What does the AGT (Cardiovascular & Fitness) gene do?

The AGT gene provides instructions for making angiotensinogen, a protein that starts the renin-angiotensin system (RAS). RAS is one of the body’s main tools for regulating blood pressure and fluid balance. Through a chain of steps, angiotensinogen can be converted into angiotensin II, which can narrow blood vessels and signal hormones (like aldosterone) that influence how the kidneys retain salt and water—factors that can raise blood volume and blood pressure.

Why is the AGT (Cardiovascular & Fitness) gene important?

AGT is important because genetic variants can influence how much angiotensinogen your body produces and how strongly the RAS pathway may affect your blood vessels and fluid balance. Certain AGT variants (commonly discussed in research as rs699/M235T) have been associated with higher risk of conditions related to blood pressure and circulation, including hypertension and coronary heart disease, and may also relate to how much your blood pressure improves with exercise. Interestingly, some research also links these variants to stronger performance in power-focused sports—highlighting how the same biology can have different implications depending on your goals and health context.

What can I do based on my AGT (Cardiovascular & Fitness) results?

Based on your AGT results, you’ll receive 11 personalized recommendations spanning dietary, lifestyle, and supplement categories. These can include tailored guidance to support healthy blood pressure regulation (such as nutrition strategies that prioritize heart-healthy patterns and electrolyte balance), exercise and training considerations (including how to structure activity for cardiovascular benefit), and optional supplement considerations when appropriate. The goal is to give you clear, genetics-informed actions you can implement and monitor over time.

How does the AGT gene affect blood pressure and hypertension risk?

AGT influences blood pressure through its role in the renin-angiotensin system (RAS). Angiotensinogen (made from AGT) can be converted into angiotensin II, which constricts blood vessels and can increase aldosterone signaling. Aldosterone affects how the kidneys handle sodium, potassium, and water—shifting fluid balance in ways that can raise blood volume and blood pressure. Certain AGT genetic variants have been associated in research with increased hypertension risk and related cardiovascular outcomes. A DNA-based AGT report helps you understand whether your genetics may tilt this system toward higher pressure, and provides personalized steps to support healthier regulation.

What can an AGT (Cardiovascular & Fitness) genetic test tell me about exercise response and performance?

An AGT-focused genetic analysis can provide insight into how your cardiovascular system may respond to training—particularly blood pressure changes with exercise. Some AGT variants have been associated with a weaker blood-pressure-lowering response to exercise in certain individuals, which may influence how you track progress and which training and recovery strategies you prioritize. At the same time, research has also linked some variants with advantages in power-oriented performance. This report connects your AGT genetic variants to practical, personalized recommendations so you can train smarter while supporting long-term heart and blood vessel health.

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AGT (Cardiovascular & Fitness)

Rated 4.67 out of 5 based on 12 customer ratings

4.7 (13 reviews)

AGT (Cardiovascular & Fitness)

Rated 4.67 out of 5 based on 12 customer ratings

4.7 (13 reviews)

The report provides up to 11 personalized recommendations based on your genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Analyzes Key Genetic Variants

Up to 11 DNA-Based, Science-Backed Recommendations

AGT (Cardiovascular & Fitness)

$59 $29

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Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your AGT (Cardiovascular & Fitness) Variants: A DNA Gene Report

Have you ever wondered why your blood pressure seems to run high despite “doing the right things,” or why exercise doesn’t always move the needle the way you expect? Are you curious whether your genetics might influence how your blood vessels respond under stress—or even how naturally suited you are for power-focused performance? The AGT (Cardiovascular & Fitness) Gene Report helps you understand how your AGT genetic variants may shape blood pressure regulation and fitness traits, so you can make more informed choices for your heart, circulation, and training.

Key Report Highlights

This report analyzes key genetic variants in the AGT (Cardiovascular & Fitness) gene and translates your results into 11 personalized recommendations. AGT provides instructions for making angiotensinogen—an essential starting point in the renin-angiotensin system (RAS), a pathway the body uses to raise blood pressure when it’s low by tightening blood vessels and influencing fluid and salt balance. A compelling takeaway: changes in this pathway can affect both cardiovascular risk factors (like higher blood pressure) and, in some cases, traits linked to power performance.

Personalized, Actionable Recommendations

Your recommendations are personalized to your AGT (Cardiovascular & Fitness) genotype, turning genetic insights into practical next steps across dietary, lifestyle, and supplement guidance. For example, your plan may include strategies to support healthy blood pressure through sodium/potassium balance and hydration habits, as well as training guidance to optimize cardiovascular response and recovery. Where appropriate, the report may also highlight supplement considerations that align with your genetics and goals—always designed to be actionable and easy to discuss with a clinician or coach.

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: The AGT gene provides instructions for making angiotensinogen, a protein that starts the renin-angiotensin system (RAS). RAS is one of the body’s main tools for regulating blood pressure and fluid balance. Through a chain of steps, angiotensinogen can be converted into angiotensin II, which can narrow blood vessels and signal hormones (like aldosterone) that influence how the kidneys retain salt and water—factors that can raise blood volume and blood pressure.
: AGT is important because genetic variants can influence how much angiotensinogen your body produces and how strongly the RAS pathway may affect your blood vessels and fluid balance. Certain AGT variants (commonly discussed in research as rs699/M235T) have been associated with higher risk of conditions related to blood pressure and circulation, including hypertension and coronary heart disease, and may also relate to how much your blood pressure improves with exercise. Interestingly, some research also links these variants to stronger performance in power-focused sports—highlighting how the same biology can have different implications depending on your goals and health context.
: Based on your AGT results, you’ll receive 11 personalized recommendations spanning dietary, lifestyle, and supplement categories. These can include tailored guidance to support healthy blood pressure regulation (such as nutrition strategies that prioritize heart-healthy patterns and electrolyte balance), exercise and training considerations (including how to structure activity for cardiovascular benefit), and optional supplement considerations when appropriate. The goal is to give you clear, genetics-informed actions you can implement and monitor over time.
: AGT influences blood pressure through its role in the renin-angiotensin system (RAS). Angiotensinogen (made from AGT) can be converted into angiotensin II, which constricts blood vessels and can increase aldosterone signaling. Aldosterone affects how the kidneys handle sodium, potassium, and water—shifting fluid balance in ways that can raise blood volume and blood pressure. Certain AGT genetic variants have been associated in research with increased hypertension risk and related cardiovascular outcomes. A DNA-based AGT report helps you understand whether your genetics may tilt this system toward higher pressure, and provides personalized steps to support healthier regulation.
: An AGT-focused genetic analysis can provide insight into how your cardiovascular system may respond to training—particularly blood pressure changes with exercise. Some AGT variants have been associated with a weaker blood-pressure-lowering response to exercise in certain individuals, which may influence how you track progress and which training and recovery strategies you prioritize. At the same time, research has also linked some variants with advantages in power-oriented performance. This report connects your AGT genetic variants to practical, personalized recommendations so you can train smarter while supporting long-term heart and blood vessel health.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.67 out of 5 based on 12 customer ratings

4.7 (13 reviews)

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Brian H.

Rated 5 out of 5
Hibiscus calmed my BP.
Hiroshi R.

Rated 5 out of 5
AGT（Cardiovascular & Fitness）を読んで、自分が血管の収縮や血圧に影響しやすいタイプかもと理解できました。家族に高血圧が多く、検診前はいつも不安でしたが、遺伝傾向と生活でできることが整理されて安心感が増えました。提案されていたマグネシウムグリシネートを夜に取り入れ、日中はハイビスカスティーを飲むように変更。さらに塩分を意識して外食の選び方も調整しました。運動面も、無理に追い込むより継続を優先する方針にでき、心拍の上がり方が安定してきました。
Darius S.

Rated 4 out of 5
the AGT report helped me focus on salt limits and omega-3, but the supplement dosing ranges could be clearer.

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AGT (Cardiovascular & Fitness)

Product features

Understanding Your AGT (Cardiovascular & Fitness) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the AGT (Cardiovascular & Fitness) gene do?

Why is the AGT (Cardiovascular & Fitness) gene important?

What can I do based on my AGT (Cardiovascular & Fitness) results?

How does the AGT gene affect blood pressure and hypertension risk?

What can an AGT (Cardiovascular & Fitness) genetic test tell me about exercise response and performance?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers