly blood vessels constrict. Because vessel constriction is a key factor in blood pressure, CYP4A11 plays a meaningful role in cardiovascular regulation.
: CYP4A11 is important because certain genetic variants can change how well the enzyme works, which may alter 20-HETE signaling and, in turn, influence blood vessel tone and blood pressure risk. Research has linked specific variants (including well-studied changes such as rs1126742 and variants often inherited alongside it) with increased odds of hypertension in multiple populations. Some evidence also suggests the risk impact may be stronger in people exposed to additional triggers, such as high-salt diets or smoking, and certain variants have been associated with kidney-related complications in hypertensive individuals.
: Based on your CYP4A11 (Blood Pressure) results, you’ll receive 4 personalized recommendations that focus on actionable dietary and supplement guidance. These recommendations are tailored to your genotype and may include steps such as optimizing sodium intake, emphasizing dietary patterns that support vascular function, and targeted supplement options aligned with blood pressure support. Your report is designed to help you prioritize what’s most relevant for your genetics rather than relying on one-size-fits-all advice.
: Multiple CYP4A11 variants have been associated with hypertension risk in genetic studies. The best-characterized is rs1126742 (often referenced as T8590C), where the minor allele has been linked to reduced enzyme catalytic activity and a higher risk of hypertension across several groups. Additional variants reported in the literature include rs4660980 (often inherited alongside rs1126742), rs3890011, rs9332982, and rs9333025, which have been associated with hypertension and, in some studies, progression of kidney disease in hypertensive individuals. This report analyzes 5 SNPs to provide a consolidated, personalized interpretation of your CYP4A11-related risk signals.
: A CYP4A11 (Blood Pressure) genetic test report goes beyond raw DNA data by translating your genotype into health-relevant insights. You receive analysis of 5 CYP4A11 variants linked to blood pressure regulation and vascular signaling, plus 4 personalized recommendations focused on dietary and supplement strategies. The goal is to highlight how your genetics may influence blood vessel constriction pathways (including arachidonic acid metabolism and 20-HETE signaling) and to provide practical, individualized actions you can discuss with your healthcare provider and apply to your daily routine.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.75 out of 5 based on 4 customer ratings

4.8 (5 reviews)

Share your thoughts

If you've used this product, share your thoughts with other customers

Only customers who purchased this product can leave reviews

Blake Z.

Rated 5 out of 5
Always intrigued by the genetics behind blood pressure regulation, so seeing my CYP4A11 variant analyzed alongside dietary nitrate and ACE pathways was fascinating. The integration of genetics with practical nutrition, like hibiscus supplementation, really showed thoughtful curation. I wish more products explained the mechanisms as clearly as this did. It’s actually helped me understand what to try changing in my diet.
Nadia L.

Rated 5 out of 5
Did not expect to learn so much about how my genes could affect blood pressure. I actually shared some of these tips with my sister.
Alessia T.

Rated 4 out of 5
Ho preso il report CYP4A11 (Blood Pressure) perché in famiglia l’ipertensione è una costante e volevo capire se avevo margini di prevenzione. Mi è piaciuto che non si limita a dire “mangia meglio”, ma propone azioni concrete, come limitare il sale e usare ACE inibitori naturali nella dieta. Interessante anche il consiglio sull’ibisco e sui nitrati alimentari, ho iniziato con barbabietola e rucola. Do 4 stelle perché avrei gradito esempi di porzioni giornaliere e qualche avvertenza in più sulle interazioni con farmaci.
Dennis P.

Rated 5 out of 5
I’ve read plenty of health blogs but this gave me info I couldn’t just Google, especially personalized advice about salt and natural ACE inhibitors. It felt actionable, not generic, and I really appreciated having actual recommendations rather than just vague warnings or generic tips.
Reiko J.

Rated 5 out of 5
Totally spot-on.

CYP4A11 (Blood Pressure)

Product features

Understanding Your CYP4A11 (Blood Pressure) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the CYP4A11 (Blood Pressure) gene do?

Why is the CYP4A11 (Blood Pressure) gene important?

What can I do based on my CYP4A11 (Blood Pressure) results?

Which CYP4A11 variants are associated with hypertension risk?

What do I get from a CYP4A11 (Blood Pressure) genetic test report?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers