What does the UGT (Detox) gene do?

UGT (UDP-glucuronosyltransferase) refers to a family of enzymes that perform glucuronidation—a process that helps make various compounds more water-soluble so your body can eliminate them more efficiently. UGT activity supports the clearance of normal waste products (like bilirubin from red blood cell breakdown), certain hormones, environmental chemicals (including BPA-related compounds), and many medications. UGT function is also connected to antioxidant defense because these pathways interact with glutathione-related protection against oxidative stress.

Why is the UGT (Detox) gene important?

UGT (Detox) genes are important because genetic variants can change how efficiently UGT enzymes work. Lower-activity variants—especially in UGT1A1 (such as UGT1A1*28, and other reduced-function alleles reported in research)—may reduce detox capacity and contribute to higher bilirubin levels or increased sensitivity to certain drugs and chemicals. Other UGT variants can influence oxidative stress balance (through glutathione-related mechanisms) and may affect how you respond to specific exposures, including medications. Knowing your variants helps you understand your personal detox “speed,” potential sensitivities, and where supportive strategies may be most beneficial.

What can I do based on my UGT (Detox) results?

Based on your UGT (Detox) results, you’ll receive 5 personalized recommendations that translate your genetics into practical next steps. These include dietary recommendations (foods and patterns that support detox and antioxidant defenses), lifestyle recommendations (ways to reduce avoidable chemical load and support healthy clearance), and supplement recommendations (when appropriate, targeted options aligned with your genotype). The goal is to help you make informed, actionable choices that match your body’s detox capacity—especially around medication considerations, environmental exposures, and oxidative stress support.

Can UGT1A1 variants affect bilirubin levels and detoxification?

Yes. UGT1A1 plays a central role in processing bilirubin, a normal waste product created when red blood cells are broken down. Research shows that certain UGT1A1 variants are associated with reduced enzyme activity, which can slow bilirubin clearance and contribute to higher bilirubin levels in some people. These same reduced-function variants may also indicate slower glucuronidation for other compounds, which can influence overall detox efficiency and sensitivity to specific drugs or environmental chemicals. A DNA-based UGT report helps identify whether you carry variants linked to lower activity and provides personalized strategies to support healthy detox pathways.

What can a UGT (Detox) genetic test tell me about medication and chemical sensitivity?

A UGT (Detox) genetic test can highlight variants that may change how quickly you glucuronidate (process) certain medications and chemicals. Because UGT enzymes are involved in metabolizing a meaningful portion of drugs and in clearing compounds like BPA-related chemicals and steroid hormones, variants in genes such as UGT1A1, UGT1A6, and UGT2B7 can help explain why some people experience stronger effects, side effects, or reduced effectiveness with certain substances. This report analyzes 11 SNPs and converts your results into 5 personalized dietary, lifestyle, and supplement recommendations—so you can make more informed choices and have better-context conversations with your healthcare provider, especially when medications are involved.

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UGT (Detox)

Rated 4.77 out of 5 based on 13 customer ratings

4.8 (14 reviews)

UGT (Detox)

Rated 4.77 out of 5 based on 13 customer ratings

4.8 (14 reviews)

The report provides up to 5 personalized recommendations based on over 11 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

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Trusted by 200,000+ users & 2,000+ doctors

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Analyzes 11 Genetic Variants

Up to 5 DNA-Based, Science-Backed Recommendations

UGT (Detox)

$59 $29

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Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your UGT (Detox) Variants: A DNA Gene Report

Do you ever feel unusually sensitive to certain medications, alcohol, or everyday chemicals like plastics? Have you noticed yellowing of the eyes/skin, stubborn fatigue, or that you “don’t bounce back” the way others do after exposure to stressors? Your UGT (Detox) genes help run one of the body’s key clearance pathways—so understanding your personal UGT variants can explain why detox demands may feel higher for you and what to do about it.

Key Report Highlights

This UGT (Detox) Gene Report analyzes 11 genetic variants (SNPs) across UGT-related genes and translates your results into 5 personalized recommendations tailored to your genotype. UGT enzymes drive glucuronidation—an essential detox step that helps your body process and eliminate substances such as bilirubin (a normal waste product), steroid hormones, BPA-related chemicals, and even an estimated ~15% of FDA‑approved medications. A compelling insight: common UGT1A1 variants (such as UGT1A1*28) have been reported to reduce UGT enzyme activity substantially, which can contribute to slower clearance and higher sensitivity to certain exposures.

Personalized, Actionable Recommendations

Your recommendations are generated from your specific UGT (Detox) genotype—so the guidance is personalized rather than one-size-fits-all. You’ll receive a mix of dietary, lifestyle, and supplement recommendations designed to support detox pathways and oxidative stress defenses linked to UGT function and glutathione biology. For example, your report may suggest targeted food strategies that support healthy glucuronidation and antioxidant status (e.g., emphasizing specific phytonutrient-rich foods), and lifestyle guidance to reduce avoidable chemical load (e.g., practical steps to limit BPA/plastic exposures). When appropriate, it may also include supplement considerations that align with your genetic detox capacity and overall goals.

User-Friendly Format and Trust

With actionable and easy-to-understand recommendations, the report is designed for seamless integration into your daily life. Its user-friendly format ensures accessibility, making complex genetic data understandable and practical for users at all levels of familiarity with genetic information.

The report is rooted in accuracy and reliability, backed by comprehensive scientific research from reputable sources. It has garnered the trust of over 150,000 users and 1,000+ healthcare professionals. Furthermore, the report complies with HIPAA and GDPR, ensuring your privacy and security are prioritized.

Getting Started

To embark on this journey, simply purchase a DNA kit for an easy at-home sample collection, guaranteeing a hassle-free process. Delve into a personalized approach to wellness and equip yourself with actionable insights to enrich your life and health.

Product FAQs

: UGT (UDP-glucuronosyltransferase) refers to a family of enzymes that perform glucuronidation—a process that helps make various compounds more water-soluble so your body can eliminate them more efficiently. UGT activity supports the clearance of normal waste products (like bilirubin from red blood cell breakdown), certain hormones, environmental chemicals (including BPA-related compounds), and many medications. UGT function is also connected to antioxidant defense because these pathways interact with glutathione-related protection against oxidative stress.
: UGT (Detox) genes are important because genetic variants can change how efficiently UGT enzymes work. Lower-activity variants—especially in UGT1A1 (such as UGT1A1*28, and other reduced-function alleles reported in research)—may reduce detox capacity and contribute to higher bilirubin levels or increased sensitivity to certain drugs and chemicals. Other UGT variants can influence oxidative stress balance (through glutathione-related mechanisms) and may affect how you respond to specific exposures, including medications. Knowing your variants helps you understand your personal detox “speed,” potential sensitivities, and where supportive strategies may be most beneficial.
: Based on your UGT (Detox) results, you’ll receive 5 personalized recommendations that translate your genetics into practical next steps. These include dietary recommendations (foods and patterns that support detox and antioxidant defenses), lifestyle recommendations (ways to reduce avoidable chemical load and support healthy clearance), and supplement recommendations (when appropriate, targeted options aligned with your genotype). The goal is to help you make informed, actionable choices that match your body’s detox capacity—especially around medication considerations, environmental exposures, and oxidative stress support.
: Yes. UGT1A1 plays a central role in processing bilirubin, a normal waste product created when red blood cells are broken down. Research shows that certain UGT1A1 variants are associated with reduced enzyme activity, which can slow bilirubin clearance and contribute to higher bilirubin levels in some people. These same reduced-function variants may also indicate slower glucuronidation for other compounds, which can influence overall detox efficiency and sensitivity to specific drugs or environmental chemicals. A DNA-based UGT report helps identify whether you carry variants linked to lower activity and provides personalized strategies to support healthy detox pathways.
: A UGT (Detox) genetic test can highlight variants that may change how quickly you glucuronidate (process) certain medications and chemicals. Because UGT enzymes are involved in metabolizing a meaningful portion of drugs and in clearing compounds like BPA-related chemicals and steroid hormones, variants in genes such as UGT1A1, UGT1A6, and UGT2B7 can help explain why some people experience stronger effects, side effects, or reduced effectiveness with certain substances. This report analyzes 11 SNPs and converts your results into 5 personalized dietary, lifestyle, and supplement recommendations—so you can make more informed choices and have better-context conversations with your healthcare provider, especially when medications are involved.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.77 out of 5 based on 13 customer ratings

4.8 (14 reviews)

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Crystal A.

Rated 5 out of 5
I’m a 52 year old with a family history of “sluggish liver” labs, and this UGT (Detox) report helped me connect dots without panic. The recommendations were clear and doable. I cut grapefruit juice completely, swapped a few pantry staples to reduce glyphosate exposure, and used activated charcoal only on occasional heavy meals, exactly as the report cautioned. I also tried TUDCA and milk thistle for a month, and my post dinner heaviness improved noticeably. What I liked most was the explanation of why UGT pathways matter, it made the changes feel purposeful.
Nadia F.

Rated 5 out of 5
El informe me sorprendió con recomendaciones claras y fáciles de seguir. Comencé a evitar el jugo de toronja y a usar cardo mariano y ya noto cambios en mi energía.
Amara G.

Rated 5 out of 5
I took my ugt detox results to my nutritionist, and she was actually impressed by how much actionable info it gave. The supplement suggestions were specific and she said avoiding grapefruit juice was perfect for my genetics. She even said she’d recommend some of these tips to other patients!
Amara V.

Rated 5 out of 5
I picked up the UGT (Detox) report after years of feeling wiped out after certain foods and supplements, and it finally gave me a structured plan. The note about avoiding grapefruit juice was huge, I had no idea it could interfere with detox enzymes I already struggle with. I also appreciated the practical list for reducing glyphosate exposure, like which items to prioritize organic. I started a short course of TUDCA and added milk thistle with tree turmeric, and within two weeks my morning grogginess eased and my skin looked less dull. It felt personalized, not generic.
Melissa F.

Rated 3 out of 5
Honestly, I doubted DNA stuff would be useful for me. But the way it connected specific supplements and foods to my actual genes made me rethink a lot. Still think some stuff was obvious but the details about avoiding glyphosate actually helped.

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UGT (Detox)

Product features

Understanding Your UGT (Detox) Variants: A DNA Gene Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

What does the UGT (Detox) gene do?

Why is the UGT (Detox) gene important?

What can I do based on my UGT (Detox) results?

Can UGT1A1 variants affect bilirubin levels and detoxification?

What can a UGT (Detox) genetic test tell me about medication and chemical sensitivity?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers